Faculty
Alicia A. McDonough
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American Heart Association Hypertension Council: Irvine Page & Alba Bradley Lifetime Achievement Award, 2022
International Union of Physiological Scientists: Robert Pitts Awardee, 2022
Case Western School of Medicine: Ulrich Hopfer Lectureship, 2019
American Physiological Society Epithelial Transport Group: Steve Hebert Lecturer, 2018
University of Southern California: Phi Kappa Phi Faculty Recognition Award, 2018
American Society of Nephrology: Robert W. Schrier Endowed Lectureship, 2017
Medical College of Wisconsin: J.J. Smith Endowed Lecture, 2016
American Heart Association KCVD Young Investigator Symposium: Keynote Speaker ASN Kidney Week, 2016
Kansas State Univ. Veterinary Medicine: Clarenberg Distinguished Lecture, 2015
American Heart Association Kidney in Cardiovascular Disease Council: Donald Seldin Lecture, 2014
SUNY Buffalo: Suk Ki Hong Memorial Lecturer, 2010
American Physiological Society: Ernest H. Starling Distinguished Lectureship, 2009
Keck School of Medicine: Outstanding Teaching Awards: '07, '12, '17, 2007-2018
American Heart Association: Established Investigator Award, 1984-1989
Kinetic Modeling of In Vivo K+ Distribution and Fluxes with Stable K+ Isotopes: Effects of Dietary K+ Restriction Int J Mol Sci. 2024 Sep 06; 25(17). . View in PubMed
Optimizing Renal Transporter Immunodetection: Consequences of Freeze-Thaw during Sample Preparation Am J Physiol Renal Physiol. 2024 Aug 29. . View in PubMed
Potassium-Alkali-Enriched Diet, Hypertension, and Proteinuria following Uninephrectomy J Am Soc Nephrol. 2024 Jun 24. . View in PubMed
Angiotensin II Directly Increases Endothelial Calcium and Nitric Oxide in Kidney and Brain Microvessels In Vivo With Reduced Efficacy in Hypertension J Am Heart Assoc. 2024 May 21; 13(10):e033998. . View in PubMed
Sex differences in renal transporters: assessment and functional consequences Nat Rev Nephrol. 2024 01; 20(1):21-36. . View in PubMed
Our Editorial Fellowship Program: Building Synergism J Am Soc Nephrol. 2023 12 01; 34(12):1940-1943. . View in PubMed
Sex differences in renal electrolyte transport Curr Opin Nephrol Hypertens. 2023 09 01; 32(5):467-475. . View in PubMed
Angiotensin II hypertension along the female rat tubule: predicted impact on coupled transport of Na+ and K Am J Physiol Renal Physiol. 2023 12 01; 325(6):F733-F749. . View in PubMed
The Highs and Lows of Potassium Intake in CKD-Does One Size Fit All? J Am Soc Nephrol. 2022 09; 33(9):1638-1640.. View in PubMed
Potassium homeostasis: sensors, mediators, and targets Pflugers Arch. 2022 08; 474(8):853-867. . View in PubMed
Estimating in vivo potassium distribution and fluxes with stable potassium isotopes Am J Physiol Cell Physiol. 2022 03 01; 322(3):C410-C420. . View in PubMed
Stable potassium isotopes (41K/39K) track transcellular and paracellular potassium transport in biological systems Front Physiol. 2022; 13:1016242. . View in PubMed
Cell-Specific Actions of the Prostaglandin E-Prostanoid Receptor 4 Attenuating Hypertension: A Dominant Role for Kidney Epithelial Cells Compared With Macrophages J Am Heart Assoc. 2022 10 04; 11(19):e026581. . View in PubMed
Sex differences in solute and water handling in the human kidney: Modeling and functional implications iScience. 2021 Jun 25; 24(6):102667. . View in PubMed
Impact of casein- versus grain-based diets on rat renal sodium transporters' abundance and regulation Kidney360. 2021 03; 2(3):519-523. . View in PubMed
