Our Team

Faculty

Mark S. Humayun

Mark S. Humayun

University Professor of Ophthalmology and Biomedical Engineering;Cornelius J. Pings Chair in Biomedical Sciences;Director, USC Ginsburg Institute for Biomedical Therapeutics;Co-Director, USC Roski Eye Institute
Ophthalmology
HC4 6534B 1450 San Pablo Street Health Sciences Campus Los Angeles

USC Roski Eye Institute: Narsing A. Rao, MD Endowed Lecture Award, 2022

Association for Research in Vision and Ophthalmology: ARVO Fellows Class of 2022, 2022

American Association for the Advancement of Science: American Association for the Advancement of Science (AAAS) Fellow, 2022

Super Doctors Southern California Magazine: Southern California Super Doctors, 2021

Retina Research Foundation: Retina Research Foundation Award of Merit (The Schepens Lecture), 2021

USC Stevens Center for Innovation: 2020 Technology Commercialization Award, 2021

American Society of Retina Specialists: Gertrude D. Pyron Award, 2020

European Vitreo Retinal Society: The Relja Zivojnovic Award, 2020

Institute of Electrical and Electronics Engineers: 2020 IEEE Medal for Innovations in Healthcare Technology, 2020

Duke Medical Alumni Association: Distinguished Alumnus Award, 2019

Georgetown University: Doctor of Humane Letters, Honoris Causa, 2019

University of Southern California: USC Stevens Center Commercialization Award, 2019

Farabi Eye Hospital: 2018 Persian Ophthalmologist, 2018

Future Vision Foundation: 2018 Future Vision Award, 2018

Eye and Ear Foundation, University of Pittsburgh: 2018 Muse Prize in Ophthalmology, 2018

Institute of Electrical and Electronics Engineers: IEEE Biomedical Engineering Award, 2018

: National Academy of Inventors Fellows Medallion, 2017

: USC Presidential Medallion, 2017

: National Medal of Technology and Innovation, 2016

Wills Eye Institute: Richard Ellis Award, 2014

Pasadena Magazine: Top Doctors in Ophthalmology, 2013-2014

UIC Illinois Eye and Ear Infirmary: Morton F. Goldberg Endowed Lecturer Medallion, 2013

U.S. World & News Report: Top 1% of Ophthalmologists, 2011

Castle Connolly Medical Ltd. : America's Top Doctors, 2011

: Popular Mechanics Breakthrough Award, 2010

The Retina Society: Award of Merit in Retina Research, 2009

: Best Doctors in Southern California Award, 2009

: Best Doctors of America Award, 2005-2007

: Strathmore's Who's Who Award, 2005-2006

R&D magazine: Innovator of the Year award, 2005

: Senior Honor Award of the Am. Soc. Retina Specialists, 2004

: Jules Stein Living tribute Award, 2002

: William and Mary Grieve Scholar's Award, 1997-1998

: Richard S. Ross Clinical Scientist Award, 1997-1998

ONS-5010 (bevacizumab-vikg) Safety and Efficacy in Subfoveal Choroidal Neovascularization Secondary to Age-related Macular Degeneration Ophthalmic Surg Lasers Imaging Retina. 2024 Nov 01; 1-12. . View in PubMed

Characterization of Induced Current Density During Transcorneal Electrical Stimulation to Promote Neuroprotection in the Degenerating Retina IEEE Trans Biomed Eng. 2024 Nov; 71(11):3221-3231. . View in PubMed

Long-term Follow-up of a Phase 1/2a Clinical Trial of a Stem Cell-Derived Bioengineered Retinal Pigment Epithelium Implant for Geographic Atrophy Ophthalmology. 2024 Jun; 131(6):682-691. . View in PubMed

Noninvasive imaging-guided ultrasonic neurostimulation with arbitrary 2D patterns and its application for high-quality vision restoration Nat Commun. 2024 May 27; 15(1):4481. . View in PubMed

Rescuing Photoreceptors in RPE Dysfunction-Driven Retinal Degeneration: The Role of Small Extracellular Vesicles Secreted from Retinal Pigment Epithelium bioRxiv. 2024 Apr 13. . View in PubMed

Unveiling Drivers of Retinal Degeneration in RCS Rats: Functional, Morphological, and Molecular Insights Int J Mol Sci. 2024 Mar 28; 25(7). . View in PubMed

Scaling up polarized RPE cell supernatant production on parylene membrane Exp Eye Res. 2024 Mar; 240:109789. . View in PubMed

Integrating a Fundus Camera with High-Frequency Ultrasound for Precise Ocular Lesion Assessment Biosensors (Basel). 2024 Feb 29; 14(3). . View in PubMed

Loss of 15-Lipoxygenase in Retinodegenerative RCS Rats Int J Mol Sci. 2024 Feb 15; 25(4). . View in PubMed

Hydroxypropyl-Beta Cyclodextrin Barrier Prevents Respiratory Viral Infections: A Preclinical Study Int J Mol Sci. 2024 Feb 08; 25(4). . View in PubMed

Flow Characterization in a Partially Liquefied Vitreous Humor Transp Porous Media. 2024 Feb; 151(3):533-558. . View in PubMed

Author Correction: An extraocular electrical stimulation approach to slow down the progression of retinal degeneration in an animal model Sci Rep. 2023 Oct 23; 13(1):18120. . View in PubMed

Gaps and future of human-centered artificial intelligence in ophthalmology: Future Vision Forum consensus statement Curr Opin Ophthalmol. 2023 Sep 01; 34(5):431-436. . View in PubMed

Non-Invasive Hybrid Ultrasound Stimulation of Visual Cortex In Vivo Bioengineering (Basel). 2023 May 10; 10(5). . View in PubMed

Ultrasound Concave 2-D Ring Array for Retinal Stimulation IEEE Trans Ultrason Ferroelectr Freq Control. 2023 11; 70(11):1527-1535. . View in PubMed

Simultaneous Assessment of the Whole Eye Biomechanics Using Ultrasonic Elastography IEEE Trans Biomed Eng. 2023 04; 70(4):1310-1317. . View in PubMed

Computational optimization of delivery parameters to guide the development of targeted Nasal spray Sci Rep. 2023 03 12; 13(1):4099. . View in PubMed

