Faculty
Roberta McKean-Cowdin
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Uncorrected Refractive Error in the African American Eye Disease Study JAMA Ophthalmol. 2024 Apr 01; 142(4):292-298. . View in PubMed
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology Nature. 2024 Mar; 627(8003):347-357. . View in PubMed
Excess pancreatic cancer risk due to smoking and modifying effect of quitting smoking: The Multiethnic Cohort Study Cancer Causes Control. 2024 Mar; 35(3):541-548. . View in PubMed
Impact of environment on pediatric and adult brain tumors: The 2023 Brain Tumor Epidemiology Consortium meeting report Clin Neuropathol. 2024 Jan-Feb; 43(1):29-35. . View in PubMed
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants Nat Genet. 2023 Dec; 55(12):2065-2074. . View in PubMed
Breastfeeding and risk of childhood brain tumors: a report from the Childhood Cancer and Leukemia International Consortium Cancer Causes Control. 2023 Nov; 34(11):1005-1015. . View in PubMed
Multi-ancestry genome-wide study in >25 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications. medRxiv. 2023 Mar 31. . View in PubMed
Erratum: Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium HGG Adv. 2023 Jan 12; 4(1):100149. . View in PubMed
Optimal number and orientation of anterior segment OCT images to measure ocular biometric parameters in angle closure eyes: the Chinese American Eye Study Br J Ophthalmol. 2023 06; 107(6):795-801. . View in PubMed
Anterior segment biometric measurements explain misclassifications by a deep learning classifier for detecting gonioscopic angle closure Br J Ophthalmol. 2023 03; 107(3):349-354. . View in PubMed
Classification of Angle Closure Severity by Hierarchical Cluster Analysis of Ocular Biometrics in the Dark and Light Transl Vis Sci Technol. 2023 09 01; 12(9):4. . View in PubMed
Refractive Error and Anterior Chamber Depth as Risk Factors in Primary Angle Closure Disease: The Chinese American Eye Study J Glaucoma. 2023 04 01; 32(4):257-264. . View in PubMed
Racial and Ethnic Differences in the Roles of Myopia and Ocular Biometrics as Risk Factors for Primary Open-Angle Glaucoma Invest Ophthalmol Vis Sci. 2023 06 01; 64(7):4. . View in PubMed
Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium HGG Adv. 2022 Apr 14; 3(2):100099. . View in PubMed
The International Family Study of Nonsyndromic Orofacial Clefts: Design and Methods Cleft Palate Craniofac J. 2022 Apr; 59(4_suppl2):S37-S47. . View in PubMed
Visual Field Loss Impacts Vision-Specific Quality of Life by Race and Ethnicity: The Multiethnic Ophthalmology Cohorts of California Study Ophthalmology. 2022 06; 129(6):668-678. . View in PubMed
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation Nat Genet. 2022 05; 54(5):560-572. . View in PubMed
Ocular Biometric Determinants of Dark-to-Light Change in Angle Width: The Chinese American Eye Study Am J Ophthalmol. 2022 05; 237:183-192. . View in PubMed
A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry Eur Urol. 2022 05; 81(5):458-462. . View in PubMed
Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction Nat Genet. 2021 Mar; 53(3):413. . View in PubMed
Impact of Visual Field Loss on Vision-Specific Quality of Life in African Americans: The African American Eye Disease Study Am J Ophthalmol. 2021 09; 229:52-62. . View in PubMed
Retinal Nerve Fiber Layer Thickness in Healthy Eyes of Black, Chinese, and Latino Americans: A Population-Based Multiethnic Study Ophthalmology. 2021 07; 128(7):1005-1015. . View in PubMed
FACTORS ASSOCIATED WITH PREVALENT LENS OPACITIES IN CHINESE AMERICAN ADULTS: THE CHINESE AMERICAN EYE STUDY Ophthalmic Epidemiol. 2021 02; 28(1):48-62. . View in PubMed
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction Nat Genet. 2021 01; 53(1):65-75. . View in PubMed
Parental Occupation and Risk of Childhood Retinoblastoma in Denmark J Occup Environ Med. 2021 03 01; 63(3):256-261. . View in PubMed
Trends in Acute Lymphoblastic Leukemia Incidence in the United States by Race/Ethnicity From 2000 to 2016 Am J Epidemiol. 2021 04 06; 190(4):519-527. . View in PubMed
The role of smoke from cooking indoors over an open flame and parental smoking on the risk of cleft lip and palate: A case- control study in 7 low-resource countries J Glob Health. 2020 Dec; 10(2):020410. . View in PubMed
ErratumMultiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Diabetes 2019;68:441-456. Diabetes. 2020 Jun; 69(6):1306. . View in PubMed
A genome-wide association study on medulloblastoma J Neurooncol. 2020 Apr; 147(2):309-315. . View in PubMed
Effect of Angle Narrowing on Sectoral Variation of Anterior Chamber Angle Width: The Chinese American Eye Study Ophthalmol Glaucoma. 2020 Mar-Apr; 3(2):130-138. . View in PubMed
Ocular Biometric Determinants of Anterior Chamber Angle Width in Chinese Americans: The Chinese American Eye Study Am J Ophthalmol. 2020 12; 220:19-26. . View in PubMed
Outdoor artificial light at night and risk of non-Hodgkin lymphoma among women in the California Teachers Study cohort Cancer Epidemiol. 2020 12; 69:101811. . View in PubMed
A Mitochondrial Genome-Wide Association Study of Cataract in a Latino Population Transl Vis Sci Technol. 2020 05; 9(6):25. . View in PubMed
Pediatric glioma and medulloblastoma risk and population demographics: a Poisson regression analysis Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa089. . View in PubMed
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity Nat Genet. 2019 Jul; 51(7):1191-1192. . View in PubMed
Differences in Anterior Chamber Angle Assessments Between Gonioscopy, EyeCam, and Anterior Segment OCT: The Chinese American Eye Study Transl Vis Sci Technol. 2019 Mar; 8(2):5. . View in PubMed
Factors Associated with Visual Impairment in Chinese American Adults: The Chinese American Eye Study Ophthalmic Epidemiol. 2019 10; 26(5):329-335. . View in PubMed
Predisposing germline mutations in high hyperdiploid acute lymphoblastic leukemia in children Genes Chromosomes Cancer. 2019 10; 58(10):723-730. . View in PubMed
Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control Diabetes. 2019 02; 68(2):441-456. . View in PubMed
Correlation between Intraocular Pressure and Angle Configuration Measured by OCT: The Chinese American Eye Study Ophthalmol Glaucoma. 2018 Nov-Dec; 1(3):158-166. . View in PubMed
Quantitative Evaluation of Gonioscopic and EyeCam Assessments of Angle Dimensions Using Anterior Segment Optical Coherence Tomography Transl Vis Sci Technol. 2018 Nov; 7(6):33. . View in PubMed
Factors Associated with Prevalent Diabetic Retinopathy in Chinese Americans: The Chinese American Eye Study Ophthalmol Retina. 2018 Feb; 2(2):96-105. . View in PubMed
Allergies and Childhood Acute Lymphoblastic Leukemia: A Case-Control Study and Meta-analysis Cancer Epidemiol Biomarkers Prev. 2018 10; 27(10):1142-1150. . View in PubMed
The African American Eye Disease Study: Design and Methods Ophthalmic Epidemiol. 2018 08; 25(4):306-314. . View in PubMed
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity Nat Genet. 2018 05; 50(5):766-767. . View in PubMed
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity Nat Genet. 2018 05; 50(5):765-766. . View in PubMed
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes Nat Genet. 2018 04; 50(4):559-571. . View in PubMed
Factors Associated with Age-Related Macular Degeneration in Chinese American Adults: The Chinese American Eye Study (CHES) Ophthalmol Retina. 2018 03; 2(3):209-216. . View in PubMed
Prevalence and Characteristics of Myopic Degeneration in an Adult Chinese American Population: The Chinese American Eye Study Am J Ophthalmol. 2018 03; 187:34-42. . View in PubMed
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity Nat Genet. 2018 01; 50(1):26-41. . View in PubMed
A germ-line deletion of APOBEC3B does not contribute to subtype-specific childhood acute lymphoblastic leukemia etiology Haematologica. 2018 01; 103(1):e29-e31. . View in PubMed
BMI1 enhancer polymorphism underlies chromosome 10p1231 association with childhood acute lymphoblastic leukemia. Int J Cancer. 2018 12 01; 143(11):2647-2658. . View in PubMed
GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q2421. Nat Commun. 2018 01 18; 9(1):286. . View in PubMed
Self-reported Use of Eye Care Among Adult Chinese Americans: The Chinese American Eye Study Am J Ophthalmol. 2017 Apr; 176:183-193. . View in PubMed
Trends in childhood leukemia incidence over two decades from 1992 to 2013 Int J Cancer. 2017 Mar 01; 140(5):1000-1008. . View in PubMed
