Faculty
Eugene Lin
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Interpretable machine learning to evaluate relationships between DAO/DAOA (pLG72) protein data and features in clinical assessments, functional outcome, and cognitive function in schizophrenia patients Schizophrenia (Heidelb). 2025 Feb 22; 11(1):27. . View in PubMed
Light modulates glucose and lipid homeostasis via the sympathetic nervous system Sci Adv. 2024 Dec 13; 10(50):eadp3284. . View in PubMed
Association of Kidney Function With Inpatient Mortality and Morbidity After Cardiac Surgery Ann Thorac Surg Short Rep. 2024 Dec; 2(4):877-883. . View in PubMed
Examining chronic kidney disease screening frequency among diabetics: a POMDP approach Health Care Manag Sci. 2024 Sep; 27(3):391-414. . View in PubMed
Inference of social cognition in schizophrenia patients with neurocognitive domains and neurocognitive tests using automated machine learning Asian J Psychiatr. 2024 Jan; 91:103866. . View in PubMed
Cataract Surgery in the Medicare Merit-Based Incentive Payment System: Episode-Based Cost Measure Development and Evaluation Ophthalmol Sci. 2023 Dec; 3(4):100315. . View in PubMed
Disparities in the Timing of Preoperative Hemodialysis Among Patients With End-Stage Kidney Disease JAMA Netw Open. 2023 07 03; 6(7):e2326326. . View in PubMed
Nephrology and the US News and World Report Hospital-Based Specialty Rankings Kidney Med. 2023 Apr; 5(4):100620. . View in PubMed
Preoperative Hemodialysis Timing and Postoperative Mortality in Patients With End-stage Kidney Disease-Reply JAMA. 2023 03 21; 329(11):939-940. . View in PubMed
J Am Soc Nephrol. 2023 02 01; 34(2):193-194. . View in PubMed
The New Kidney-Focused Companies: A Privatized Approach to Value-Based Care and Addressing Social Determinants of Health J Am Soc Nephrol. 2023 01 01; 34(1):17-20. . View in PubMed
A Blueprint for Assessing Affordability of SGLT2 Inhibitors in the United States: The Cost-Effectiveness of Dapagliflozin in Three European Countries Clin J Am Soc Nephrol. 2022 12; 17(12):1707-1709. . View in PubMed
APOL1 Genotype, Proteinuria, and the Risk of Kidney Failure: A Secondary Analysis of the AASK (African American Study of Kidney Disease and Hypertension) and CRIC (Chronic Renal Insufficiency Cohort) Studies Kidney Med. 2022 Dec; 4(12):100563. . View in PubMed
Association Between Nephrologist Ownership of Dialysis Facilities and Clinical Outcomes JAMA Intern Med. 2022 12 01; 182(12):1267-1276. . View in PubMed
Racial disparities and standard treatment in locally advanced rectal cancer: a National Cancer Database study J Gastrointest Oncol. 2022 Dec; 13(6):2922-2937. . View in PubMed
Association Between Preoperative Hemodialysis Timing and Postoperative Mortality in Patients With End-stage Kidney Disease JAMA. 2022 11 08; 328(18):1837-1848. . View in PubMed
Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions Nat Rev Nephrol. 2022 11; 18(11):724-737. . View in PubMed
Author Correction: Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions Nat Rev Nephrol. 2022 Nov; 18(11):738. . View in PubMed
J Am Soc Nephrol. 2022 11 01; 33(11):1963-1965. . View in PubMed
Medicare Advantage Plans Pay Large Markups To Consolidated Dialysis Organizations Health Aff (Millwood). 2022 08; 41(8):1107-1116. . View in PubMed
Patient Frailty and Functional Use of Hemodialysis Vascular Access: A Retrospective Study of the US Renal Data System Am J Kidney Dis. 2022 07; 80(1):30-45. . View in PubMed
Time to Invest in the Future: Assessing the Cost-Effectiveness of Empagliflozin in Diabetic Kidney Disease Am J Kidney Dis. 2022 06; 79(6):780-782. . View in PubMed
A bagging ensemble machine learning framework to predict overall cognitive function of schizophrenia patients with cognitive domains and tests Asian J Psychiatr. 2022 Mar; 69:103008. . View in PubMed