Polarized RPE Secretome Preserves Photoreceptors in Retinal Dystrophic RCS Rats Cells. 2023 06 22; 12(13). . View in PubMed

An extraocular electrical stimulation approach to slow down the progression of retinal degeneration in an animal model Sci Rep. 2023 09 23; 13(1):15924. . View in PubMed

Design and Simulation of a Ring Transducer Array for Ultrasound Retinal Stimulation Micromachines (Basel). 2022 Sep 16; 13(9). . View in PubMed

Mathematical Model of Macromolecular Drug Transport in a Partially Liquefied Vitreous Humor J Heat Transfer. 2022 Mar 01; 144(3):031208. . View in PubMed

Ultrasound Retinal Stimulation: A Mini-Review of Recent Developments IEEE Trans Ultrason Ferroelectr Freq Control. 2022 12; 69(12):3224-3231. . View in PubMed

Advanced Retina Implants Ophthalmol Retina. 2022 10; 6(10):899-905. . View in PubMed

Super-Resolution Ultrasound Localization Microscopy for Visualization of the Ocular Blood Flow IEEE Trans Biomed Eng. 2022 05; 69(5):1585-1594. . View in PubMed

Focused ultrasound stimulation on meibomian glands for the treatment of evaporative dry eye Exp Biol Med (Maywood). 2022 03; 247(6):519-526. . View in PubMed

Flexible ultrasound-induced retinal stimulating piezo-arrays for biomimetic visual prostheses Nat Commun. 2022 07 04; 13(1):3853. . View in PubMed

Selective Activation of Retinal Ganglion Cell Subtypes Through Targeted Electrical Stimulation Parameters IEEE Trans Neural Syst Rehabil Eng. 2022; 30:350-359. . View in PubMed

Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration Stem Cell Reports. 2022 03 08; 17(3):448-458. . View in PubMed

Noninvasive Ultrasound Retinal Stimulation for Vision Restoration at High Spatiotemporal Resolution BME Front. 2022; 2022:9829316. . View in PubMed

Development of Moderate Intensity Focused Ultrasound (MIFU) for Ocular Drug Delivery BME Front. 2022; 2022:9840678. . View in PubMed

Development of a Surgical Technique for Subretinal Implants in Rats J Vis Exp. 2022 12 02; (190). . View in PubMed

Analytical and Computational Modeling of Sustained-Release Drug Implants in the Vitreous Humor J Heat Transfer. 2021 Oct 01; 143(10):101201. . View in PubMed

Publisher Correction: Color and cellular selectivity of retinal ganglion cell subtypes through frequency modulation of electrical stimulation Sci Rep. 2021 Jun 14; 11(1):12855. . View in PubMed

Electronic retinal prosthesis for severe loss of vision in geographic atrophy in age-related macular degeneration: First-in-human use Eur J Ophthalmol. 2021 May; 31(3):920-931. . View in PubMed

Tissue Engineering Strategies for Retina Regeneration Appl Sci (Basel). 2021 Mar; 11(5). . View in PubMed

High resolution optical coherence elastography of retina under prosthetic electrode Quant Imaging Med Surg. 2021 Mar; 11(3):918-927. . View in PubMed

In Vivo Experimental and Analytical Studies for Bevacizumab Diffusion Coefficient Measurement in the Rabbit Vitreous Humor J Heat Transfer. 2021 Mar 01; 143(3):032101. . View in PubMed

Novel probabilistic model of core vitreous traction using microsurgical vitrectomy tools Graefes Arch Clin Exp Ophthalmol. 2021 Feb; 259(2):405-412. . View in PubMed

Ultrasonic elastography to assess biomechanical properties of the optic nerve head and peripapillary sclera of the eye Ultrasonics. 2021 Feb; 110:106263. . View in PubMed

NAP1051, a Lipoxin A4 Biomimetic Analogue, Demonstrates Antitumor Activity Against the Tumor Microenvironment Mol Cancer Ther. 2021 12; 20(12):2384-2397. . View in PubMed

Modeling ON Cone Bipolar Cells for Electrical Stimulation Annu Int Conf IEEE Eng Med Biol Soc. 2021 11; 2021:6547-6550. . View in PubMed

On the Design of an Efficient Inductive Wireless Power Transfer for Passive Neurostimulation Systems Annu Int Conf IEEE Eng Med Biol Soc. 2021 11; 2021:7497-7501. . View in PubMed

Restoring Color Perception to the Blind: An Electrical Stimulation Strategy of Retina in Patients with End-stage Retinitis Pigmentosa Ophthalmology. 2021 03; 128(3):453-462. . View in PubMed

Transcranial Focused Ultrasound for Noninvasive Neuromodulation of the Visual Cortex IEEE Trans Ultrason Ferroelectr Freq Control. 2021 01; 68(1):21-28. . View in PubMed

First Human Results With the 256 Channel Intelligent Micro Implant Eye (IMIE 256) Transl Vis Sci Technol. 2021 08 12; 10(10):14. . View in PubMed

Mechanisms underlying activation of retinal bipolar cells through targeted electrical stimulation: a computational study J Neural Eng. 2021 12 15; 18(6). . View in PubMed

Long-Term Transplant Effects of iPSC-RPE Monolayer in Immunodeficient RCS Rats Cells. 2021 10 29; 10(11). . View in PubMed

One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration Transl Vis Sci Technol. 2021 08 12; 10(10):13. . View in PubMed

Layer-specific ultrasound elastography using a multi-layered shear wave dispersion model for assessing the viscoelastic properties Phys Med Biol. 2021 01 26; 66(3):035003. . View in PubMed

Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo Sci Rep. 2021 03 18; 11(1):6286. . View in PubMed

One-Year Anatomical and Functional Outcomes of the Argus II Implantation in Korean Patients with Late-Stage Retinitis Pigmentosa: A Prospective Case Series Study Ophthalmologica. 2021; 244(4):291-300. . View in PubMed

Color and cellular selectivity of retinal ganglion cell subtypes through frequency modulation of electrical stimulation Sci Rep. 2021 03 04; 11(1):5177. . View in PubMed

Blocking Ocular Sympathetic Activity Inhibits Choroidal Neovascularization Front Neurosci. 2021; 15:780841. . View in PubMed

Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats Front Neurosci. 2021; 15:752958. . View in PubMed

