Potassium-Alkali-Enriched Diet, Hypertension, and Proteinuria following Uninephrectomy J Am Soc Nephrol. 2024 Jun 24. . View in PubMed

Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and diseaseCell Stem Cell. 2024 Jun 06; 31(6):921-939. e17. . View in PubMed

Investigation of Basolateral Targeting Micelles for Drug Delivery Applications in Polycystic Kidney Disease Biomacromolecules. 2024 May 13; 25(5):2749-2761. . View in PubMed

The study of intercalated cells using ex vivo techniques: primary cell culture, cell lines, kidney slices, and organoids Am J Physiol Cell Physiol. 2024 01 01; 326(1):C229-C251. . View in PubMed

Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids bioRxiv. 2023 May 25. . View in PubMed

Metformin improves relevant disease parameters in an autosomal dominant polycystic kidney disease mouse model Am J Physiol Renal Physiol. 2022 01 01; 322(1):F27-F41. . View in PubMed

Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors Nat Commun. 2021 06 15; 12(1):3641. . View in PubMed

Activation of AMP-activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness FASEB J. 2020 05; 34(5):7036-7057. . View in PubMed

Ex vivo kidney slice preparations as a model system to study signaling cascades in kidney epithelial cells Methods Cell Biol. 2019; 153:185-203. . View in PubMed

Using Ex Vivo Kidney Slices to Study AMPK Effects on Kidney Proteins Methods Mol Biol. 2018; 1732:449-464. . View in PubMed

Sexual Dimorphic Pattern of Renal Transporters and Electrolyte Homeostasis J Am Soc Nephrol. 2017 Dec; 28(12):3504-3517. . View in PubMed

Insulin-like growth factor binding protein 7 and tissue inhibitor of metalloproteinases-2: differential expression and secretion in human kidney tubule cells Am J Physiol Renal Physiol. 2017 Feb 01; 312(2):F284-F296. . View in PubMed

Role of AMP-activated protein kinase in kidney tubular transport, metabolism, and disease Curr Opin Nephrol Hypertens. 2017 09; 26(5):375-383. . View in PubMed

Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats Front Physiol. 2017; 8:227. . View in PubMed

Muc1 enhances the ß-catenin protective pathway during ischemia-reperfusion injury Am J Physiol Renal Physiol. 2016 Mar 15; 310(6):F569-79. . View in PubMed

Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 &2 and AMP-activated Protein Kinase in the Kidney Sci Rep. 2016 10 26; 6:35952. . View in PubMed

Aurora kinase A activates the vacuolar H+-ATPase (V-ATPase) in kidney carcinoma cells Am J Physiol Renal Physiol. 2016 06 01; 310(11):F1216-28. . View in PubMed

Activation of the metabolic sensor AMP-activated protein kinase inhibits aquaporin-2 function in kidney principal cells Am J Physiol Renal Physiol. 2016 11 01; 311(5):F890-F900. . View in PubMed

Interactions between HIF-1a and AMPK in the regulation of cellular hypoxia adaptation in chronic kidney disease Am J Physiol Renal Physiol. 2015 Sep 01; 309(5):F414-28. . View in PubMed

Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action J Clin Invest. 2015 Sep; 125(9):3433-48. . View in PubMed

Muc1 is protective during kidney ischemia-reperfusion injury Am J Physiol Renal Physiol. 2015 Jun 15; 308(12):F1452-62. . View in PubMed

Collecting duct intercalated cell function and regulation Clin J Am Soc Nephrol. 2015 Feb 06; 10(2):305-24. . View in PubMed

Septic acute kidney injury: molecular mechanisms and the importance of stratification and targeting therapy Crit Care. 2014 Sep 02; 18(5):501. . View in PubMed

Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase Nat Chem Biol. 2014 Sep; 10(9):707-9. . View in PubMed

Epithelial transport during septic acute kidney injury Nephrol Dial Transplant. 2014 Jul; 29(7):1312-9. . View in PubMed

Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8506-11. . View in PubMed

Regulation of proximal tubule vacuolar H(+)-ATPase by PKA and AMP-activated protein kinase Am J Physiol Renal Physiol. 2014 May 01; 306(9):F981-95. . View in PubMed

Vasopressin induces apical expression of caveolin in rat kidney collecting duct principal cells Am J Physiol Renal Physiol. 2013 Dec 15; 305(12):F1783-95. . View in PubMed

Regulation of large-conductance Ca2+-activated K+ channels by WNK4 kinase Am J Physiol Cell Physiol. 2013 Oct 15; 305(8):C846-53. . View in PubMed

AMP-activated protein kinase regulates the vacuolar H+-ATPase via direct phosphorylation of the A subunit (ATP6V1A) in the kidney Am J Physiol Renal Physiol. 2013 Oct 01; 305(7):F943-56. . View in PubMed

Extracorporeal therapy for dabigatran removal in the treatment of acute bleeding: a single center experience Clin J Am Soc Nephrol. 2013 Sep; 8(9):1533-9. . View in PubMed

AMPK couples plasma renin to cellular metabolism by phosphorylation of ACC1 Am J Physiol Renal Physiol. 2013 Sep 01; 305(5):F679-90. . View in PubMed

