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The Untapped Biomarker Potential of MicroRNAs for Health Risk-Benefit Analysis of Vaping vsSmoking. Cells. 2024 Aug 10; 13(16). . View in PubMed

Exploring the Utility of Long Non-Coding RNAs for Assessing the Health Consequences of Vaping Int J Mol Sci. 2024 Aug 05; 25(15). . View in PubMed

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The State of Research and Weight of Evidence on the Epigenetic Effects of Bisphenol A Int J Mol Sci. 2023 Apr 27; 24(9). . View in PubMed

Vaping Dose, Device Type, and E-Liquid Flavor are Determinants of DNA Damage in Electronic Cigarette Users Nicotine Tob Res. 2023 05 22; 25(6):1145-1154. . View in PubMed

DNA Hydroxymethylation in Smoking-Associated Cancers Int J Mol Sci. 2022 Feb 28; 23(5). . View in PubMed

Secondhand smoke affects reproductive functions by altering the mouse testis transcriptome, and leads to select intron retention in Pde1a Environ Int. 2022 03; 161:107086. . View in PubMed

The consequential impact of JUUL on youth vaping and the landscape of tobacco products: The state of play in the COVID-19 era Prev Med Rep. 2021 Jun; 22:101374. . View in PubMed

Hydroxychloroquine induces oxidative DNA damage and mutation in mammalian cells DNA Repair (Amst). 2021 10; 106:103180. . View in PubMed

Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer Mutat Res Rev Mutat Res. 2021 Jan-Jun; 787:108365. . View in PubMed

A novel role for vaping in mitochondrial gene dysregulation and inflammation fundamental to disease development Sci Rep. 2021 11 23; 11(1):22773. . View in PubMed

From Tobacco Cigarettes to Electronic Cigarettes: The Two Sides of a Nicotine Coin Front Oral Health. 2021; 2:790634. . View in PubMed

COVID-19: a pandemic converged with global tobacco epidemic and widespread vaping-state of the evidence Carcinogenesis. 2021 08 19; 42(8):1009-1022. . View in PubMed

Vaping epidemic: challenges and opportunities Cancer Causes Control. 2020 Jul; 31(7):663-667. . View in PubMed

Secondhand Smoke Induces Liver Steatosis through Deregulation of Genes Involved in Hepatic Lipid Metabolism Int J Mol Sci. 2020 Feb 14; 21(4). . View in PubMed

Hypomethylation of LINE-1 repeat elements and global loss of DNA hydroxymethylation in vapers and smokers Epigenetics. 2020 08; 15(8):816-829. . View in PubMed

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Vaping: A growing global health concern EClinicalMedicine. 2019 Dec; 17:100208. . View in PubMed

Deregulation of Biologically Significant Genes and Associated Molecular Pathways in the Oral Epithelium of Electronic Cigarette Users Int J Mol Sci. 2019 Feb 10; 20(3). . View in PubMed

DNA Hydroxymethylation at the Interface of the Environment and Nonalcoholic Fatty Liver Disease Int J Environ Res Public Health. 2019 08 05; 16(15). . View in PubMed

Mutation Analysis in Cultured Cells of Transgenic Rodents Int J Mol Sci. 2018 Jan 16; 19(1). . View in PubMed

A Versatile Assay for Detection of Aberrant DNA Methylation in Bladder Cancer Methods Mol Biol. 2018; 1655:29-41. . View in PubMed

The Lambda Select cII Mutation Detection System J Vis Exp. 2018 04 26; (134). . View in PubMed

An opportune and unique research to evaluate the public health impact of electronic cigarettes Cancer Causes Control. 2017 Oct; 28(10):1167-1171. . View in PubMed

Limited mutagenicity of electronic cigarettes in mouse or human cells in vitro Lung Cancer. 2017 10; 112:41-46. . View in PubMed

Expression of epigenetic modifiers is not significantly altered by exposure to secondhand smoke Lung Cancer. 2015 Dec; 90(3):598-603. . View in PubMed

Exposure of mice to secondhand smoke elicits both transient and long-lasting transcriptional changes in cancer-related functional networks Int J Cancer. 2015 May 15; 136(10):2253-63. . View in PubMed

The lingering question of menthol in cigarettes Cancer Causes Control. 2015 Feb; 26(2):165-169. . View in PubMed

Epigenetics of human melanoma: promises and challenges J Mol Cell Biol. 2014 Oct; 6(5):356-67. . View in PubMed

Electronic cigarettes: the road ahead Prev Med. 2014 Sep; 66:65-7. . View in PubMed

Epigenetic targeting of the Nanog pathway and signaling networks during chemical carcinogenesis Carcinogenesis. 2014 Aug; 35(8):1726-36. . View in PubMed