Vascular control of kidney epithelial transporters Am J Physiol Renal Physiol. 2021 06 01; 320(6):F1080-F1092. . View in PubMed
Sex-specific adaptations to high-salt diet preserve electrolyte homeostasis with distinct sodium transporter profiles Am J Physiol Cell Physiol. 2021 11 01; 321(5):C897-C909. . View in PubMed
Local and downstream actions of proximal tubule angiotensin II signaling on Na+ transporters in the mouse nephron Am J Physiol Renal Physiol. 2021 07 01; 321(1):F69-F81. . View in PubMed
Electrolyte and transporter responses to angiotensin II induced hypertension in female and male rats and mice Acta Physiol (Oxf). 2020 05; 229(1):e13448. . View in PubMed
a2A-Adrenoceptors Modulate Renal Sympathetic Neurotransmission and Protect against Hypertensive Kidney Disease J Am Soc Nephrol. 2020 04; 31(4):783-798. . View in PubMed
Report of the National Heart, Lung, and Blood Institute Working Group on Hypertension: Barriers to Translation Hypertension. 2020 04; 75(4):902-917. . View in PubMed
Sex differences in solute transport along the nephrons: effects of Na+ transport inhibition Am J Physiol Renal Physiol. 2020 09 01; 319(3):F487-F505. . View in PubMed
Coordinate adaptations of skeletal muscle and kidney to maintain extracellular [K+] during K+-deficient diet Am J Physiol Cell Physiol. 2020 10 01; 319(4):C757-C770. . View in PubMed
Moving the Needle on Hypertension: What Knowledge Is Needed? Nutr Today. 2019 Nov-Dec; 54(6):248-256.. View in PubMed
Functional implications of the sex differences in transporter abundance along the rat nephron: modeling and analysis Am J Physiol Renal Physiol. 2019 12 01; 317(6):F1462-F1474. . View in PubMed
Impact of angiotensin II-mediated stimulation of sodium transporters in the nephron assessed by computational modeling Am J Physiol Renal Physiol. 2019 12 01; 317(6):F1656-F1668. . View in PubMed
The Absence of the ACE N-Domain Decreases Renal Inflammation and Facilitates Sodium Excretion during Diabetic Kidney Disease J Am Soc Nephrol. 2018 10; 29(10):2546-2561. . View in PubMed
Blood pressure regulation by the angiotensin type 1 receptor in the proximal tubule Curr Opin Nephrol Hypertens. 2018 01; 27(1):1-7. . View in PubMed
Functional implications of sexual dimorphism of transporter patterns along the rat proximal tubule: modeling and analysis Am J Physiol Renal Physiol. 2018 09 01; 315(3):F692-F700. . View in PubMed
Downregulation of the Cl-/HCO3-Exchanger Pendrin in Kidneys of Mice with Cystic Fibrosis: Role in the Pathogenesis of Metabolic Alkalosis Cell Physiol Biochem. 2018; 45(4):1551-1565. . View in PubMed
Sexual Dimorphic Pattern of Renal Transporters and Electrolyte Homeostasis J Am Soc Nephrol. 2017 Dec; 28(12):3504-3517. . View in PubMed
Collecting duct prorenin receptor knockout reduces renal function, increases sodium excretion, and mitigates renal responses in ANG II-induced hypertensive mice Am J Physiol Renal Physiol. 2017 Dec 01; 313(6):F1243-F1253. . View in PubMed
Collecting Duct Nitric Oxide Synthase 1ß Activation Maintains Sodium Homeostasis During High Sodium Intake Through Suppression of Aldosterone and Renal Angiotensin II Pathways J Am Heart Assoc. 2017 Oct 24; 6(10). . View in PubMed
Renal Collectrin Protects against Salt-Sensitive Hypertension and Is Downregulated by Angiotensin II J Am Soc Nephrol. 2017 Jun; 28(6):1826-1837. . View in PubMed
Renal tubular angiotensin converting enzyme is responsible for nitro-L-arginine methyl ester (L-NAME)-induced salt sensitivity Kidney Int. 2017 04; 91(4):856-867. . View in PubMed