De Novo Peptide and Protein Design Using Generative Adversarial Networks: An Update J Chem Inf Model. 2022 02 28; 62(4):761-774. . View in PubMed
Logistic ridge regression to predict bipolar disorder using mRNA expression levels in the N-methyl-D-aspartate receptor genes J Affect Disord. 2022 01 15; 297:309-313. . View in PubMed
Health Policy Trends in Kidney Disease Adv Chronic Kidney Dis. 2022 01; 29(1):3-4. . View in PubMed
Machine Learning and Deep Learning for the Pharmacogenomics of Antidepressant Treatments Clin Psychopharmacol Neurosci. 2021 Nov 30; 19(4):577-588. . View in PubMed
Challenging Assumptions of Outcomes and Costs Comparing Peritoneal and Hemodialysis Value Health. 2021 11; 24(11):1592-1602. . View in PubMed
Acral lentiginous melanoma-Population, treatment, and survival using the NCDB from 2004 to 2015 Pigment Cell Melanoma Res. 2021 11; 34(6):1049-1061. . View in PubMed
Deep Learning with Neuroimaging and Genomics in Alzheimer's Disease Int J Mol Sci. 2021 Jul 24; 22(15). . View in PubMed
Prediction of functional outcomes of schizophrenia with genetic biomarkers using a bagging ensemble machine learning method with feature selection Sci Rep. 2021 05 13; 11(1):10179. . View in PubMed
Payment for Dialysis Services in the Individual Market JAMA Intern Med. 2021 05 01; 181(5):698-699. . View in PubMed
Applying a bagging ensemble machine learning approach to predict functional outcome of schizophrenia with clinical symptoms and cognitive functions Sci Rep. 2021 03 25; 11(1):6922. . View in PubMed
Development of the Elective Outpatient Percutaneous Coronary Intervention Episode-Based Cost Measure Circ Cardiovasc Qual Outcomes. 2021 03; 14(3):e006461. . View in PubMed
The Cost of Transferring Dialysis Care From the Employer-Based Market to Medicare JAMA Netw Open. 2021 03 01; 4(3):e212113. . View in PubMed
Racial disparities in receipt of standard chemoradiation in anal squamous cell carcinoma, an analysis of the National Cancer Database Cancer Med. 2021 01; 10(2):575-585. . View in PubMed
What the Comprehensive ESRD Care Program Tells Us About the Advancing American Kidney Health Initiative Am J Kidney Dis. 2020 12; 76(6):893-895. . View in PubMed
Hospitalizations among adults with chronic kidney disease in the United States: A cohort study PLoS Med. 2020 12; 17(12):e1003470. . View in PubMed
The "Advancing American Kidney Health" Executive Order: Challenges and Opportunities for the Large Dialysis Organizations Am J Kidney Dis. 2020 11; 76(5):731-734. . View in PubMed
Policy and Pandemic: The Changing Practice of Nephrology During the Coronavirus Disease-2019 Outbreak Adv Chronic Kidney Dis. 2020 09; 27(5):390-396. . View in PubMed
Payer Mix Among Patients Receiving Dialysis JAMA. 2020 09 01; 324(9):900-901. . View in PubMed
Relevant Applications of Generative Adversarial Networks in Drug Design and Discovery: Molecular De Novo Design, Dimensionality Reduction, and De Novo Peptide and Protein Design Molecules. 2020 Jul 16; 25(14). . View in PubMed
Early Delays in Insurance Coverage and Long-term Use of Home-based Peritoneal Dialysis Med Care. 2020 07; 58(7):632-642. . View in PubMed
Precision Psychiatry Applications with Pharmacogenomics: Artificial Intelligence and Machine Learning Approaches Int J Mol Sci. 2020 Feb 01; 21(3). . View in PubMed
Competing with a pandemic: Trends in research design in a time of Covid-19 PLoS One. 2020; 15(9):e0238831. . View in PubMed
The dialysis care-policy issue: Guest Editors' introductory remarks Semin Dial. 2020 01; 33(1):4. . View in PubMed
Four years into MACRA: What has changed? Semin Dial. 2020 01; 33(1):26-34.. View in PubMed
An Ensemble Approach to Predict Schizophrenia Using Protein Data in the N-methyl-D-Aspartate Receptor (NMDAR) and Tryptophan Catabolic Pathways Front Bioeng Biotechnol. 2020; 8:569. . View in PubMed
