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Jaana A Hartiala
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COVID-19 Is a Coronary Artery Disease Risk Equivalent and Exhibits a Genetic Interaction With ABO Blood Type Arterioscler Thromb Vasc Biol. 2024 Oct 09. . View in PubMed
Comprehensive Clinical and Genetic Analyses of Circulating Bile Acids and Their Associations With Diabetes and Its Indices Diabetes. 2024 Aug 01; 73(8):1215-1228. . View in PubMed
Publisher Correction: A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk Nat Med. 2024 Jun; 30(6):1791. . View in PubMed
Blocking CD226 regulates type 2 innate lymphoid cell effector function and alleviates airway hyperreactivityJ Allergy Clin Immunol. 2024 May; 153(5):1406-1422. e6. . View in PubMed
A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk Nat Med. 2024 Feb; 30(2):424-434. . View in PubMed
Relationships and Mendelian Randomization of Gut Microbe-Derived Metabolites with Metabolic Syndrome Traits in the METSIM Cohort Metabolites. 2024 03 20; 14(3). . View in PubMed
Effect of Genetic and Dietary Perturbation of Glycine Metabolism on Atherosclerosis in Humans and Mice medRxiv. 2023 Dec 11. . View in PubMed
Effect of menopausal hormone therapy on methylation levels in early and late postmenopausal women Clin Epigenetics. 2022 07 18; 14(1):90. . View in PubMed
Clinical Intervention to Reduce Dietary Sugar Does Not Affect Liver Fat in Latino Youth, Regardless of PNPLA3 Genotype: A Randomized Controlled Trial J Nutr. 2022 07 06; 152(7):1655-1665. . View in PubMed
Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis Front Physiol. 2022; 13:909870. . View in PubMed
Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality Eur Heart J. 2021 05 07; 42(18):1742-1756. . View in PubMed
Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection J Lipid Res. 2021; 62:100061. . View in PubMed
Gene-Environment Interactions for Cardiovascular Disease Curr Atheroscler Rep. 2021 10 14; 23(12):75. . View in PubMed
Genome-wide analysis identifies novel susceptibility loci for myocardial infarction Eur Heart J. 2021 03 01; 42(9):919-933. . View in PubMed
Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus Circ Genom Precis Med. 2020 12; 13(6):e002769. . View in PubMed
Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma Nat Commun. 2020 04 15; 11(1):1776. . View in PubMed
Association of Factor V Leiden With Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data Circulation. 2020 08 11; 142(6):546-555. . View in PubMed
A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity PLoS Genet. 2019 12; 15(12):e1008528. . View in PubMed
Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events Circ Genom Precis Med. 2019 04; 12(4):e002471. . View in PubMed
Subsequent Event Risk in Individuals With Established Coronary Heart Disease Circ Genom Precis Med. 2019 04; 12(4):e002470. . View in PubMed
Exposure to Nanoscale Particulate Matter from Gestation to Adulthood Impairs Metabolic Homeostasis in Mice Sci Rep. 2019 02 12; 9(1):1816. . View in PubMed
Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease J Am Heart Assoc. 2019 05 21; 8(10):e011922. . View in PubMed
Interethnic analyses of blood pressure loci in populations of East Asian and European descent Nat Commun. 2018 11 28; 9(1):5052. . View in PubMed
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk JCI Insight. 2018 03 22; 3(6). . View in PubMed
Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions Circulation. 2017 Jun 13; 135(24):2336-2353. . View in PubMed
The Genetic Architecture of Coronary Artery Disease: Current Knowledge and Future Opportunities Curr Atheroscler Rep. 2017 Feb; 19(2):6. . View in PubMed
Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study Lancet Diabetes Endocrinol. 2017 07; 5(7):534-543. . View in PubMed
Proceedings of the 11th Congress of the International Society of Nutrigenetics and Nutrigenomics (ISNN 2017) J Nutrigenet Nutrigenomics. 2017; 10(5-6):155-162. . View in PubMed
Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice J Assoc Res Otolaryngol. 2016 Oct; 17(5):417-31. . View in PubMed
Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease Nat Commun. 2016 Jan 29; 7:10558. . View in PubMed
Ambient Air Pollution Is Associated With the Severity of Coronary Atherosclerosis and Incident Myocardial Infarction in Patients Undergoing Elective Cardiac Evaluation J Am Heart Assoc. 2016 07 28; 5(8). . View in PubMed