Potassium Homeostasis: The Knowns, the Unknowns, and the Health Benefits Physiology (Bethesda). 2017 03; 32(2):100-111. . View in PubMed
Cardiovascular benefits associated with higher dietary K+ vslower dietary Na+: evidence from population and mechanistic studies. Am J Physiol Endocrinol Metab. 2017 04 01; 312(4):E348-E356. . View in PubMed
ISN Forefronts Symposium 2015: Maintaining Balance Under Pressure-Hypertension and the Proximal Tubule Kidney Int Rep. 2016 Sep; 1(3):166-176. . View in PubMed
Interleukin-1 Receptor Activation Potentiates Salt Reabsorption in Angiotensin II-Induced Hypertension via the NKCC2 Co-transporter in the Nephron Cell Metab. 2016 Feb 09; 23(2):360-8. . View in PubMed
The physiological role of glucagon-like peptide-1 in the regulation of renal function Am J Physiol Renal Physiol. 2016 Jan 15; 310(2):F123-7. . View in PubMed
Potassium Supplementation Prevents Sodium Chloride Cotransporter Stimulation During Angiotensin II Hypertension Hypertension. 2016 10; 68(4):904-12. . View in PubMed
Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hypertension Hypertension. 2016 07; 68(1):167-74. . View in PubMed
Paracellular epithelial sodium transport maximizes energy efficiency in the kidney J Clin Invest. 2016 07 01; 126(7):2509-18. . View in PubMed
Proximal tubule NHE3 activity is inhibited by beta-arrestin-biased angiotensin II type 1 receptor signaling Am J Physiol Cell Physiol. 2015 Oct 15; 309(8):C541-50. . View in PubMed
Maintaining Balance Under Pressure: Integrated Regulation of Renal Transporters During Hypertension Hypertension. 2015 Sep; 66(3):450-5. . View in PubMed
Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Converting Enzyme Hypertension. 2015 Sep; 66(3):534-42. . View in PubMed
Short-term nonpressor angiotensin II infusion stimulates sodium transporters in proximal tubule and distal nephron Physiol Rep. 2015 Sep; 3(9). . View in PubMed
Renal NCC is unchanged in the midpregnant rat and decreased in the late pregnant rat despite avid renal Na+ retention Am J Physiol Renal Physiol. 2015 Jul 01; 309(1):F63-70. . View in PubMed
The intrarenal generation of angiotensin II is required for experimental hypertension Curr Opin Pharmacol. 2015 Apr; 21:73-81. . View in PubMed
Considerations when quantitating protein abundance by immunoblot Am J Physiol Cell Physiol. 2015 Mar 15; 308(6):C426-33. . View in PubMed
Hypertension. 2015 Mar; 65(3):569-76. . View in PubMed
Renal angiotensin-converting enzyme is essential for the hypertension induced by nitric oxide synthesis inhibition J Am Soc Nephrol. 2014 Dec; 25(12):2752-63. . View in PubMed
Am J Physiol Renal Physiol. 2014 Dec 01; 307(11):F1249-62. . View in PubMed
Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K-ATPase, FXYD2 Physiol Rep. 2014 Dec 01; 2(12). . View in PubMed
Of mice and men: modeling cardiovascular complexity in diabetesFocus on "Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart". Am J Physiol Cell Physiol. 2014 Sep 15; 307(6):C497-8. . View in PubMed
Renal generation of angiotensin II and the pathogenesis of hypertension Curr Hypertens Rep. 2014 Sep; 16(9):477. . View in PubMed
Increasing plasma [K+] by intravenous potassium infusion reduces NCC phosphorylation and drives kaliuresis and natriuresis Am J Physiol Renal Physiol. 2014 May 01; 306(9):F1059-68. . View in PubMed
Compression injury in the mouse spinal cord elicits a specific proliferative response and distinct cell fate acquisition along rostro-caudal and dorso-ventral axes Neuroscience. 2013 Dec 19; 254:1-17. . View in PubMed