Ultrasonic Retinal Neuromodulation and Acoustic Retinal Prosthesis Micromachines (Basel). 2020 Oct 13; 11(10). . View in PubMed

ADVERSE EVENTS OF THE ARGUS II RETINAL PROSTHESIS: Incidence, Causes, and Best Practices for Managing and Preventing Conjunctival Erosion Retina. 2020 Feb; 40(2):303-311. . View in PubMed

Targeted Stimulation of Retinal Ganglion Cells in Epiretinal Prostheses: A Multiscale Computational Study IEEE Trans Neural Syst Rehabil Eng. 2020 11; 28(11):2548-2556. . View in PubMed

In Vivo Visualization of Eye Vasculature Using Super-Resolution Ultrasound Microvessel Imaging IEEE Trans Biomed Eng. 2020 10; 67(10):2870-2880. . View in PubMed

Responsiveness of Retinal Ganglion Cells Through Frequency Modulation of Electrical Stimulation: A Computational Modeling Study Annu Int Conf IEEE Eng Med Biol Soc. 2020 07; 2020:3393-3398. . View in PubMed

Hypotony and the Argus II retinal prosthesis: causes, prevention and management Br J Ophthalmol. 2020 04; 104(4):518-523. . View in PubMed

Surgical Method for Implantation of a Biosynthetic Retinal Pigment Epithelium Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study Ophthalmol Retina. 2020 03; 4(3):264-273. . View in PubMed

In vivo evaluation of posterior eye elasticity using shaker-based optical coherence elastography Exp Biol Med (Maywood). 2020 02; 245(4):282-288. . View in PubMed

Cyanine Nanocage Activated by Near-IR Light for the Targeted Delivery of Cyclosporine A to Traumatic Brain Injury Sites Mol Pharm. 2020 12 07; 17(12):4499-4509. . View in PubMed

Economic Value of Anti-Vascular Endothelial Growth Factor Treatment for Patients With Wet Age-Related Macular Degeneration in the United States JAMA Ophthalmol. 2020 01 01; 138(1):40-47. . View in PubMed

MEASUREMENT OF THE HYDRAULIC CONDUCTIVITY OF THE VITREOUS HUMOR J Porous Media. 2020; 23(2):195-206. . View in PubMed

Retina-electrode interface properties and vision restoration by two generations of retinal prostheses in one patient-one in each eye J Neural Eng. 2020 04 09; 17(2):026020. . View in PubMed

Cyanine Nanocages Activated by Near-Infrared Light for the Targeted Treatment of Traumatic Brain Injury Front Chem. 2020; 8:769. . View in PubMed

Quantitative confocal optical coherence elastography for evaluating biomechanics of optic nerve head using Lamb wave model Neurophotonics. 2019 Oct; 6(4):041112. . View in PubMed

Evaluating New Ophthalmic Digital Devices for Safety and Effectiveness in the Context of Rapid Technological Development JAMA Ophthalmol. 2019 Aug 01; 137(8):939-944. . View in PubMed

Histopathologic Assessment of Optic Nerves and Retina From a Patient With Chronically Implanted Argus II Retinal Prosthesis System Transl Vis Sci Technol. 2019 May; 8(3):31. . View in PubMed

Diffusive Transport in the Vitreous Humor: Experimental and Analytical Studies J Heat Transfer. 2019 May; 141(5):050801. . View in PubMed

A Novel Racing Array Transducer for Noninvasive Ultrasonic Retinal Stimulation: A Simulation Study Sensors (Basel). 2019 Apr 17; 19(8). . View in PubMed

Flexible piezoelectric ultrasonic energy harvester array for bio-implantable wireless generator Nano Energy. 2019 Feb; 56:216-224. . View in PubMed

Ultrasonic Microelastography to Assess Biomechanical Properties of the Cornea IEEE Trans Biomed Eng. 2019 03; 66(3):647-655. . View in PubMed

Thomas ASwift's Electric Rifle Injuries to the Eye and Ocular Adnexa: The Management of Complex Trauma. Ophthalmol Retina. 2019 03; 3(3):258-269. . View in PubMed

Argus II Retinal Prosthesis Implantation in a Patient With a History Of Strabismus Surgery:A Surgical Technique Ophthalmic Surg Lasers Imaging Retina. 2019 02 01; 50(2):116-119. . View in PubMed

Sympathetic Effects of Internal Carotid Nerve Manipulation on Choroidal Vascularity and Related Measures Invest Ophthalmol Vis Sci. 2019 10 01; 60(13):4303-4309. . View in PubMed

Subretinal Implantation of a Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium Monolayer in a Porcine Model Adv Exp Med Biol. 2019; 1185:569-574. . View in PubMed

Enhanced Depth Navigation Through Augmented Reality Depth Mapping in Patients with Low Vision Sci Rep. 2019 08 02; 9(1):11230. . View in PubMed

A new immunodeficient retinal dystrophic rat model for transplantation studies using human-derived cells Graefes Arch Clin Exp Ophthalmol. 2018 Nov; 256(11):2113-2125. . View in PubMed

VISUAL AND ANATOMICAL OUTCOMES AFTER DIABETIC TRACTION AND TRACTION-RHEGMATOGENOUS RETINAL DETACHMENT REPAIR Retina. 2018 Oct; 38(10):1913-1919. . View in PubMed

Quantified elasticity mapping of retinal layers using synchronized acoustic radiation force optical coherence elastography Biomed Opt Express. 2018 Sep 01; 9(9):4054-4063. . View in PubMed

Chronically Implantable Package Based on Alumina Ceramics and Titanium with High-density Feedthroughs for Medical Implants Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:3382-3385. . View in PubMed

Implantation of multiple suprachoroidal electrode arrays in rabbits J Curr Ophthalmol. 2018 Mar; 30(1):68-73. . View in PubMed

Development of a KNN Ceramic-Based Lead-Free Linear Array Ultrasonic Transducer IEEE Trans Ultrason Ferroelectr Freq Control. 2018 11; 65(11):2113-2120. . View in PubMed

Retinal Anatomy and Electrode Array Position in Retinitis Pigmentosa Patients After Argus II Implantation: An International Study Am J Ophthalmol. 2018 09; 193:87-99. . View in PubMed