Alterations of DNA methylome in human bladder cancer Epigenetics. 2013 Oct; 8(10):1013-22. . View in PubMed

Genotoxicity of tobacco smoke-derived aromatic amines and bladder cancer: current state of knowledge and future research directions FASEB J. 2013 Jun; 27(6):2090-100. . View in PubMed

Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization Nucleic Acids Res. 2013 Jan 07; 41(1):182-95. . View in PubMed

Whole DNA methylome profiling in mice exposed to secondhand smoke Epigenetics. 2012 Nov; 7(11):1302-14. . View in PubMed

A high-throughput next-generation sequencing-based method for detecting the mutational fingerprint of carcinogens Nucleic Acids Res. 2012 Aug; 40(15):e116. . View in PubMed

New experimental data linking secondhand smoke exposure to lung cancer in nonsmokers FASEB J. 2012 May; 26(5):1845-54. . View in PubMed

Interactions between hepatitis B virus and aflatoxin B(1): effects on p53 induction in HepaRG cells J Gen Virol. 2012 Mar; 93(Pt 3):640-650. . View in PubMed

Organ specificity of the bladder carcinogen 4-aminobiphenyl in inducing DNA damage and mutation in mice Cancer Prev Res (Phila). 2012 Feb; 5(2):299-308. . View in PubMed

Measuring the formation and repair of UV damage at the DNA sequence level by ligation-mediated PCR Methods Mol Biol. 2012; 920:189-202. . View in PubMed

UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer Photochem Photobiol Sci. 2012 Jan; 11(1):90-7. . View in PubMed

Whole body exposure of mice to secondhand smoke induces dose-dependent and persistent promutagenic DNA adducts in the lung Mutat Res. 2011 Nov 01; 716(1-2):92-8. . View in PubMed

Wavelength dependence of ultraviolet radiation-induced DNA damage as determined by laser irradiation suggests that cyclobutane pyrimidine dimers are the principal DNA lesions produced by terrestrial sunlight FASEB J. 2011 Sep; 25(9):3079-91. . View in PubMed

Loss of Rassf1a enhances p53-mediated tumor predisposition and accelerates progression to aneuploidy Oncogene. 2011 Feb 10; 30(6):690-700. . View in PubMed

Uveal melanoma and GNA11 mutations: a new piece added to the puzzle Pigment Cell Melanoma Res. 2011 Feb; 24(1):18-20. . View in PubMed

Unveiling the methylation status of CpG dinucleotides in the substituted segment of the human p53 knock-in (Hupki) mouse genome Mol Carcinog. 2010 Dec; 49(12):999-1006. . View in PubMed

Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing FASEB J. 2010 Aug; 24(8):2612-9. . View in PubMed

Investigating the epigenetic effects of a prototype smoke-derived carcinogen in human cells PLoS One. 2010 May 12; 5(5):e10594. . View in PubMed

Transcription-dependent cytosine deamination is a novel mechanism in ultraviolet light-induced mutagenesis Curr Biol. 2010 Jan 26; 20(2):170-5. . View in PubMed

In vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposureGastroenterology. 2009 Sep; 137(3):1127-371137. e1-5. . View in PubMed

Mutational spectra of human cancer Hum Genet. 2009 Jun; 125(5-6):493-506. . View in PubMed

Acrolein: excessive cytotoxicity or potent mutagenicity? Chem Res Toxicol. 2009 May; 22(5):751-3; author reply 753-4.. View in PubMed

DNA-lesion mapping in mammalian cells Methods. 2009 May; 48(1):35-9. . View in PubMed

Sunlight ultraviolet irradiation and BRAF V600 mutagenesis in human melanoma Hum Mutat. 2008 Aug; 29(8):983-91. . View in PubMed

Second-hand smoke and human lung cancer Lancet Oncol. 2008 Jul; 9(7):657-66. . View in PubMed

Rapid repair of UVA-induced oxidized purines and persistence of UVB-induced dipyrimidine lesions determine the mutagenicity of sunlight in mouse cells FASEB J. 2008 Jul; 22(7):2379-92. . View in PubMed

Lack of mutagenicity of acrolein-induced DNA adducts in mouse and human cells Cancer Res. 2007 Dec 15; 67(24):11640-7. . View in PubMed

Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C Proc Natl Acad Sci U S A. 2007 Apr 03; 104(14):5953-8. . View in PubMed

Mutagenicity of ultraviolet A radiation in the lacI transgene in Big Blue mouse embryonic fibroblasts Mutat Res. 2007 Apr 01; 617(1-2):71-8. . View in PubMed

A review of mechanisms of acrylamide carcinogenicity Carcinogenesis. 2007 Mar; 28(3):519-28. . View in PubMed