Differential regulation of Na+ transporters along nephron during ANG II-dependent hypertension: distal stimulation counteracted by proximal inhibition Am J Physiol Renal Physiol. 2013 Aug 15; 305(4):F510-9. . View in PubMed
J Mol Med (Berl). 2013 Aug; 91(8):951-63. . View in PubMed
Need to quickly excrete K(+)? Turn off NCC. Kidney Int. 2013 May; 83(5):779-82.. View in PubMed
The absence of intrarenal ACE protects against hypertension J Clin Invest. 2013 May; 123(5):2011-23. . View in PubMed
Effects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties Am J Physiol Cell Physiol. 2013 Jan 15; 304(2):C147-63. . View in PubMed
Effects of K+-deficient diets with and without NaCl supplementation on Na+, K+, and H2O transporters' abundance along the nephron Am J Physiol Renal Physiol. 2012 Jul 01; 303(1):F92-104. . View in PubMed
Am J Physiol Cell Physiol. 2012 May 15; 302(10):C1434-5. . View in PubMed
How does potassium supplementation lower blood pressure? Am J Physiol Renal Physiol. 2012 May 01; 302(9):F1224-5.. View in PubMed
AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure Cell Metab. 2011 Apr 06; 13(4):469-475. . View in PubMed
Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressure Am J Physiol Regul Integr Comp Physiol. 2010 Apr; 298(4):R851-61. . View in PubMed
Angiotensin II stimulates trafficking of NHE3, NaPi2, and associated proteins into the proximal tubule microvilli Am J Physiol Renal Physiol. 2010 Jan; 298(1):F177-86. . View in PubMed
Motoring down the microvilliFocus on "PTH-induced internalization of apical membrane NaPi2a: role of actin and myosin VI". Am J Physiol Cell Physiol. 2009 Dec; 297(6):C1331-2. . View in PubMed
Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1 Eur J Pharmacol. 2009 Nov 10; 622(1-3):7-14. . View in PubMed
Narrative review: evolving concepts in potassium homeostasis and hypokalemia Ann Intern Med. 2009 May 05; 150(9):619-25. . View in PubMed
Acute hypertension provokes acute trafficking of distal tubule Na-Cl cotransporter (NCC) to subapical cytoplasmic vesicles Am J Physiol Renal Physiol. 2009 Apr; 296(4):F810-8. . View in PubMed
Renal NHE3 and NaPi2 partition into distinct membrane domains Am J Physiol Cell Physiol. 2009 Apr; 296(4):C900-10. . View in PubMed
Recent advances in understanding integrative control of potassium homeostasis Annu Rev Physiol. 2009; 71:381-401. . View in PubMed
Effects of dietary salt on renal Na+ transporter subcellular distribution, abundance, and phosphorylation status Am J Physiol Renal Physiol. 2008 Oct; 295(4):F1003-16. . View in PubMed
Rationale and design of CAPITA: a RCT of 13-valent conjugated pneumococcal vaccine efficacy among older adults Neth J Med. 2008 Oct; 66(9):378-83. . View in PubMed
Connexin 303 is expressed in the kidney but not regulated by dietary salt or high blood pressure. Cell Commun Adhes. 2008 May; 15(1):219-30. . View in PubMed
AMPK activation with AICAR provokes an acute fall in plasma [K+] Am J Physiol Cell Physiol. 2008 Jan; 294(1):C126-35. . View in PubMed
Slc26a6 (PAT1) deletion downregulates the apical Na+/H+ exchanger in the straight segment of the proximal tubule Am J Nephrol. 2008; 28(2):330-8. . View in PubMed
Reducing blood pressure in SHR with enalapril provokes redistribution of NHE3, NaPi2, and NCC and decreases NaPi2 and ACE abundance Am J Physiol Renal Physiol. 2007 Oct; 293(4):F1197-208. . View in PubMed