Prevalence and Risk Factors for Refractive Error in Adult Chinese Americans: The Chinese American Eye Study Am J Ophthalmol. 2017 Mar; 175:201-212. . View in PubMed
Intrauterine Device Use and Cervical Cancer Risk: A Systematic Review and Meta-analysis Obstet Gynecol. 2017 12; 130(6):1226-1236. . View in PubMed
Correlates of Prenatal and Early-Life Tobacco Smoke Exposure and Frequency of Common Gene Deletions in Childhood Acute Lymphoblastic Leukemia Cancer Res. 2017 04 01; 77(7):1674-1683. . View in PubMed
Prevalence of Diabetic Retinopathy in Adult Chinese American Individuals: The Chinese American Eye Study JAMA Ophthalmol. 2016 May 01; 134(5):563-569. . View in PubMed
Prevalence of Age-Related Macular Degeneration in Chinese American Adults: The Chinese American Eye Study JAMA Ophthalmol. 2016 May 01; 134(5):571-577. . View in PubMed
Tobacco Smoke and Ras Mutations Among Latino and Non-Latino Children with Acute Lymphoblastic Leukemia Arch Med Res. 2016 11; 47(8):677-683. . View in PubMed
Prevalence of Lens Opacities in Adult Chinese Americans: The Chinese American Eye Study (CHES) Invest Ophthalmol Vis Sci. 2016 12 01; 57(15):6692-6699. . View in PubMed
Age-Related Macular Degeneration and Quality of Life in Latinos: The Los Angeles Latino Eye Study JAMA Ophthalmol. 2016 06 01; 134(6):683-90. . View in PubMed
American Brain Tumor Association Adolescent and Young Adult Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012 Neuro Oncol. 2016 Jan; 18 Suppl 1:i1-i50. . View in PubMed
Visual Impairment and Blindness in Adults in the United States: Demographic and Geographic Variations From 2015 to 2050 JAMA Ophthalmol. 2016 07 01; 134(7):802-9. . View in PubMed
Prevalence and Causes of Visual Impairment and Blindness in Chinese American Adults: The Chinese American Eye Study JAMA Ophthalmol. 2016 07 01; 134(7):785-93. . View in PubMed
Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types J Natl Cancer Inst. 2015 Dec; 107(12):djv279. . View in PubMed
Response to "importance of C-3 epimer of 25-hydroxyvitamin D in dried blood spots of neonatal population" Int J Cancer. 2015 Aug 01; 137(3):751. . View in PubMed
Further Confirmation of Germline Glioma Risk Variant rs78378222 in TP53 and Its Implication in Tumor Tissues via Integrative Analysis of TCGA Data Hum Mutat. 2015 Jul; 36(7):684-8. . View in PubMed
Neonatal vitamin D and childhood brain tumor risk Int J Cancer. 2015 May 15; 136(10):2481-5. . View in PubMed
Rising rates of acute lymphoblastic leukemia in Hispanic children: trends in incidence from 1992 to 2011 Blood. 2015 May 07; 125(19):3033-4. . View in PubMed
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility Nat Commun. 2015 Jan 29; 6:5897. . View in PubMed
Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p1533. Hum Mol Genet. 2014 Dec 15; 23(24):6616-33. . View in PubMed
Childhood brain tumor epidemiology: a brain tumor epidemiology consortium review Cancer Epidemiol Biomarkers Prev. 2014 Dec; 23(12):2716-36. . View in PubMed
Lipids, lipid genes, and incident age-related macular degeneration: the three continent age-related macular degeneration consortiumAm J Ophthalmol. 2014 Sep; 158(3):513-24. e3. . View in PubMed
Harmonizing the classification of age-related macular degeneration in the three-continent AMD consortium Ophthalmic Epidemiol. 2014 Feb; 21(1):14-23. . View in PubMed
Estimating risks for variants of unknown significance according to their predicted pathogenicity classes with application to BRCA1 Breast Cancer Res Treat. 2014 Feb; 144(1):171-7. . View in PubMed
Trends in childhood brain tumor incidence, 1973-2009 J Neurooncol. 2013 Nov; 115(2):153-60. . View in PubMed
Development of a vision-targeted health-related quality of life item measure Qual Life Res. 2013 Nov; 22(9):2477-87. . View in PubMed
Prevalence of amblyopia or strabismus in asian and non-Hispanic white preschool children: multi-ethnic pediatric eye disease study Ophthalmology. 2013 Oct; 120(10):2117-24. . View in PubMed
Prevalence of myopia, hyperopia, and astigmatism in non-Hispanic white and Asian children: multi-ethnic pediatric eye disease study Ophthalmology. 2013 Oct; 120(10):2109-16. . View in PubMed