PIP5KIß selectively modulates apical endocytosis in polarized renal epithelial cells PLoS One. 2013; 8(1):e53790. . View in PubMed

Sialylation of N-linked glycans mediates apical delivery of endolyn in MDCK cells via a galectin-9-dependent mechanism Mol Biol Cell. 2012 Sep; 23(18):3636-46. . View in PubMed

AMP-activated protein kinase regulation of kidney tubular transport Curr Opin Nephrol Hypertens. 2012 Sep; 21(5):523-33. . View in PubMed

Luminal flow modulates H+-ATPase activity in the cortical collecting duct (CCD) Am J Physiol Renal Physiol. 2012 Jan 01; 302(1):F205-15. . View in PubMed

Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells Am J Physiol Renal Physiol. 2011 Sep; 301(3):F622-33. . View in PubMed

AMP-activated protein kinase inhibits KCNQ1 channels through regulation of the ubiquitin ligase Nedd4-2 in renal epithelial cells Am J Physiol Renal Physiol. 2010 Dec; 299(6):F1308-19. . View in PubMed

SGLT1, a novel cardiac glucose transporter, mediates increased glucose uptake in PRKAG2 cardiomyopathy J Mol Cell Cardiol. 2010 Oct; 49(4):683-92. . View in PubMed

PKA regulates vacuolar H+-ATPase localization and activity via direct phosphorylation of the a subunit in kidney cells J Biol Chem. 2010 Aug 06; 285(32):24676-85. . View in PubMed

Regulation of the creatine transporter by AMP-activated protein kinase in kidney epithelial cells Am J Physiol Renal Physiol. 2010 Jul; 299(1):F167-77. . View in PubMed

Role of the energy sensor AMP-activated protein kinase in renal physiology and disease Am J Physiol Renal Physiol. 2010 May; 298(5):F1067-77. . View in PubMed

Vacuolar H+-ATPase apical accumulation in kidney intercalated cells is regulated by PKA and AMP-activated protein kinase Am J Physiol Renal Physiol. 2010 May; 298(5):F1162-9. . View in PubMed

Aquaporin 9 expression in the developing rat epididymis is modulated by steroid hormones Reproduction. 2010 Mar; 139(3):613-21. . View in PubMed

SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states Cardiovasc Res. 2009 Oct 01; 84(1):111-8. . View in PubMed

AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells Am J Physiol Cell Physiol. 2009 Apr; 296(4):C672-81. . View in PubMed

Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cells J Biol Chem. 2009 Feb 27; 284(9):5774-83. . View in PubMed

Effect of aldosterone on BK channel expression in mammalian cortical collecting duct Am J Physiol Renal Physiol. 2008 Sep; 295(3):F780-8. . View in PubMed

Role of NHERF1, cystic fibrosis transmembrane conductance regulator, and cAMP in the regulation of aquaporin 9 J Biol Chem. 2008 Feb 01; 283(5):2986-96. . View in PubMed

Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells Am J Physiol Cell Physiol. 2008 Feb; 294(2):C488-94. . View in PubMed

Role of acid/base transporters in the male reproductive tract and potential consequences of their malfunction Physiology (Bethesda). 2005 Dec; 20:417-28. . View in PubMed

Stimulation of AQP2 membrane insertion in renal epithelial cells in vitro and in vivo by the cGMP phosphodiesterase inhibitor sildenafil citrate (Viagra) Am J Physiol Renal Physiol. 2005 Jun; 288(6):F1103-12. . View in PubMed

Modulation of the actin cytoskeleton via gelsolin regulates vacuolar H+-ATPase recycling J Biol Chem. 2005 Mar 04; 280(9):8452-63. . View in PubMed

Membrane organization and function of M1 and M23 isoforms of aquaporin-4 in epithelial cells Am J Physiol Renal Physiol. 2004 Sep; 287(3):F501-11. . View in PubMed

Bicarbonate-regulated adenylyl cyclase (sAC) is a sensor that regulates pH-dependent V-ATPase recycling J Biol Chem. 2003 Dec 05; 278(49):49523-9. . View in PubMed

Hypertonicity is involved in redirecting the aquaporin-2 water channel into the basolateral, instead of the apical, plasma membrane of renal epithelial cells J Biol Chem. 2003 Jan 10; 278(2):1101-7. . View in PubMed

Modulation of the onset of postnatal development of H(+)-ATPase-rich cells by steroid hormones in rat epididymis Biol Reprod. 2002 Oct; 67(4):1106-14. . View in PubMed

Expression of aquaporin 9 in the adult rat epididymal epithelium is modulated by androgens Biol Reprod. 2002 Jun; 66(6):1716-22. . View in PubMed

Aquaporin 9 expression along the male reproductive tract Biol Reprod. 2001 Aug; 65(2):384-93. . View in PubMed

Metachromatic leukodystrophy among southern Alaskan Eskimos: molecular and genetic studies J Inherit Metab Dis. 1995; 18(3):326-32. . View in PubMed

Metachromatic leukodystrophy in the Navajo Indian population: a splice site mutation in intron 4 of the arylsulfatase A gene Hum Mutat. 1994; 4(3):199-207. . View in PubMed