ANG II provokes acute trafficking of distal tubule Na+-Cl(-) cotransporter to apical membrane Am J Physiol Renal Physiol. 2007 Sep; 293(3):F662-9. . View in PubMed
Evidence for gut factor in K+ homeostasis Am J Physiol Renal Physiol. 2007 Aug; 293(2):F541-7. . View in PubMed
Redistribution of distal tubule Na+-Cl- cotransporter (NCC) in response to a high-salt diet Am J Physiol Renal Physiol. 2006 Aug; 291(2):F503-8. . View in PubMed
The proximal convoluted tubule is a target for the uroguanylin-regulated natriuretic response J Pediatr Gastroenterol Nutr. 2006 Jul; 43 Suppl 1:S74-81. . View in PubMed
Phenol injury-induced hypertension stimulates proximal tubule Na+/H+ exchanger activity Am J Physiol Renal Physiol. 2006 Jun; 290(6):F1543-50. . View in PubMed
Modest dietary K+ restriction provokes insulin resistance of cellular K+ uptake and phosphorylation of renal outer medulla K+ channel without fall in plasma K+ concentration Am J Physiol Cell Physiol. 2006 May; 290(5):C1355-63. . View in PubMed
Effects of ACE inhibition on proximal tubule sodium transport Am J Physiol Renal Physiol. 2006 Apr; 290(4):F854-63. . View in PubMed
Redistribution of myosin VI from top to base of proximal tubule microvilli during acute hypertension J Am Soc Nephrol. 2005 Oct; 16(10):2890-6. . View in PubMed
Role of muscle in regulating extracellular [K+] Semin Nephrol. 2005 Sep; 25(5):335-42. . View in PubMed
Differential traffic of proximal tubule Na+ transporters during hypertension or PTH: NHE3 to base of microvilli vsNaPi2 to endosomes. Am J Physiol Renal Physiol. 2004 Nov; 287(5):F896-906. . View in PubMed
Dexamethasone treatment causes resistance to insulin-stimulated cellular potassium uptake in the rat Am J Physiol Cell Physiol. 2004 Nov; 287(5):C1229-37. . View in PubMed
Acute hypotension induced by aortic clamp vsPTH provokes distinct proximal tubule Na+ transporter redistribution patterns. Am J Physiol Regul Integr Comp Physiol. 2004 Oct; 287(4):R878-85. . View in PubMed
Does membrane trafficking play a role in regulating the sodium/hydrogen exchanger isoform 3 in the proximal tubule? Curr Opin Nephrol Hypertens. 2003 Sep; 12(5):533-41.. View in PubMed
Chronic renal injury-induced hypertension alters renal NHE3 distribution and abundance Am J Physiol Renal Physiol. 2003 May; 284(5):F1056-65. . View in PubMed
Mechanisms of pressure natriuresis: how blood pressure regulates renal sodium transport Ann N Y Acad Sci. 2003 Apr; 986:669-77. . View in PubMed
Modest K+ restriction provokes insulin resistance of cellular K+ uptake without decrease in plasma K Ann N Y Acad Sci. 2003 Apr; 986:625-7. . View in PubMed
Responses of proximal tubule sodium transporters to acute injury-induced hypertension Am J Physiol Renal Physiol. 2003 Feb; 284(2):F313-22. . View in PubMed
Angiotensin II clamp prevents the second step in renal apical NHE3 internalization during acute hypertension Am J Physiol Renal Physiol. 2002 Nov; 283(5):F1142-50. . View in PubMed
Diuretic response to acute hypertension is blunted during angiotensin II clamp Am J Physiol Regul Integr Comp Physiol. 2002 Oct; 283(4):R837-42. . View in PubMed
Skeletal muscle regulates extracellular potassium Am J Physiol Renal Physiol. 2002 Jun; 282(6):F967-74. . View in PubMed
Independent regulation of in vivo insulin action on glucose versus K(+) uptake by dietary fat and K(+) content Diabetes. 2002 Apr; 51(4):915-20. . View in PubMed
Acute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activity Am J Physiol Renal Physiol. 2002 Apr; 282(4):F730-40. . View in PubMed