Prevalence and causes of visual impairment in Asian and non-Hispanic white preschool children: Multi-ethnic Pediatric Eye Disease Study Ophthalmology. 2013 Jun; 120(6):1220-6. . View in PubMed
Can mycobacterial katG genetic changes in isoniazid-resistant tuberculosis influence human disease features? Int J Tuberc Lung Dis. 2013 May; 17(5):644-51.. View in PubMed
Vision assessment using the NIH Toolbox Neurology. 2013 Mar 12; 80(11 Suppl 3):S37-40. . View in PubMed
Parental smoking and risk of childhood brain tumors by functional polymorphisms in polycyclic aromatic hydrocarbon metabolism genes PLoS One. 2013; 8(11):e79110. . View in PubMed
Variation in inflammatory cytokine/growth-factor genes and mammographic density in premenopausal women aged 50-55 PLoS One. 2013; 8(6):e65313. . View in PubMed
Genome-wide association study of glioma and meta-analysis Hum Genet. 2012 Dec; 131(12):1877-88. . View in PubMed
DEXA measures of body fat percentage and acute phase proteins among breast cancer survivors: a cross-sectional analysis BMC Cancer. 2012 Aug 08; 12:343. . View in PubMed
Association between adult height, genetic susceptibility and risk of glioma Int J Epidemiol. 2012 Aug; 41(4):1075-85. . View in PubMed
Detectable clonal mosaicism and its relationship to aging and cancer Nat Genet. 2012 May 06; 44(6):651-8. . View in PubMed
New portable tool to screen vestibular and visual function--National Institutes of Health Toolbox initiative J Rehabil Res Dev. 2012; 49(2):209-20. . View in PubMed
Genotype Imputation for Latinos Using the HapMap and 1000 Genomes Project Reference Panels Front Genet. 2012; 3:117. . View in PubMed
Birth weight and other prenatal factors and risk of breast cancer in Asian-Americans Breast Cancer Res Treat. 2011 Dec; 130(3):917-25. . View in PubMed
Characteristics of triple-negative breast cancer in patients with a BRCA1 mutation: results from a population-based study of young women J Clin Oncol. 2011 Nov 20; 29(33):4373-80. . View in PubMed
Estrogenic botanical supplements, health-related quality of life, fatigue, and hormone-related symptoms in breast cancer survivors: a HEAL study report BMC Complement Altern Med. 2011 Nov 08; 11:109. . View in PubMed
Childhood brain tumors and maternal cured meat consumption in pregnancy: differential effect by glutathione S-transferases Cancer Epidemiol Biomarkers Prev. 2011 Nov; 20(11):2413-9. . View in PubMed
Risk factors associated with childhood strabismus: the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies Ophthalmology. 2011 Nov; 118(11):2251-61. . View in PubMed
Risk factors for decreased visual acuity in preschool children: the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies Ophthalmology. 2011 Nov; 118(11):2262-73. . View in PubMed
Risk factors for hyperopia and myopia in preschool children the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies Ophthalmology. 2011 Oct; 118(10):1966-73. . View in PubMed
Risk factors for astigmatism in preschool children: the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies Ophthalmology. 2011 Oct; 118(10):1974-81. . View in PubMed
Risk factors for four-year incidence and progression of age-related macular degeneration: the los angeles latino eye study Am J Ophthalmol. 2011 Sep; 152(3):385-395. . View in PubMed
The impact of change in visual field on health-related quality of life the los angeles latino eye study Ophthalmology. 2011 Jul; 118(7):1310-7. . View in PubMed
Severity of diabetic retinopathy and health-related quality of life: the Los Angeles Latino Eye Study Ophthalmology. 2011 Apr; 118(4):649-55. . View in PubMed
General health-related quality of life in preschool children with strabismus or amblyopia Ophthalmology. 2011 Mar; 118(3):574-80. . View in PubMed
Longitudinal changes in visual acuity and health-related quality of life: the Los Angeles Latino Eye studyOphthalmology. 2010 Oct; 117(10):1900-71907. e1. . View in PubMed
Patterns of regular use of mammography--body weight and ethnicity: the Multiethnic Cohort J Am Acad Nurse Pract. 2010 Mar; 22(3):162-9. . View in PubMed
Central and peripheral visual impairment and the risk of falls and falls with injuryOphthalmology. 2010 Feb; 117(2):199-206. e1. . View in PubMed
Childhood brain tumors, residential insecticide exposure, and pesticide metabolism genes Environ Health Perspect. 2010 Jan; 118(1):144-9. . View in PubMed