Investigating human cancer etiology by DNA lesion footprinting and mutagenicity analysis Carcinogenesis. 2006 Aug; 27(8):1526-37. . View in PubMed

The role of DNA polymerase iota in UV mutational spectra Mutat Res. 2006 Jul 25; 599(1-2):58-65. . View in PubMed

DNA lesions induced by UV A1 and B radiation in human cells: comparative analyses in the overall genome and in the p53 tumor suppressor gene Proc Natl Acad Sci U S A. 2005 Jul 19; 102(29):10058-63. . View in PubMed

Investigating DNA adduct-targeted mutagenicity of tamoxifen: preferential formation of tamoxifen-DNA adducts in the human p53 gene in SV40 immortalized hepatocytes but not endometrial carcinoma cells Biochemistry. 2005 Jun 14; 44(23):8418-27. . View in PubMed

Mutations induced by ultraviolet light Mutat Res. 2005 Apr 01; 571(1-2):19-31. . View in PubMed

DNA adduction and mutagenic properties of acrylamide Mutat Res. 2005 Feb 07; 580(1-2):31-40. . View in PubMed

Similar mutagenicity of photoactivated porphyrins and ultraviolet A radiation in mouse embryonic fibroblasts: involvement of oxidative DNA lesions in mutagenesis Biochemistry. 2004 Dec 14; 43(49):15557-66. . View in PubMed

Biological consequences of 8-methoxypsoralen-photoinduced lesions: sequence-specificity of mutations and preponderance of T to C and T to a mutations J Invest Dermatol. 2004 Dec; 123(6):1140-6. . View in PubMed

DNA damage, repair, and mutation induction by (+)-Syn and (-)-anti-dibenzo[a,l]pyrene-11,12-diol-13,14-epoxides in mouse cells Cancer Res. 2004 Oct 15; 64(20):7321-8. . View in PubMed

Genotoxicity of acrylamide and glycidamide J Natl Cancer Inst. 2004 Jul 07; 96(13):1023-9. . View in PubMed

G-to-T transversions and small tandem base deletions are the hallmark of mutations induced by ultraviolet a radiation in mammalian cells Biochemistry. 2004 Jun 29; 43(25):8169-77. . View in PubMed

Enhancement of the mutagenicity of benzo(a)pyrene diol epoxide by a nonmutagenic dose of ultraviolet A radiation Cancer Res. 2003 Dec 15; 63(24):8708-16. . View in PubMed

Weak yet distinct mutagenicity of acrylamide in mammalian cells J Natl Cancer Inst. 2003 Jun 18; 95(12):889-96. . View in PubMed

Mutational signature of the proximate bladder carcinogen N-hydroxy-4-acetylaminobiphenyl: inconsistency with the p53 mutational spectrum in bladder cancer Cancer Res. 2002 Aug 01; 62(15):4331-8. . View in PubMed

A molecular dosimetry approach to assess human exposure to environmental tobacco smoke in pubs Carcinogenesis. 2002 Jul; 23(7):1171-6. . View in PubMed

Biomonitoring of tobacco smoke carcinogenicity by dosimetry of DNA adducts and genotyping and phenotyping of biotransformational enzymes: a review on polycyclic aromatic hydrocarbons Biomarkers. 2002 May-Jun; 7(3):209-29. . View in PubMed

Effects of oral administration of N-acetyl-L-cysteine: a multi-biomarker study in smokers Cancer Epidemiol Biomarkers Prev. 2002 Feb; 11(2):167-75. . View in PubMed

A multi-biomarker approach to study the effects of smoking on oxidative DNA damage and repair and antioxidative defense mechanisms Carcinogenesis. 2001 Mar; 22(3):395-401. . View in PubMed

Immunoperoxidase detection of 4-aminobiphenyl- and polycyclic aromatic hydrocarbons-DNA adducts in induced sputum of smokers and non-smokers Mutat Res. 2000 Jul 10; 468(2):125-35. . View in PubMed

Comparison between smoking-related DNA adduct analysis in induced sputum and peripheral blood lymphocytes Carcinogenesis. 2000 Jul; 21(7):1335-40. . View in PubMed

Applicability of induced sputum for molecular dosimetry of exposure to inhalatory carcinogens: 32P-postlabeling of lipophilic DNA adducts in smokers and nonsmokers Cancer Epidemiol Biomarkers Prev. 2000 Apr; 9(4):367-72. . View in PubMed

Immunoperoxidase detection of polycyclic aromatic hydrocarbon-DNA adducts in mouth floor and buccal mucosa cells of smokers and nonsmokers Environ Mol Mutagen. 2000; 36(2):127-33. . View in PubMed