The cardiac sodium pump: structure and function Basic Res Cardiol. 2002; 97 Suppl 1:I19-24. . View in PubMed
Sodium pump isoform expression in heart failure: implication for treatment Basic Res Cardiol. 2002; 97 Suppl 1:I25-30. . View in PubMed
Downstream shift in sodium pump activity along the nephron during acute hypertension J Am Soc Nephrol. 2001 Nov; 12(11):2231-2240. . View in PubMed
All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides Am J Physiol Cell Physiol. 2001 Oct; 281(4):C1336-43. . View in PubMed
Ouabain and substrate affinities of human Na(+)-K(+)-ATPase alpha(1)beta(1), alpha(2)beta(1), and alpha(3)beta(1) when expressed separately in yeast cells Am J Physiol Cell Physiol. 2001 Oct; 281(4):C1355-64. . View in PubMed
UT-A urea transporter protein in heart: increased abundance during uremia, hypertension, and heart failure Circ Res. 2001 Jul 20; 89(2):139-45. . View in PubMed
Glucocorticoids increase sodium pump alpha(2)- and beta(1)-subunit abundance and mRNA in rat skeletal muscle Am J Physiol Cell Physiol. 2001 Mar; 280(3):C509-16. . View in PubMed
Region specific regulation of sodium pump isoform and Na,Ca-exchanger expression in the failing human heart--right atrium vs left ventricle Cell Mol Biol (Noisy-le-grand). 2001 Mar; 47(2):373-81. . View in PubMed
Short-term K(+) deprivation provokes insulin resistance of cellular K(+) uptake revealed with the K(+) clamp Am J Physiol Renal Physiol. 2001 Jan; 280(1):F95-F102. . View in PubMed
Proximal tubule Na transporter responses are the same during acute and chronic hypertension Am J Physiol Renal Physiol. 2000 Aug; 279(2):F358-69. . View in PubMed
Developmental change in Na,K-ATPase alpha1 and beta1 expression in normal and hypothyroid rat renal cortex Am J Nephrol. 2000 May-Jun; 20(3):225-31. . View in PubMed
Molecular mechanisms of sodium transport inhibition in proximal tubule during acute hypertension Curr Opin Nephrol Hypertens. 2000 Mar; 9(2):149-56. . View in PubMed
Reduced sodium pump alpha1, alpha3, and beta1-isoform protein levels and Na+,K+-ATPase activity but unchanged Na+-Ca2+ exchanger protein levels in human heart failure Circulation. 1999 Apr 27; 99(16):2105-12. . View in PubMed
Temporal responses of oxidative vsglycolytic skeletal muscles to K+ deprivation: Na+ pumps and cell cations. Am J Physiol. 1999 06; 276(6):C1411-9. . View in PubMed
In vivo PTH provokes apical NHE3 and NaPi2 redistribution and Na-K-ATPase inhibition Am J Physiol. 1999 05; 276(5):F711-9. . View in PubMed
The cytochrome P-450 inhibitor cobalt chloride prevents inhibition of renal Na,K-ATPase and redistribution of apical NHE-3 during acute hypertension J Am Soc Nephrol. 1998 Apr; 9(4):531-7. . View in PubMed
Am J Physiol. 1998 11; 275(5):C1179-81. . View in PubMed
Redistribution of Na+/H+ exchanger isoform NHE3 in proximal tubules induced by acute and chronic hypertension Am J Physiol. 1998 10; 275(4):F565-75. . View in PubMed
Reversible effects of acute hypertension on proximal tubule sodium transporters Am J Physiol. 1998 04; 274(4):C1090-100. . View in PubMed
Posttranscriptional upregulation of Na(+)-K(+)-ATPase activity in newborn guinea pig renal cortex Am J Physiol. 1997 Aug; 273(2 Pt 2):F254-63. . View in PubMed
Skeletal muscle Na,K-ATPase alpha and beta subunit protein levels respond to hypokalemic challenge with isoform and muscle type specificity J Biol Chem. 1996 Dec 20; 271(51):32653-8. . View in PubMed