Ambient air pollution and brain cancer mortality Cancer Causes Control. 2009 Nov; 20(9):1645-51. . View in PubMed
Ethnic differences in the use of regular mammography: the multiethnic cohort Breast Cancer Res Treat. 2009 May; 115(1):163-70. . View in PubMed
Associations between polymorphisms in DNA repair genes and glioblastoma Cancer Epidemiol Biomarkers Prev. 2009 Apr; 18(4):1118-26. . View in PubMed
Genetic variants in association studies--review of strengths and weaknesses in study design and current knowledge of impact on cancer risk Acta Oncol. 2009; 48(7):948-54. . View in PubMed
Effect of reproductive factors and oral contraceptives on breast cancer risk in BRCA1/2 mutation carriers and noncarriers: results from a population-based study Cancer Epidemiol Biomarkers Prev. 2008 Nov; 17(11):3170-8. . View in PubMed
Impact of visual field loss on health-related quality of life in glaucoma: the Los Angeles Latino Eye StudyOphthalmology. 2008 Jun; 115(6):941-948. e1. . View in PubMed
Evaluation of unclassified variants in the breast cancer susceptibility genes BRCA1 and BRCA2 using five methods: results from a population-based study of young breast cancer patients Breast Cancer Res. 2008; 10(1):R19. . View in PubMed
The ADRB3 Trp64Arg variant and obesity in African-American breast cancer cases Int J Obes (Lond). 2007 Jul; 31(7):1110-8. . View in PubMed
Severity of visual field loss and health-related quality of life Am J Ophthalmol. 2007 Jun; 143(6):1013-23. . View in PubMed
Serum organochlorines and breast cancer: a case-control study among African-American women Cancer Causes Control. 2007 Feb; 18(1):29-39. . View in PubMed
An association between a common variant (G972R) in the IRS-1 gene and sex hormone levels in post-menopausal breast cancer survivors Breast Cancer Res Treat. 2006 Oct; 99(3):323-31. . View in PubMed
Maternal medication use and the risk of brain tumors in the offspring: the SEARCH international case-control study Int J Cancer. 2006 Mar 01; 118(5):1302-8. . View in PubMed
Head circumference at birth linked to cancer in childhood Lancet Oncol. 2006 Jan; 7(1):4-5. . View in PubMed
A haplotype-based case-control study of BRCA1 and sporadic breast cancer risk Cancer Res. 2005 Aug 15; 65(16):7516-22. . View in PubMed
BRCA1 variants in a family study of African-American and Latina women Hum Genet. 2005 May; 116(6):497-506. . View in PubMed
Prescription drug use and risk of acute myeloid leukemia by French-American-British subtype: results from a Los Angeles County case-control study Int J Cancer. 2005 Apr 20; 114(4):634-8. . View in PubMed
Maternal prenatal exposure to nitrosatable drugs and childhood brain tumours Int J Epidemiol. 2003 Apr; 32(2):211-7. . View in PubMed
IGF1 genotype, mean plasma level and breast cancer risk in the Hawaii/Los Angeles multiethnic cohort Br J Cancer. 2003 Jan 27; 88(2):277-82. . View in PubMed
Concerning the CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis Mutagenesis. 2002 Sep; 17(5):445-6; author reply 447-8. . View in PubMed
Germ-line HER-2 variant and breast cancer risk by stage of disease Cancer Res. 2001 Dec 01; 61(23):8393-4. . View in PubMed
Risk of endometrial cancer and estrogen replacement therapy history by CYP17 genotype Cancer Res. 2001 Feb 01; 61(3):848-9. . View in PubMed
Building a multigenic model of breast cancer susceptibility: CYP17 and HSD17B1 are two important candidates Cancer Res. 2001 Jan 15; 61(2):785-9. . View in PubMed
Reliability of demographic, smoking and occupational data provided by mothers vsfathers in a childhood cancer study. Paediatr Perinat Epidemiol. 2000 Jul; 14(3):257-62. . View in PubMed
Ethnic differences in post-menopausal plasma oestrogen levels: high oestrone levels in Japanese-American women despite low weight Br J Cancer. 2000 Jun; 82(11):1867-70. . View in PubMed
Declining cancer rates in the 1990s J Clin Oncol. 2000 Jun; 18(11):2258-68. . View in PubMed
Cytochrome P450c17alpha gene (CYP17) polymorphism predicts use of hormone replacement therapy Cancer Res. 1999 Aug 15; 59(16):3908-10. . View in PubMed
Parental occupation and childhood brain tumors: astroglial and primitive neuroectodermal tumors J Occup Environ Med. 1998 Apr; 40(4):332-40. . View in PubMed