Increasing Electrical Stimulation Efficacy in Degenerated Retina: Stimulus Waveform Design in a Multiscale Computational Model IEEE Trans Neural Syst Rehabil Eng. 2018 06; 26(6):1111-1120. . View in PubMed

Temporal Neuromodulation of Retinal Ganglion Cells by Low-Frequency Focused Ultrasound Stimulation IEEE Trans Neural Syst Rehabil Eng. 2018 05; 26(5):969-976. . View in PubMed

High-Performance Ultrasound Needle Transducer Based on Modified PMN-PT Ceramic With Ultrahigh Clamped Dielectric Permittivity IEEE Trans Ultrason Ferroelectr Freq Control. 2018 02; 65(2):223-230. . View in PubMed

A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration Sci Transl Med. 2018 04 04; 10(435). . View in PubMed

Disintegrin-Integrin Binding for Attachment of Polymer Substrate to the Retina J Clin Exp Ophthalmol. 2018; 9(5). . View in PubMed

Stereological Method in Optical Coherence Tomography for In Vivo Evaluation of Laser-Induced Choroidal Neovascularization Ophthalmic Surg Lasers Imaging Retina. 2018 09 01; 49(9):e65-e74. . View in PubMed

A reversible thermoresponsive sealant for temporary closure of ocular trauma Sci Transl Med. 2017 Dec 06; 9(419). . View in PubMed

Flexible microelectrode array for retinal prosthesis Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul; 2017:1097-1100. . View in PubMed

High-performance iridium oxide/platinum nano-leaf composite coatings on microelectrodes for neural stimulation/recording Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul; 2017:1070-1073. . View in PubMed

Parylene scaffold for cartilage lesion Biomed Microdevices. 2017 06; 19(2):26. . View in PubMed

Positive Visual Phenomena Following Implantation of the Argus II Retinal Prosthesis Ophthalmic Surg Lasers Imaging Retina. 2017 12 01; 48(12):1022-1025. . View in PubMed

THE SECOND BLIND SPOT: SMALL RETINAL VESSEL VASCULOPATHY AFTER VACCINATION AGAINST NEISSERIA MENINGITIDIS AND YELLOW FEVER Retin Cases Brief Rep. 2017 Winter; 11 Suppl 1:S18-S23. . View in PubMed

Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models Stem Cells Int. 2017; 2017:9428176. . View in PubMed

Development of a new tissue injector for subretinal transplantation of human embryonic stem cell derived retinal pigmented epithelium Int J Retina Vitreous. 2017; 3:41. . View in PubMed

The Bionic Eye: A Quarter Century of Retinal Prosthesis Research and Development Ophthalmology. 2016 Oct; 123(10S):S89-S97. . View in PubMed

Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs Graefes Arch Clin Exp Ophthalmol. 2016 Aug; 254(8):1553-1565. . View in PubMed

Strategies to improve stimulation efficiency for retinal prostheses Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug; 2016:3133-3138. . View in PubMed

INTRAOCULAR PRESSURE CHANGES DURING VITRECTOMY USING CONSTELLATION VISION SYSTEM'S INTRAOCULAR PRESSURE CONTROL FEATURE Retina. 2016 Jul; 36(7):1275-80. . View in PubMed

NorLeu3A(1-7) Accelerates Clear Corneal Full Thickness Wound Healing Invest Ophthalmol Vis Sci. 2016 Apr 01; 57(4):2187-94. . View in PubMed

An Innovative Surgical Technique for Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium in Yucatan Mini Pigs: Preliminary Results Ophthalmic Surg Lasers Imaging Retina. 2016 Apr 01; 47(4):342-51. . View in PubMed

Five-Year Safety and Performance Results from the Argus II Retinal Prosthesis System Clinical Trial Ophthalmology. 2016 10; 123(10):2248-54. . View in PubMed

Retinal stimulation strategies to restore vision: Fundamentals and systems Prog Retin Eye Res. 2016 07; 53:21-47. . View in PubMed

Biomimetic Accommodating Intraocular Lens Using a Valved Deformable Liquid Balloon IEEE Trans Biomed Eng. 2016 06; 63(6):1129-35. . View in PubMed

Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats Invest Ophthalmol Vis Sci. 2016 05 01; 57(6):2877-87. . View in PubMed

Electrical Stimulation of the Retina to Produce Artificial Vision Annu Rev Vis Sci. 2016 10 14; 2:273-294. . View in PubMed

OPTOMAP WIDEFIELD IMAGING OF THE ARGUS II RETINAL PROSTHESIS IN PATIENTS WITH RETINITIS PIGMENTOSA Retin Cases Brief Rep. 2016; 10(4):382-5. . View in PubMed

Spatial Variations in Vitreous Oxygen Consumption PLoS One. 2016; 11(3):e0149961. . View in PubMed

Improving the spatial resolution of epiretinal implants by increasing stimulus pulse duration Sci Transl Med. 2015 Dec 16; 7(318):318ra203. . View in PubMed

Ten-Year Follow-up of a Blind Patient Chronically Implanted with Epiretinal Prosthesis Argus IOphthalmology. 2015 Dec; 122(12):2545-52. e1. . View in PubMed

Stem cell based therapies for age-related macular degeneration: The promises and the challenges Prog Retin Eye Res. 2015 Sep; 48:1-39. . View in PubMed

Monte Carlo analysis of the enhanced transcranial penetration using distributed near-infrared emitter array J Biomed Opt. 2015 Aug; 20(8):88001. . View in PubMed

Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind Ophthalmology. 2015 Aug; 122(8):1547-54. . View in PubMed

Whole vitreous humor dissection for vitreodynamic analysis J Vis Exp. 2015 May 24; (99):e52759. . View in PubMed

Fluidics comparison between dual pneumatic and spring return high-speed vitrectomy systems Ophthalmic Surg Lasers Imaging Retina. 2015 Jan; 46(1):68-72. . View in PubMed

Implantable MicroPump for Drug Delivery in Patients with Diabetic Macular Edema Transl Vis Sci Technol. 2014 Oct; 3(6):5. . View in PubMed

Noninvasive assessment of retinal vascular oxygen content among normal and diabetic human subjects: a study using hyperspectral computed tomographic imaging spectroscopy Retina. 2014 Sep; 34(9):1854-60. . View in PubMed