Conflicts of interest in dialysis: A barrier to policy reforms Semin Dial. 2020 01; 33(1):83-89. . View in PubMed
Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging in old adults in a Taiwanese population DNA Repair (Amst). 2019 06; 78:1-6. . View in PubMed
Calcimimetics and Bundled Reimbursement Am J Kidney Dis. 2019 03; 73(3):385-390. . View in PubMed
Prior Hospitalization Burden and the Relatedness of 30-Day Readmissions in Patients Receiving Hemodialysis J Am Soc Nephrol. 2019 02; 30(2):323-335. . View in PubMed
Health Insurance in the First 3 Months of Hemodialysis and Early Vascular Access Clin J Am Soc Nephrol. 2018 12 07; 13(12):1866-1875. . View in PubMed
Addressing Financial Disincentives to Improve CKD Care J Am Soc Nephrol. 2018 11; 29(11):2610-2612. . View in PubMed
Palliative Care Disincentives in CKD: Changing Policy to Improve CKD Care Am J Kidney Dis. 2018 06; 71(6):866-873. . View in PubMed
Development of a Radiation Oncology Resident Continuity Clinic to Improve Clinical Competency and Patient Compliance Int J Radiat Oncol Biol Phys. 2018 03 01; 100(3):551-555. . View in PubMed
Cost-effectiveness of multidisciplinary care in mild to moderate chronic kidney disease in the United States: A modeling study PLoS Med. 2018 03; 15(3):e1002532. . View in PubMed
Combination of G72 Genetic Variation and G72 Protein Level to Detect Schizophrenia: Machine Learning Approaches Front Psychiatry. 2018; 9:566. . View in PubMed
Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population Oncotarget. 2017 Nov 07; 8(55):93349-93359. . View in PubMed
Transforming growth factor-ß signaling pathway-associated genes SMAD2 and TGFBR2 are implicated in metabolic syndrome in a Taiwanese population Sci Rep. 2017 10 19; 7(1):13589. . View in PubMed
Home Dialysis in the Prospective Payment System Era J Am Soc Nephrol. 2017 Oct; 28(10):2993-3004. . View in PubMed
The Medicare Access and CHIP Reauthorization Act: Implications for Nephrology J Am Soc Nephrol. 2017 Sep; 28(9):2590-2596. . View in PubMed
Re-evaluation of re-hospitalization and rehabilitation in renal research Hemodial Int. 2017 07; 21(3):422-429. . View in PubMed
Effects of circadian clock genes and environmental factors on cognitive aging in old adults in a Taiwanese population Oncotarget. 2017 Apr 11; 8(15):24088-24098. . View in PubMed
Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population Oncotarget. 2017 Apr 11; 8(15):24077-24087. . View in PubMed
Genetic Biomarkers on Age-Related Cognitive Decline Front Psychiatry. 2017; 8:247. . View in PubMed
Machine learning and systems genomics approaches for multi-omics data Biomark Res. 2017; 5:2. . View in PubMed
The ADAMTS9 gene is associated with cognitive aging in the elderly in a Taiwanese population PLoS One. 2017; 12(2):e0172440. . View in PubMed
Effects of circadian clock genes and health-related behavior on metabolic syndrome in a Taiwanese population: Evidence from association and interaction analysis PLoS One. 2017; 12(3):e0173861. . View in PubMed
Association and interaction of APOA5, BUD13, CETP, LIPA and health-related behavior with metabolic syndrome in a Taiwanese population Sci Rep. 2016 11 09; 6:36830. . View in PubMed
Genome-wide microarray analysis of gene expression profiling in major depression and antidepressant therapy Prog Neuropsychopharmacol Biol Psychiatry. 2016 Jan 04; 64:334-40. . View in PubMed
Genome-wide association studies in pharmacogenomics of antidepressants Pharmacogenomics. 2015; 16(5):555-66. . View in PubMed
Highlights from the latest articles in pharmacogenomics of antipsychotics Pharmacogenomics. 2014 Mar; 15(4):415-7. . View in PubMed
Evaluation of the glutamine 27 glutamic acid polymorphism in the adrenoceptor ß2 surface gene on obesity and metabolic phenotypes in Taiwan J Investig Med. 2014 Feb; 62(2):310-5. . View in PubMed