The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency-Specific Genetic Determinants G3 (Bethesda). 2015 Sep 04; 5(11):2329-39. . View in PubMed
Selected vitamin D metabolic gene variants and risk for autism spectrum disorder in the CHARGE Study Early Hum Dev. 2015 Aug; 91(8):483-9. . View in PubMed
The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice Stem Cell Reports. 2015 Jul 14; 5(1):125-38. . View in PubMed
Identification of a Novel Mucin Gene HCG22 Associated With Steroid-Induced Ocular Hypertension Invest Ophthalmol Vis Sci. 2015 Apr; 56(4):2737-48. . View in PubMed
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction Nature. 2015 Feb 05; 518(7537):102-6. . View in PubMed
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation Nat Genet. 2015 11; 47(11):1282-1293. . View in PubMed
Genetic variation in MTNR1B is associated with gestational diabetes mellitus and contributes only to the absolute level of beta cell compensation in Mexican Americans Diabetologia. 2014 Jul; 57(7):1391-9. . View in PubMed
Comparative genome-wide association studies in mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and L-carnitine Arterioscler Thromb Vasc Biol. 2014 Jun; 34(6):1307-13. . View in PubMed
Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q231. Hum Mol Genet. 2014 Apr 15; 23(8):2198-209. . View in PubMed
Genetic and clinical markers of elevated liver fat content in overweight and obese Hispanic children Obesity (Silver Spring). 2013 Dec; 21(12):E790-7. . View in PubMed
Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia Hum Mol Genet. 2013 Aug 15; 22(16):3381-93. . View in PubMed
Aspirin hydrolysis in plasma is a variable function of butyrylcholinesterase and platelet-activating factor acetylhydrolase 1b2 (PAFAH1b2) J Biol Chem. 2013 Apr 26; 288(17):11940-8. . View in PubMed
Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis J Am Coll Cardiol. 2013 Mar 05; 61(9):957-70. . View in PubMed
Seventy-five genetic loci influencing the human red blood cell Nature. 2012 Dec 20; 492(7429):369-75. . View in PubMed
A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site Blood. 2012 Dec 06; 120(24):4859-68. . View in PubMed
Clinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2803-12. . View in PubMed
Arachidonate 5-lipoxygenase gene variants affect response to fish oil supplementation by healthy African Americans J Nutr. 2012 Aug; 142(8):1417-28. . View in PubMed
Association of a genetic risk score with prevalent and incident myocardial infarction in subjects undergoing coronary angiography Circ Cardiovasc Genet. 2012 Aug 01; 5(4):441-9. . View in PubMed
Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study Am J Clin Nutr. 2012 Jul; 96(1):80-9. . View in PubMed
Association of PLA2G4A with myocardial infarction is modulated by dietary PUFAs Am J Clin Nutr. 2012 Apr; 95(4):959-65. . View in PubMed
Clinical and genetic association of serum ceruloplasmin with cardiovascular risk Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2):516-22. . View in PubMed
New gene functions in megakaryopoiesis and platelet formation Nature. 2011 Nov 30; 480(7376):201-8. . View in PubMed
A novel g-1258G>A mutation in a conserved putative regulatory element of PAX9 is associated with autosomal dominant molar hypodontia. Clin Genet. 2011 Sep; 80(3):265-72. . View in PubMed
Prenatal vitamins, one-carbon metabolism gene variants, and risk for autism Epidemiology. 2011 Jul; 22(4):476-85. . View in PubMed
Genetic contribution of the leukotriene pathway to coronary artery disease Hum Genet. 2011 Jun; 129(6):617-27. . View in PubMed
ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation J Lipid Res. 2011 May; 52(5):991-1003. . View in PubMed
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project PLoS Genet. 2011 Feb 10; 7(2):e1001300. . View in PubMed
Genetic risk score and risk of myocardial infarction in Hispanics Circulation. 2011 Feb 01; 123(4):374-80. . View in PubMed
Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies Lancet. 2011 Jan 29; 377(9763):383-92. . View in PubMed
Lipoprotein(a) levels and long-term cardiovascular risk in the contemporary era of statin therapy J Lipid Res. 2010 Oct; 51(10):3055-61. . View in PubMed