Elastic properties of human posterior eye J Biomed Mater Res A. 2014 Jun; 102(6):2001-7. . View in PubMed

Retinal prosthesis IEEE Trans Biomed Eng. 2014 May; 61(5):1412-24. . View in PubMed

One-Year Feasibility Study of Replenish MicroPump for Intravitreal Drug Delivery: A Pilot Study Transl Vis Sci Technol. 2014 May; 3(4):8. . View in PubMed

Interphase gap as a means to reduce electrical stimulation thresholds for epiretinal prostheses J Neural Eng. 2014 Feb; 11(1):016007. . View in PubMed

Comparison of reaction response time between hand and foot controlled devices in simulated microsurgical testing Biomed Res Int. 2014; 2014:769296. . View in PubMed

Microdevice-based cell therapy for age-related macular degeneration Dev Ophthalmol. 2014; 53:155-66. . View in PubMed

Profile of ocriplasmin and its potential in the treatment of vitreomacular adhesion Clin Ophthalmol. 2014; 8:847-56. . View in PubMed

A fully intraocular high-density self-calibrating epiretinal prosthesis IEEE Trans Biomed Circuits Syst. 2013 Dec; 7(6):747-60. . View in PubMed

Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer Invest Ophthalmol Vis Sci. 2013 Jul 26; 54(7):5087-96. . View in PubMed

In vivo detection of hESC-RPE cells via confocal near-infrared fundus reflectance Ophthalmic Surg Lasers Imaging Retina. 2013 Jul-Aug; 44(4):380-4. . View in PubMed

A system verification platform for high-density epiretinal prostheses IEEE Trans Biomed Circuits Syst. 2013 Jun; 7(3):326-37. . View in PubMed

Performance analysis of ultrahigh-speed vitreous cutter system Retina. 2013 May; 33(5):928-32. . View in PubMed

The Argus II epiretinal prosthesis system allows letter and word reading and long-term function in patients with profound vision loss Br J Ophthalmol. 2013 May; 97(5):632-6. . View in PubMed

Analysis of a 23-gauge ultra high-speed cutter with duty cycle control Retina. 2013 May; 33(5):933-8. . View in PubMed

Light-triggered modulation of cellular electrical activity by ruthenium diimine nanoswitches ACS Chem Neurosci. 2013 Apr 17; 4(4):585-93. . View in PubMed

Performance of visually guided tasks using simulated prosthetic vision and saliency-based cues J Neural Eng. 2013 Apr; 10(2):026017. . View in PubMed

Imaging the response of the retina to electrical stimulation with genetically encoded calcium indicators J Neurophysiol. 2013 Apr; 109(7):1979-88. . View in PubMed

Factors Affecting Perceptual Threshold in Argus II Retinal Prosthesis Subjects Transl Vis Sci Technol. 2013 Apr; 2(4):1. . View in PubMed

Quantitative analysis of retinal structures using spectral domain optical coherence tomography in normal rabbits Curr Eye Res. 2013 Feb; 38(2):299-304. . View in PubMed

Fluidics in a dual pneumatic ultra high-speed vitreous cutter system Ophthalmologica. 2013; 229(1):15-20. . View in PubMed

In vivo Sonothrombolysis of Ear Marginal Vein of Rabbits Monitored with High-frequency Ultrasound Needle Transducer J Med Biol Eng. 2013; 33(1):103-110. . View in PubMed

High-resolution OCT: an innovative tool for posterior segment imaging Ophthalmic Surg Lasers Imaging. 2012 Nov-Dec; 43(6 Suppl):S123-34. . View in PubMed

Evaluation of ultrasound-assisted thrombolysis using custom liposomes in a model of retinal vein occlusion Invest Ophthalmol Vis Sci. 2012 Oct 05; 53(11):6920-7. . View in PubMed

Fluorescein angiography, optical coherence tomography, and histopathologic findings in a VEGF(165) animal model of retinal angiogenesis Graefes Arch Clin Exp Ophthalmol. 2012 Oct; 250(10):1421-8. . View in PubMed

Mesh-supported submicron parylene-C membranes for culturing retinal pigment epithelial cells Biomed Microdevices. 2012 Aug; 14(4):659-67. . View in PubMed

Artificial vision through neuronal stimulation Neurosci Lett. 2012 Jun 25; 519(2):122-8. . View in PubMed

Preservation of retinotopic map in retinal degeneration Exp Eye Res. 2012 May; 98:88-96. . View in PubMed

Response to 'technology for mobility in SCI ten years from now' Spinal Cord. 2012 May; 50(5):364. . View in PubMed

Assessment of MRI issues for the Argus II retinal prosthesis Magn Reson Imaging. 2012 Apr; 30(3):382-9. . View in PubMed

Interim results from the international trial of Second Sight's visual prosthesis Ophthalmology. 2012 Apr; 119(4):779-88. . View in PubMed

Frequency and amplitude modulation have different effects on the percepts elicited by retinal stimulation Invest Ophthalmol Vis Sci. 2012 Jan 20; 53(1):205-14. . View in PubMed

A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer Ophthalmic Res. 2012; 48(4):186-91. . View in PubMed

Acute variations in retinal vascular oxygen content in a rabbit model of retinal venous occlusion PLoS One. 2012; 7(11):e50179. . View in PubMed

Impedance as a method to sense proximity at the electrode-retina interface IEEE Trans Neural Syst Rehabil Eng. 2011 Dec; 19(6):696-9. . View in PubMed

Retinal prostheses: current clinical results and future needs Ophthalmology. 2011 Nov; 118(11):2227-37. . View in PubMed

Resolution of the epiretinal prosthesis is not limited by electrode size IEEE Trans Neural Syst Rehabil Eng. 2011 Aug; 19(4):436-42. . View in PubMed

Continuous electrical stimulation decreases retinal excitability but does not alter retinal morphology J Neural Eng. 2011 Aug; 8(4):045003. . View in PubMed

Modeling and percept of transcorneal electrical stimulation in humans IEEE Trans Biomed Eng. 2011 Jul; 58(7):1932-9. . View in PubMed

Morphometric analysis of optic nerves and retina from an end-stage retinitis pigmentosa patient with an implanted active epiretinal array Invest Ophthalmol Vis Sci. 2011 Jun 28; 52(7):4610-6. . View in PubMed