Regional expression of sodium pump subunits isoforms and Na+-Ca++ exchanger in the human heart J Clin Invest. 1996 Oct 01; 98(7):1650-8. . View in PubMed
Rapid redistribution and inhibition of renal sodium transporters during acute pressure natriuresis Am J Physiol. 1996 Jun; 270(6 Pt 2):F1004-14. . View in PubMed
Subcellular distribution of sodium pump isoform subunits in mammalian cardiac myocytes Am J Physiol. 1996 Apr; 270(4 Pt 1):C1221-7. . View in PubMed
Role of skeletal muscle sodium pumps in the adaptation to potassium deprivation Acta Physiol Scand. 1996 Mar; 156(3):295-304. . View in PubMed
Renal Na+/H+ exchanger isoforms and their regulation by thyroid hormone Am J Physiol. 1996 Feb; 270(2 Pt 1):C585-92. . View in PubMed
Reciprocal regulation of cardiac Na-K-ATPase and Na/Ca exchanger: hypertension, thyroid hormone, development Am J Physiol. 1995 Sep; 269(3 Pt 1):C675-82. . View in PubMed
Significance of sodium pump isoforms in digitalis therapy J Mol Cell Cardiol. 1995 Apr; 27(4):1001-9. . View in PubMed
Expression of Na(+)-K(+)-ATPase alpha- and beta-subunits along rat nephron: isoform specificity and response to hypokalemia Am J Physiol. 1994 Oct; 267(4 Pt 1):C901-8. . View in PubMed
Amiodarone decreases Na,K-ATPase alpha 2 and beta 2 expression specifically in cardiac ventricle J Mol Cell Cardiol. 1994 Apr; 26(4):417-24. . View in PubMed
Nicotine downregulates alpha 2 isoform of Na,K-ATPase at the blood-brain barrier and brain in rats Biochem Biophys Res Commun. 1994 Mar 30; 199(3):1422-7. . View in PubMed
Surface and intracellular pools of Na,K-ATPase catalytic and immuno-activities in rat exorbital lacrimal gland Exp Eye Res. 1993 Oct; 57(4):403-13. . View in PubMed
Surplus Na+ pumps: how low-K(+)-incubated LLC-PK1 cells respond to K+ restoration Am J Physiol. 1993 Oct; 265(4 Pt 1):C887-92. . View in PubMed
Thyroid hormone specifically regulates skeletal muscle Na(+)-K(+)-ATPase alpha 2- and beta 2-isoforms Am J Physiol. 1993 Sep; 265(3 Pt 1):C680-7. . View in PubMed
Regulation of Na,K-ATPase activity Curr Opin Nephrol Hypertens. 1993 Sep; 2(5):725-34. . View in PubMed
Differential expression of Na,K-ATPase alpha and beta subunit isoforms at the blood-brain barrier and the choroid plexus J Biol Chem. 1993 Apr 15; 268(11):8019-25. . View in PubMed
Na(+)-K(+)-ATPase alpha 1- and beta 1-subunit degradation: evidence for multiple subunit specific rates Am J Physiol. 1993 Mar; 264(3 Pt 1):C583-90. . View in PubMed
Expression of Na,K-ATPase at the blood-brain interface Adv Exp Med Biol. 1993; 331:55-60. . View in PubMed
Physiologic rationale for multiple sodium pump isoformsDifferential regulation of alpha 1 vs alpha 2 by ionic stimuli. Ann N Y Acad Sci. 1992 Nov 30; 671:156-68; discussion 168-9. . View in PubMed
Low K+ increases Na(+)-K(+)-ATPase alpha- and beta-subunit mRNA and protein abundance in cultured renal proximal tubule cells Am J Physiol. 1992 Aug; 263(2 Pt 1):C436-42. . View in PubMed
Synthesis and translocation of Na(+)-K(+)-ATPase alpha- and beta-subunits to plasma membrane in MDCK cells Am J Physiol. 1992 Feb; 262(2 Pt 1):C470-83. . View in PubMed
Thyroid hormone induction of rat myocardial Na(+)-K(+)-ATPase: alpha 1-, alpha 2-, and beta 1-mRNA and -protein levels at steady state Am J Physiol. 1992 Feb; 262(2 Pt 1):C484-92. . View in PubMed
Rapid hypertensinogenic effect of lead: studies in the spontaneously hypertensive rat Toxicol Ind Health. 1992 Jan-Apr; 8(1-2):89-102. . View in PubMed
Differential regulation of sodium pump isoforms in heart Semin Nephrol. 1992 Jan; 12(1):49-55. . View in PubMed