Cardiac positron emission tomography/computed tomography imaging accurately detects anatomically and functionally significant coronary artery disease Circulation. 2010 Aug 10; 122(6):603-13. . View in PubMed
Additive effects of genetic variation in GCK and G6PC2 on insulin secretion and fasting glucose Diabetes. 2009 Dec; 58(12):2946-53. . View in PubMed
Functional analysis of 5-lipoxygenase promoter repeat variants Hum Mol Genet. 2009 Dec 01; 18(23):4521-9. . View in PubMed
Evidence for sex-specific associations between variation in acid phosphatase locus 1 (ACP1) and insulin sensitivity in Mexican-Americans J Clin Endocrinol Metab. 2009 Oct; 94(10):4094-102. . View in PubMed
Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans Obesity (Silver Spring). 2009 Apr; 17(4):729-36. . View in PubMed
A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus Hum Mol Genet. 2009 Feb 01; 18(3):569-79. . View in PubMed
Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction Am J Clin Nutr. 2008 Oct; 88(4):934-40. . View in PubMed
Identification of ALOX5 as a gene regulating adiposity and pancreatic function Diabetologia. 2008 Jun; 51(6):978-88. . View in PubMed
Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease Hum Genet. 2008 May; 123(4):399-408. . View in PubMed
Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans Diabetes. 2008 Apr; 57(4):1048-56. . View in PubMed
Allgrove syndrome in a Mexican American family is caused by an ancestral mutation derived from North Africa Clin Genet. 2008 Apr; 73(4):385-7. . View in PubMed
The effect of montelukast and low-dose theophylline on cardiovascular disease risk factors in asthmatics Chest. 2007 Sep; 132(3):868-74. . View in PubMed
Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican Americans Diabetes. 2007 May; 56(5):1481-5. . View in PubMed
A new locus for autosomal dominant amelogenesis imperfecta on chromosome 8q243. Hum Genet. 2007 Jan; 120(5):653-62. . View in PubMed
Nonconventional genetic risk factors for cardiovascular disease Curr Atheroscler Rep. 2006 May; 8(3):184-92. . View in PubMed
Rett syndrome in a 47,XXX patient with a de novo MECP2 mutation Am J Med Genet A. 2003 Oct 15; 122A(3):223-6. . View in PubMed
Genetic demography of Antioquia (Colombia) and the Central Valley of Costa Rica Hum Genet. 2003 May; 112(5-6):534-41. . View in PubMed
Transoesophageal echocardiography in selecting patients for anticoagulation after ischaemic stroke or transient ischaemic attack J Neurol Neurosurg Psychiatry. 2002 Jul; 73(1):29-33. . View in PubMed
Effect of medroxyprogesterone on pulmonary arterial pressure, exhaled nitric oxide, ECG and arterial blood gases J Intern Med. 2002 May; 251(5):421-8. . View in PubMed
Population-based twin study of the effects of migration from Finland to Sweden on endothelial function and intima-media thickness Arterioscler Thromb Vasc Biol. 2002 May 01; 22(5):832-7. . View in PubMed
A susceptibility locus for migraine with aura, on chromosome 4q24 Am J Hum Genet. 2002 Mar; 70(3):652-62. . View in PubMed
Reduced myocardial flow reserve relates to increased carotid intima-media thickness in healthy young men Atherosclerosis. 2001 Jun; 156(2):469-75. . View in PubMed
Coronary flow reserve: measurement with transthoracic Doppler echocardiography is reproducible and comparable with positron emission tomography Clin Physiol. 2001 Jan; 21(1):114-22. . View in PubMed
Reduced myocardial flow reserve does not impair exercise capacity in asymptomatic men Am J Cardiol. 1999 Nov 15; 84(10):1253-5A8. . View in PubMed
Genomewide scan for familial combined hyperlipidemia genes in finnish families, suggesting multiple susceptibility loci influencing triglyceride, cholesterol, and apolipoprotein B levels Am J Hum Genet. 1999 May; 64(5):1453-63. . View in PubMed
Glucose uptake in the chronically dysfunctional but viable myocardium Circulation. 1996 May 01; 93(9):1658-66. . View in PubMed
Exercise echocardiography in the diagnosis of coronary artery disease Ann Med. 1996 Feb; 28(1):73-7. . View in PubMed
Enhancement of myocardial [fluorine-18]fluorodeoxyglucose uptake by a nicotinic acid derivative J Nucl Med. 1994 Jun; 35(6):989-98. . View in PubMed
Exercise thallium-201 scintigraphy in the localization of myocardial ischaemia Clin Physiol. 1989 Dec; 9(6):555-65. . View in PubMed
Cigarette smoke affects lipolytic activity in isolated rat lungs Lipids. 1980 Jul; 15(7):539-43. . View in PubMed