Both electrical stimulation thresholds and SMI-32-immunoreactive retinal ganglion cell density correlate with age in S334ter line 3 rat retina J Neurophysiol. 2011 Jun; 105(6):2687-97. . View in PubMed

Blind subjects implanted with the Argus II retinal prosthesis are able to improve performance in a spatial-motor task Br J Ophthalmol. 2011 Apr; 95(4):539-43. . View in PubMed

Performance analysis of millennium vitreous enhancer™ system Ophthalmic Surg Lasers Imaging. 2011 Mar-Apr; 42(2):162-7. . View in PubMed

Vitreal oxygenation in retinal ischemia reperfusion Invest Ophthalmol Vis Sci. 2011 Feb; 52(2):1035-42. . View in PubMed

Interphase gap decreases electrical stimulation threshold of retinal ganglion cells Annu Int Conf IEEE Eng Med Biol Soc. 2011; 2011:6725-8. . View in PubMed

Hyperspectral computed tomographic imaging spectroscopy of vascular oxygen gradients in the rabbit retina in vivo PLoS One. 2011; 6(9):e24482. . View in PubMed

A new dual port cutter system for vitrectomy surgery Retina. 2010 Oct; 30(9):1515-9. . View in PubMed

Novel method to quantify traction in a vitrectomy procedure Br J Ophthalmol. 2010 Sep; 94(9):1226-9. . View in PubMed

An experimental protocol of the model to quantify traction applied to the retina by vitreous cutters Invest Ophthalmol Vis Sci. 2010 Aug; 51(8):4181-6. . View in PubMed

Vitreoretinal traction created by conventional cutters during vitrectomyOphthalmology. 2010 Jul; 117(7):1387-92. e2. . View in PubMed

Ultrasonic Doppler measurements of blood flow velocity of rabbit retinal vessels using a 45-MHz needle transducer Graefes Arch Clin Exp Ophthalmol. 2010 May; 248(5):675-80. . View in PubMed

Effect of multiple injections of small divided doses vs single injection of intravitreal bevacizumab on retinal neovascular model in rabbits Graefes Arch Clin Exp Ophthalmol. 2010 Apr; 248(4):457-66. . View in PubMed

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Determining the acoustic properties of the lens using a high-frequency ultrasonic needle transducer Ultrasound Med Biol. 2007 Dec; 33(12):1971-7. . View in PubMed

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A novel method to oxygenate intraocular irrigation fluids with an in-line oxygenator Retina. 2007 Jan; 27(1):83-6. . View in PubMed

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Intraocular retinal prosthesisBig steps to sight restoration. IEEE Eng Med Biol Mag. 2006 Sep-Oct; 25(5):60-6. . View in PubMed

Enucleated eye model for intraocular retinal prosthesis implantation Ophthalmic Surg Lasers Imaging. 2006 Jul-Aug; 37(4):341-3. . View in PubMed

Nanobiolistic delivery of indicators to the living mouse retina J Neurosci Methods. 2006 May 15; 153(1):154-61. . View in PubMed

In vitro and in vivo evaluation of ultrananocrystalline diamond for coating of implantable retinal microchips J Biomed Mater Res B Appl Biomater. 2006 May; 77(2):273-81. . View in PubMed

Retinal prostheses for the blind Ann Acad Med Singap. 2006 Mar; 35(3):137-44. . View in PubMed

Paragraph text reading using a pixelized prosthetic vision simulator: parameter dependence and task learning in free-viewing conditions Invest Ophthalmol Vis Sci. 2006 Mar; 47(3):1241-50. . View in PubMed

One-year results of a pilot study using oral 13-cis retinoic acid as a treatment for subfoveal predominantly occult choroidal neovascularization in patients with age-related macular degeneration Retina. 2006 Mar; 26(3):314-21. . View in PubMed

A dual band wireless power and data telemetry for retinal prosthesis Conf Proc IEEE Eng Med Biol Soc. 2006; 2006:4392-5. . View in PubMed

Implantation of an inactive epiretinal poly(dimethyl siloxane) electrode array in dogs Exp Eye Res. 2006 Jan; 82(1):81-90. . View in PubMed

Neural responses elicited by electrical stimulation of the retina Trans Am Ophthalmol Soc. 2006; 104:252-9. . View in PubMed

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A biomimetic retinal stimulating array IEEE Eng Med Biol Mag. 2005 Sep-Oct; 24(5):14-21. . View in PubMed

Rapid recurrence of geographic atrophy after full macular translocation for nonexudative age-related macular degeneration Ophthalmology. 2005 Sep; 112(9):1586-91. . View in PubMed

Improvement after transvitreal limited arteriovenous crossing manipulation without vitrectomy for complicated branch retinal vein occlusion using 25 gauge instrumentation Br J Ophthalmol. 2005 Jul; 89(7):922-3. . View in PubMed

Perceptual thresholds and electrode impedance in three retinal prosthesis subjects IEEE Trans Neural Syst Rehabil Eng. 2005 Jun; 13(2):201-6. . View in PubMed

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Transvitreal limited arteriovenous-crossing manipulation without vitrectomy for complicated branch retinal vein occlusion using 25-gauge instrumentation Retina. 2005 Apr-May; 25(3):272-80. . View in PubMed

Long-term stimulation by active epiretinal implants in normal and RCD1 dogs J Neural Eng. 2005 Mar; 2(1):S65-73. . View in PubMed

Laser-induced changes in intraretinal oxygen distribution in pigmented rabbits Invest Ophthalmol Vis Sci. 2005 Mar; 46(3):988-99. . View in PubMed

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Integrated flexible ocular coil for power and data transfer in retinal prostheses Conf Proc IEEE Eng Med Biol Soc. 2005; 2006:1028-31. . View in PubMed

A wireless phase shift keying transmitter with q-independent phase transition time Conf Proc IEEE Eng Med Biol Soc. 2005; 2005:5238-41. . View in PubMed

A programmable discharge circuitry with current limiting capability for a retinal prosthesis Conf Proc IEEE Eng Med Biol Soc. 2005; 2005:5234-7. . View in PubMed

Progress towards a high-resolution retinal prosthesis Conf Proc IEEE Eng Med Biol Soc. 2005; 2005:7373-5. . View in PubMed