Hypokalemia decreases Na(+)-K(+)-ATPase alpha 2- but not alpha 1-isoform abundance in heart, muscle, and brain Am J Physiol. 1991 May; 260(5 Pt 1):C958-64. . View in PubMed
Regulation of testicular P-450 cholesterol side-chain cleavage and P-450 C17-20 lyase/C17 hydroxylase enzymes in the neonatal and adult rat Acta Endocrinol (Copenh). 1991 Apr; 124(4):449-54. . View in PubMed
Low K+ increases Na,K-ATPase abundance in LLC-PK1/Cl4 cells by differentially increasing beta, and not alpha, subunit mRNA J Biol Chem. 1990 Oct 15; 265(29):17935-40. . View in PubMed
Differential regulation of Na,K-ATPase alpha 1, alpha 2, and beta subunit mRNA and protein levels by thyroid hormone J Biol Chem. 1990 Aug 25; 265(24):14308-14. . View in PubMed
Ionic regulation of the biosynthesis of NaK-ATPase subunits Semin Nephrol. 1990 Jul; 10(4):400-9. . View in PubMed
The sodium pump needs its beta subunit FASEB J. 1990 Apr 01; 4(6):1598-605. . View in PubMed
alar4, a constitutive mutant of the A system for amino acid transport, has increased abundance of the Na+,K+-ATPase and mRNA for alpha 1 subunit of this enzyme Proc Natl Acad Sci U S A. 1989 Oct; 86(20):7984-8. . View in PubMed
Thyroid hormone regulates alpha and alpha + isoforms of Na,K-ATPase during development in neonatal rat brain J Biol Chem. 1988 Nov 25; 263(33):17643-9. . View in PubMed
Patterns of mRNA expression during early cell growth differ in kidney epithelial cells destined to undergo compensatory hypertrophy versus regenerative hyperplasia Proc Natl Acad Sci U S A. 1988 Sep; 85(18):6768-72. . View in PubMed
Thyroid hormone coordinately regulates Na+-K+-ATPase alpha- and beta-subunit mRNA levels in kidney Am J Physiol. 1988 Feb; 254(2 Pt 1):C323-9. . View in PubMed
Isozymes of dog heart Na+-K+-ATPase are immunologically similar to isozymes in brain Am J Physiol. 1987 Dec; 253(6 Pt 1):C862-5. . View in PubMed
Enrichment of Na+-Ca2+ exchange in cardiac sarcolemmal vesicles by alkaline extraction Biochim Biophys Acta. 1987 May 12; 899(1):59-66. . View in PubMed
Molecular cloning and sequence analysis of the (Na+ + K+)-ATPase beta subunit from dog kidney Biochim Biophys Acta. 1987 Apr 08; 912(2):244-53. . View in PubMed
Pretranslational regulation of Na-K-ATPase in cultured canine kidney cells by low K+ Am J Physiol. 1987 Feb; 252(2 Pt 1):C179-89. . View in PubMed
Developmental and thyroid hormone regulation of two molecular forms of Na+-K+-ATPase in brain J Biol Chem. 1986 Aug 05; 261(22):10439-44. . View in PubMed
Isolation of partial cDNAs for rat liver and muscle glycogen phosphorylase isozymes FEBS Lett. 1986 Jul 07; 202(2):282-8. . View in PubMed
Mapping subcellular distribution of Na+-K+-ATPase in rat parotid gland Am J Physiol. 1986 Mar; 250(3 Pt 1):C430-41. . View in PubMed
Immunodetection of Na,K-ATPase in guinea-pig retinal layers, cornea and lens Exp Eye Res. 1985 May; 40(5):667-74. . View in PubMed
Comparison of subunits of cardiac, brain, and kidney Na+-K+-ATPase Am J Physiol. 1985 Mar; 248(3 Pt 1):C247-51. . View in PubMed
Assembly of the (Na+ + K+)-adenosine triphosphatasePost-translational membrane integration of the alpha subunit. J Biol Chem. 1984 Feb 25; 259(4):2629-35. . View in PubMed
Characteristics of antibodies to guinea pig (Na+ + K+)-adenosine triphosphatase and their use in cell-free synthesis studies J Membr Biol. 1982; 69(1):13-22. . View in PubMed
Hana kai ii: a 17-day dry saturation dive at 186 ATA. III. Body fluid balance. Undersea Biomed Res. 1977 Sep; 4(3):247-65. . View in PubMed