Early rehospitalization after kidney transplantation: assessing preventability and prognosis Am J Transplant. 2013 Dec; 13(12):3164-72. . View in PubMed
Research Highlights: Genetic association of the dopamine receptor D3 Ser9Gly polymorphism with a DRD3 antagonist Per Med. 2013 Sep; 10(7):631-632. . View in PubMed
Assessing gene-gene interactions in pharmacogenomics Mol Diagn Ther. 2012 Feb 01; 16(1):15-27. . View in PubMed
Overtreatment of enterococcal bacteriuria Arch Intern Med. 2012 Jan 09; 172(1):33-8. . View in PubMed
Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease FASEB J. 2011 May; 25(5):1653-63. . View in PubMed
Research highlights from the latest articles in 5-HTTLPR pharmacogenomics Per Med. 2010 Mar; 7(2):139-141. . View in PubMed
Association and interaction analyses of genetic variants in ADIPOQ, ENPP1, GHSR, PPARgamma and TCF7L2 genes for diabetic nephropathy in a Taiwanese population with type 2 diabetes Nephrol Dial Transplant. 2009 Nov; 24(11):3360-6. . View in PubMed
A comparison of classification methods for predicting Chronic Fatigue Syndrome based on genetic data J Transl Med. 2009 Sep 22; 7:81. . View in PubMed
Gene-gene interactions among genetic variants from obesity candidate genes for nonobese and obese populations in type 2 diabetes Genet Test Mol Biomarkers. 2009 Aug; 13(4):485-93. . View in PubMed
A Bayesian approach to gene-gene and gene-environment interactions in chronic fatigue syndrome Pharmacogenomics. 2009 Jan; 10(1):35-42. . View in PubMed
Pharmacogenomics with antidepressants in the STAR*D study Pharmacogenomics. 2008 Jul; 9(7):935-46. . View in PubMed
A support vector machine approach to assess drug efficacy of interferon-alpha and ribavirin combination therapy Mol Diagn Ther. 2008; 12(4):219-23. . View in PubMed
Association study of a brain-derived neurotrophic-factor polymorphism and short-term antidepressant response in major depressive disorders Pharmgenomics Pers Med. 2008; 1:1-6. . View in PubMed
Identification of significant genes in genomics using Bayesian variable selection methods Adv Appl Bioinform Chem. 2008; 1:13-8. . View in PubMed
Gene-gene and gene-environment interactions in interferon therapy for chronic hepatitis C Pharmacogenomics. 2007 Oct; 8(10):1327-35. . View in PubMed
Pattern-recognition techniques with haplotype analysis in pharmacogenomics Pharmacogenomics. 2007 Jan; 8(1):75-83. . View in PubMed
An artificial neural network approach to the drug efficacy of interferon treatments Pharmacogenomics. 2006 Oct; 7(7):1017-24. . View in PubMed
A case study of the utility of the HapMap database for pharmacogenomic haplotype analysis in the Taiwanese population Mol Diagn Ther. 2006; 10(6):367-70. . View in PubMed
Bacteria in the treatment of cancer Curr Opin Mol Ther. 2004 Dec; 6(6):629-39. . View in PubMed
Oncolytic viral therapies Cancer Gene Ther. 2004 Oct; 11(10):643-64. . View in PubMed
In addition to his role as an Assistant Professor of Medicine in the Division of Nephrology & Hypertension, he is also a Clinical and Resident Fellow at the Leonard D. Schaeffer Center for Health Policy & Economics.
Dr. Lin is a nationally recognized expert on payment policy and currently serves on the National Kidney Foundation’s Scientific Advisory Board and the American Society of Nephrology’s Transplant Policy Committee. He has previously served on the ASN's Quality and Policy and Advocacy Committees. He has participated as a key stakeholder in multiple Technical Expert Panels for the Centers for Medicare and Medicaid Services.
Dr. Lin completed a postdoctoral fellowship in nephrology at the Stanford School of Medicine and completed his Internal Medicine residency at the Hospital of the University of Pennsylvania.
He is an NIH funded investigator, and his work has been published in leading health policy and medical journals, including JAMA, Health Affairs, and JAMA Internal Medicine.