Faculty
Charleston Chiang
Contact
American Society of Human Genetics: ASHG Human Genetics and Genomics Advances Outstanding Early Career Publication Award, 2023
: ASHG Charles J. Epstein Trainee Award for Excellence in Human Genetics Research Semi-finalist, 2017
: National Institute of Health NRSA Postdoctoral Fellowship (F32), 2013-2015
: National Science Foundation Graduate Student Fellowship, 2007-2010
Folate metabolism and risk of childhood acute lymphoblastic leukemia: a genetic pathway analysis from the Childhood Cancer and Leukemia International Consortium Cancer Epidemiol Biomarkers Prev. 2024 Jun 21. . View in PubMed
A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children Cell Genom. 2024 Apr 10; 4(4):100526. . View in PubMed
Imputation accuracy across global human populations Am J Hum Genet. 2024 Apr 05. . View in PubMed
Genome-wide assessment of genetic risk loci for childhood acute lymphoblastic leukemia in Japanese patients Haematologica. 2024 Apr 01; 109(4):1247-1252. . View in PubMed
The Promise of Inferring the Past Using the Ancestral Recombination Graph Genome Biol Evol. 2024 Feb 01; 16(2). . View in PubMed
Recombination map tailored to Native Hawaiians may improve robustness of genomic scans for positive selection Hum Genet. 2024 Jan; 143(1):85-99. . View in PubMed
The accuracy of polygenic score models for anthropometric traits and Type II Diabetes in the Native Hawaiian Population medRxiv. 2023 Dec 28. . View in PubMed
Tree-based QTL mapping with expected local genetic relatedness matrices Am J Hum Genet. 2023 Dec 07; 110(12):2077-2091. . View in PubMed
Imputation Accuracy Across Global Human Populations bioRxiv. 2023 Oct 26. . View in PubMed
A likelihood-based framework for demographic inference from genealogical trees bioRxiv. 2023 Oct 13. . View in PubMed
Evaluating genomic polygenic risk scores for childhood acute lymphoblastic leukemia in Latinos HGG Adv. 2023 Oct 12; 4(4):100239. . View in PubMed
Recombination map tailored to Native Hawaiians improves robustness of genomic scans for positive selection bioRxiv. 2023 Sep 02. . View in PubMed
Evaluating Genomic Polygenic Risk Scores for Childhood Acute Lymphoblastic Leukemia in Latinos medRxiv. 2023 Jun 12. . View in PubMed
Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics bioRxiv. 2023 Apr 18. . View in PubMed
Tree-based QTL mapping with expected local genetic relatedness matrices bioRxiv. 2023 Apr 08. . View in PubMed
Erratum: Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium HGG Adv. 2023 Jan 12; 4(1):100149. . View in PubMed
Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics Am J Hum Genet. 2023 11 02; 110(11):1853-1862. . View in PubMed
Inverted genomic regions between reference genome builds in humans impact imputation accuracy and decrease the power of association testing HGG Adv. 2023 01 12; 4(1):100159. . View in PubMed
Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium HGG Adv. 2022 Apr 14; 3(2):100099. . View in PubMed
Variant to function mapping at single-cell resolution through network propagation bioRxiv. 2022 Jan 24. . View in PubMed
Variant to function mapping at single-cell resolution through network propagation Nat Biotechnol. 2022 11; 40(11):1644-1653. . View in PubMed
Localized variation in ancestral admixture identifies pilocytic astrocytoma risk loci among Latino children PLoS Genet. 2022 09; 18(9):e1010388. . View in PubMed
A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry Eur Urol. 2022 05; 81(5):458-462. . View in PubMed
Genome-wide trans-ethnic meta-analysis identifies novel susceptibility loci for childhood acute lymphoblastic leukemia Leukemia. 2022 03; 36(3):865-868. . View in PubMed
A genealogical estimate of genetic relationships Am J Hum Genet. 2022 05 05; 109(5):812-824. . View in PubMed
Allele frequency differentiation at height-associated SNPs among continental human populations Eur J Hum Genet. 2021 10; 29(10):1542-1548. . View in PubMed
The impact of global and local Polynesian genetic ancestry on complex traits in Native Hawaiians PLoS Genet. 2021 02; 17(2):e1009273. . View in PubMed
Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry Am J Hum Genet. 2021 04 01; 108(4):564-582. . View in PubMed
Association of structural variation with cardiometabolic traits in Finns Am J Hum Genet. 2021 04 01; 108(4):583-596. . View in PubMed
Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences Hum Genomics. 2021 06 07; 15(1):34. . View in PubMed
The Opportunities and Challenges of Integrating Population Histories Into Genetic Studies for Diverse Populations: A Motivating Example From Native Hawaiians Front Genet. 2021; 12:643883. . View in PubMed