Retinal vein cannulation with prolonged infusion of tissue plasminogen activator (t-PA) for the treatment of experimental retinal vein occlusion in dogs Am J Ophthalmol. 2004 Nov; 138(5):829-39. . View in PubMed

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Macular translocation in patients with recurrent subfoveal choroidal neovascularization after laser photocoagulation for nonsubfoveal choroidal neovascularization Ophthalmology. 2004 Oct; 111(10):1889-93. . View in PubMed

Electrical stimulation of isolated retina with microwire glass electrodes J Neurosci Methods. 2004 Aug 30; 137(2):265-73. . View in PubMed

Thermal elevation in the human eye and head due to the operation of a retinal prosthesis IEEE Trans Biomed Eng. 2004 Aug; 51(8):1469-77. . View in PubMed

Comparison of electrical stimulation thresholds in normal and retinal degenerated mouse retina Jpn J Ophthalmol. 2004 Jul-Aug; 48(4):345-9. . View in PubMed

Use of rotational sutures for limited retinal translocation: a new technique for superior limited macular translocation Am J Ophthalmol. 2004 May; 137(5):901-7. . View in PubMed

Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor: implications for ocular angiogenesis Am J Ophthalmol. 2004 Apr; 137(4):668-74. . View in PubMed

Virtual vitreoretinal surgical simulator as a training tool Retina. 2004 Apr; 24(2):231-6. . View in PubMed

Effects of intravitreal indocyanine green injection in rabbits Retina. 2004 Feb; 24(1):69-79. . View in PubMed

Retinal pigment epithelial abnormalities after internal limiting membrane peeling guided by indocyanine green staining Retina. 2004 Feb; 24(1):157-60. . View in PubMed

Effects of indocyanine green injection on the retinal surface and into the subretinal space in rabbits Retina. 2004 Feb; 24(1):80-91. . View in PubMed

Intraocular impedance as a function of the position in the eye, electrode material and electrode size Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:4169-71. . View in PubMed

Visual task performance in blind humans with retinal prosthetic implants Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:4172-3. . View in PubMed

DSP based image processing for retinal prosthesis Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:1475-8. . View in PubMed

A test microchip for evaluation of hermetic packaging technology for biomedical prosthetic implants Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:4093-5. . View in PubMed

Characteristics of visual loss by scanning laser ophthalmoscope microperimetry in eyes with subfoveal choroidal neovascularization secondary to age-related macular degeneration Am J Ophthalmol. 2003 Dec; 136(6):1067-78. . View in PubMed

Visual perception in a blind subject with a chronic microelectronic retinal prosthesis Vision Res. 2003 Nov; 43(24):2573-81. . View in PubMed

Past, present, and future of artificial vision Artif Organs. 2003 Nov; 27(11):961-2. . View in PubMed

Facial recognition using simulated prosthetic pixelized vision Invest Ophthalmol Vis Sci. 2003 Nov; 44(11):5035-42. . View in PubMed

Visually guided performance of simple tasks using simulated prosthetic vision Artif Organs. 2003 Nov; 27(11):1016-28. . View in PubMed

Bilateral neuroretinopathy with multiple retinal arterial aneurysms Arch Ophthalmol. 2003 Aug; 121(8):1206-7. . View in PubMed

Advances in the development of visual prostheses Curr Opin Ophthalmol. 2003 Jun; 14(3):122-7. . View in PubMed

Angiographic characteristics in patients undergoing macular translocation for subfoveal choroidal neovascularization secondary to age-related macular degeneration Retina. 2003 Apr; 23(2):152-8. . View in PubMed

Visual and electrical evoked response recorded from subdural electrodes implanted above the visual cortex in normal dogs under two methods of anesthesia J Neurosci Methods. 2003 Mar 15; 123(2):129-37. . View in PubMed

Heat effects on the retina Ophthalmic Surg Lasers Imaging. 2003 Mar-Apr; 34(2):114-20. . View in PubMed

The value of preoperative tests in the selection of blind patients for a permanent microelectronic implant Trans Am Ophthalmol Soc. 2003; 101:223-8; discussion 228-30. . View in PubMed

Limited macular translocation for the management of subfoveal choroidal neovascularization after photodynamic therapy Am J Ophthalmol. 2003 Jan; 135(1):109-12. . View in PubMed

Improvements after sheathotomy for branch retinal vein occlusion documented by optical coherence tomography and scanning laser ophthalmoscope Ophthalmic Surg Lasers Imaging. 2003 Jan-Feb; 34(1):49-52. . View in PubMed

Limited macular translocation: current concepts Ophthalmol Clin North Am. 2002 Dec; 15(4):425-36. . View in PubMed

In vitro electrical properties for iridium oxide versus titanium nitride stimulating electrodes IEEE Trans Biomed Eng. 2002 Dec; 49(12 Pt 2):1574-9. . View in PubMed

A new 25-gauge instrument system for transconjunctival sutureless vitrectomy surgery Ophthalmology. 2002 Oct; 109(10):1807-12; discussion 1813. . View in PubMed

Initial experience using the transconjunctival sutureless vitrectomy system for vitreoretinal surgery Ophthalmology. 2002 Oct; 109(10):1814-20. . View in PubMed

Patient selection for macular translocation surgery using the scanning laser ophthalmoscope Ophthalmology. 2002 Sep; 109(9):1737-44. . View in PubMed

Increased spontaneous retinal ganglion cell activity in rd mice after neural retinal transplantation Invest Ophthalmol Vis Sci. 2002 Sep; 43(9):3053-8. . View in PubMed

Morphometric analysis of the macula in eyes with geographic atrophy due to age-related macular degeneration Retina. 2002 Aug; 22(4):464-70. . View in PubMed

Morphometric analysis of the macula in eyes with disciform age-related macular degeneration Retina. 2002 Aug; 22(4):471-7. . View in PubMed

Inferior limited macular translocation for subfoveal choroidal neovascularization secondary to age-related macular degeneration: 1-year visual outcome and recurrence report Am J Ophthalmol. 2002 Jul; 134(1):69-74. . View in PubMed

Retinal prosthesis for the blind Surv Ophthalmol. 2002 Jul-Aug; 47(4):335-56. . View in PubMed