Genetic determinants of blood-cell traits influence susceptibility to childhood acute lymphoblastic leukemia Am J Hum Genet. 2021 10 07; 108(10):1823-1835. . View in PubMed
Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients Circ Genom Precis Med. 2020 10; 13(5):424-434. . View in PubMed
Genetic history from the Middle Neolithic to present on the Mediterranean island of Sardinia Nat Commun. 2020 02 24; 11(1):939. . View in PubMed
Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global PopulationsCell. 2020 09 03; 182(5):1198-1213. e14. . View in PubMed
Population-specific reference panels are crucial for genetic analyses: an example of the CREBRF locus in Native Hawaiians Hum Mol Genet. 2020 08 03; 29(13):2275-2284. . View in PubMed
Evidence of Polygenic Adaptation in Sardinia at Height-Associated Loci Ascertained from the Biobank Japan Am J Hum Genet. 2020 07 02; 107(1):60-71. . View in PubMed
Author Correction: Exome sequencing of Finnish isolates enhances rare-variant association power Nature. 2019 Nov; 575(7783):E4. . View in PubMed
Exome sequencing of Finnish isolates enhances rare-variant association power Nature. 2019 08; 572(7769):323-328. . View in PubMed
Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies Elife. 2019 03 21; 8. . View in PubMed
Genomic history of the Sardinian population Nat Genet. 2018 10; 50(10):1426-1434. . View in PubMed
A Comprehensive Map of Genetic Variation in the World's Largest Ethnic Group-Han Chinese Mol Biol Evol. 2018 11 01; 35(11):2736-2750. . View in PubMed
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study PLoS Genet. 2016 06; 12(6):e1006166. . View in PubMed
Population structure of Han Chinese in the modern Taiwanese population based on 10,000 participants in the Taiwan Biobank project Hum Mol Genet. 2016 12 15; 25(24):5321-5331. . View in PubMed
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape Nat Commun. 2016 11 23; 7:13357. . View in PubMed
Conflation of Short Identity-by-Descent Segments Bias Their Inferred Length Distribution G3 (Bethesda). 2016 05 03; 6(5):1287-96. . View in PubMed
Height-reducing variants and selection for short stature in Sardinia Nat Genet. 2015 Nov; 47(11):1352-1356. . View in PubMed
Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers Nat Genet. 2015 Nov; 47(11):1272-1281. . View in PubMed
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study PLoS Genet. 2015 Oct; 11(10):e1005378. . View in PubMed
Spatial localization of recent ancestors for admixed individuals G3 (Bethesda). 2014 Nov 03; 4(12):2505-18. . View in PubMed
Simulation of Finnish population history, guided by empirical genetic data, to assess power of rare-variant tests in Finland Am J Hum Genet. 2014 May 01; 94(5):710-20. . View in PubMed
Genomic analysis of the blood attributed to Louis XVI (1754-1793), king of France Sci Rep. 2014 Apr 24; 4:4666. . View in PubMed
Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European Nature. 2014 Mar 13; 507(7491):225-8. . View in PubMed
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry Nat Genet. 2013 Jun; 45(6):690-6. . View in PubMed
Evidence of widespread selection on standing variation in Europe at height-associated SNPs Nat Genet. 2012 Sep; 44(9):1015-9. . View in PubMed
Ultraconserved elements in the human genome: association and transmission analyses of highly constrained single-nucleotide polymorphisms Genetics. 2012 Sep; 192(1):253-66. . View in PubMed
Genome-wide association of copy-number variation reveals an association between short stature and the presence of low-frequency genomic deletions Am J Hum Genet. 2011 Dec 09; 89(6):751-9. . View in PubMed
The efficacy of detecting variants with small effects on the Affymetrix 60 platform using pooled DNA. Hum Genet. 2011 Nov; 130(5):607-21. . View in PubMed
Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: contributions from the CARe consortium Hum Mol Genet. 2011 Jun 01; 20(11):2285-95. . View in PubMed
Genome-wide association of anthropometric traits in African- and African-derived populations Hum Mol Genet. 2010 Jul 01; 19(13):2725-38. . View in PubMed
Rapid assessment of genetic ancestry in populations of unknown origin by genome-wide genotyping of pooled samples PLoS Genet. 2010 Mar 05; 6(3):e1000866. . View in PubMed
Ultraconserved elements: analyses of dosage sensitivity, motifs and boundaries Genetics. 2008 Dec; 180(4):2277-93. . View in PubMed
Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies PLoS One. 2008; 3(10):e3583. . View in PubMed
Direct regulation of adult brain function by the male-specific factor SRY Curr Biol. 2006 Feb 21; 16(4):415-20. . View in PubMed