Ganglion cell responses to retinal light stimulation in the absence of photoreceptor outer segments from retinal degenerate rodents Curr Eye Res. 2002 Jan; 24(1):26-32. . View in PubMed

Transient formed visual hallucinations following macular translocation for subfoveal choroidal neovascularization secondary to age-related macular degeneration Am J Ophthalmol. 2001 May; 131(5):664-6. . View in PubMed

Light-driven retinal ganglion cell responses in blind rd mice after neural retinal transplantation Invest Ophthalmol Vis Sci. 2001 Apr; 42(5):1057-65. . View in PubMed

Limited macular translocation for the management of subfoveal retinal pigment epithelial loss after submacular surgery Am J Ophthalmol. 2001 Feb; 131(2):272-5. . View in PubMed

Elevated vitreous concentration of monoclonal immunoglobulin manifesting as schlieren in juvenile rheumatoid arthritis-associated uveitis Arch Ophthalmol. 2001 Feb; 119(2):293-6. . View in PubMed

Macular translocation: unifying concepts, terminology, and classification Am J Ophthalmol. 2001 Feb; 131(2):244-53. . View in PubMed

Intraocular retinal prosthesis Trans Am Ophthalmol Soc. 2001; 99:271-300. . View in PubMed

Retinal prosthesis: an encouraging first decade with major challenges ahead Ophthalmology. 2001 Jan; 108(1):13-4. . View in PubMed

Initial experience of inferior limited macular translocation for subfoveal choroidal neovascularization resulting from causes other than age-related macular degeneration Am J Ophthalmol. 2001 Jan; 131(1):90-100. . View in PubMed

Unintentional transplantation of autologous retinal pigment epithelium during limited macular translocation Retina. 2001; 21(4):380-2. . View in PubMed

Complications associated with limited macular translocation Am J Ophthalmol. 2000 Dec; 130(6):751-62. . View in PubMed

Limited inferior macular translocation for the treatment of subfoveal choroidal neovascularization secondary to age-related macular degeneration Am J Ophthalmol. 2000 Oct; 130(4):419-28. . View in PubMed

Human neural retinal transplantation Invest Ophthalmol Vis Sci. 2000 Sep; 41(10):3100-6. . View in PubMed

Bilateral retinoschisis, retinal neovascularization, and severe myopia in a young female Ophthalmic Surg Lasers. 2000 Sep-Oct; 31(5):442-3. . View in PubMed

Histologic correlation of human neural retinal transplantation Invest Ophthalmol Vis Sci. 2000 Sep; 41(10):3142-8. . View in PubMed

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Perfluoroperhydrophenanthrene versus perfluoro-n-octane in vitreoretinal surgery Ophthalmology. 2000 Jun; 107(6):1078-82. . View in PubMed

The surgical management of hypotony Ophthalmology. 2000 Feb; 107(2):318-23. . View in PubMed

Bioadhesives for intraocular use Retina. 2000; 20(5):469-77. . View in PubMed

Understanding the origin of visual percepts elicited by electrical stimulation of the human retina Graefes Arch Clin Exp Ophthalmol. 1999 Dec; 237(12):1007-13. . View in PubMed

Long-term histological and electrophysiological results of an inactive epiretinal electrode array implantation in dogs Invest Ophthalmol Vis Sci. 1999 Aug; 40(9):2073-81. . View in PubMed

Pattern electrical stimulation of the human retina Vision Res. 1999 Jul; 39(15):2569-76. . View in PubMed

A computational model of electrical stimulation of the retinal ganglion cell IEEE Trans Biomed Eng. 1999 May; 46(5):505-14. . View in PubMed

Allogenic fetal retinal pigment epithelial cell transplant in a patient with geographic atrophy Retina. 1999; 19(6):540-5. . View in PubMed

Morphometric analysis of the extramacular retina from postmortem eyes with retinitis pigmentosa Invest Ophthalmol Vis Sci. 1999 Jan; 40(1):143-8. . View in PubMed

What is the origin of the blood flow? Arch Ophthalmol. 1998 Dec; 116(12):1694-5.. View in PubMed

Management of submacular hemorrhage associated with retinal arterial macroaneurysms Am J Ophthalmol. 1998 Sep; 126(3):358-61. . View in PubMed

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White dot fovea in an African American patient Arch Ophthalmol. 1998 Jan; 116(1):110-1. . View in PubMed

Leukocoria caused by occult penetrating trauma in a child Am J Ophthalmol. 1997 Jul; 124(1):117-9. . View in PubMed

Preservation of the inner retina in retinitis pigmentosaA morphometric analysis. Arch Ophthalmol. 1997 Apr; 115(4):511-5. . View in PubMed

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Mark S. Humayun, MD, PhD, received his Bachelors of Science degree from Georgetown University in 1984, his Doctor of Medicine (MD) from Duke University in 1989, and his PhD from the University of North Carolina, Chapel Hill in 1994. He completed his ophthalmology residency at Duke Eye Center and fellowships in both vitreoretinal and retinovascular surgery at Johns Hopkins Hospital. He stayed on as faculty at Johns Hopkins where he rose to the rank of associate professor before moving to USC in 2001.

Dr. Humayun has devoted much of his career to clinical and scientific research in ophthalmology and bioengineering, becoming both a biomedical engineer and professor of ophthalmology. Dr. Humayun led a talented and diverse team of interdisciplinary researchers with the ultimate goal of creating the world’s first artificial retina. He assembled a team of world experts with a wide range of proficiency, including biomedical engineering, computer science, medicine, chemistry, biology and business. In clinical trials since 2007 and approved by the FDA in 2013, the Argus II retinal implant, represents the culmination of a visual restoration strategy that offers an unprecedented degree of sight to those with complete retinal blindness. He was elected to the prestigious National Academy of Medicine (NAM) and National Academy of Engineering (NAE) for his pioneering work to restore sight.

With over 300 publications and more than 140 patents and patent applications, Dr. Humayun has received several research awards which includes the 2005 Innovator of the Year award. He was also featured as one of the top 10 inventors in Time Magazine in 2013, voted as one of the Best Doctors in America for three years, and one of the top 1% of Doctors by U.S. News & World Report.

In 2016, Dr. Humayun received the National Medal of Technology and Innovation from President Barack Obama for his innovative work and development of the Argus II.
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