Our Team

Faculty

Darrin Jason Lee

Darrin Jason Lee

Associate Professor of Neurological Surgery (Clinical Scholar)
Neurosurgery
1333 San Pablo St. Health Sciences Campus Los Angeles

Brian and Behavior Research Foundation : Brain and Behavior Research Foundation Young Investigator, 2022

American Geriatrics Society: Clinician Specialists Rising Star, 2021

American Academy of Neurological Surgeons: Emerging Investigator Scholar, 2019-2020

American Association of Neurological Surgeons: William P. Van Wagenen Fellow, 2017-2018

Howard Hughes Medical Institute: Howard Hughes Medical Institute Fellow, 2007-2008

Neuromodulation of Eating Disorders: A Review of Underlying Neural Network Activity and Neuromodulatory Treatments Brain Sci. 2024 Feb 22; 14(3). . View in PubMed

Immediate and long-term electrophysiological biomarkers of antidepressant-like behavioral effects after subanesthetic ketamine and medial prefrontal cortex deep brain stimulation treatment Front Neurosci. 2024; 18:1389096. . View in PubMed

Theta-frequency medial septal nucleus deep brain stimulation increases neurovascular activity in MK-801-treated mice Front Neurosci. 2024; 18:1372315. . View in PubMed

Sex differences in regional gray matter density in pre-adolescent binge eating disorder: a voxel-based morphometry study Psychol Med. 2023 10; 53(13):6077-6089. . View in PubMed

Aberrant functional connectivity between reward and inhibitory control networks in pre-adolescent binge eating disorder Psychol Med. 2023 07; 53(9):3869-3878. . View in PubMed

Deep Brain Stimulation beyond the Clinic: Navigating the Future of Parkinson's and Alzheimer's Disease Therapy Cells. 2023 05 25; 12(11). . View in PubMed

Developing Predictive Models to Anticipate Shunt Complications in 33,248 Pediatric Patients with Shunted Hydrocephalus Utilizing Machine Learning Pediatr Neurosurg. 2023; 58(4):206-214. . View in PubMed

A Review of Medical and Surgical Options for the Treatment of Facial Pain Otolaryngol Clin North Am. 2022 Jun; 55(3):607-632. . View in PubMed

Early life social instability stress causes lasting cognitive decrement and elevated hippocampal stress-related gene expression Exp Neurol. 2022 08; 354:114099. . View in PubMed

Frequency-specific medial septal nucleus deep brain stimulation improves spatial memory in MK-801-treated male rats Neurobiol Dis. 2022 08; 170:105756. . View in PubMed

Preexisting Ventricular Shunts Are Associated with Failed Evacuation of Acute Subdural Hematomas: Single-Institution Case Series of Complications and Management Strategies World Neurosurg. 2022 02; 158:e1011-e1016. . View in PubMed

Pathophysiological Mechanisms Underlying Idiopathic Normal Pressure Hydrocephalus: A Review of Recent Insights Front Aging Neurosci. 2022; 14:866313. . View in PubMed

Subthreshold repetitive transcranial magnetic stimulation suppresses ketamine-induced poly population spikes in rat sensorimotor cortex Front Neurosci. 2022; 16:998704. . View in PubMed

Neuromodulation of OCD: A review of invasive and non-invasive methods Front Neurol. 2022; 13:909264. . View in PubMed

Acute low frequency dorsal subthalamic nucleus stimulation improves verbal fluency in Parkinson's disease Brain Stimul. 2021 Jul-Aug; 14(4):754-760. . View in PubMed

Cognitive effects of theta frequency bilateral subthalamic nucleus stimulation in Parkinson's disease: A pilot study Brain Stimul. 2021 Mar-Apr; 14(2):230-240. . View in PubMed

Deep Brain Stimulation for Alzheimer's Disease: Tackling Circuit Dysfunction Neuromodulation. 2021 Feb; 24(2):171-186. . View in PubMed

Transcranial magnetic stimulation & the conundrum of concurrent patient activity: Does symptom provocation matter? Psychiatry Res. 2021 11; 305:114249.. View in PubMed

Gray Matter Atrophy: The Impacts of Resective Surgery and Vagus Nerve Stimulation in Drug-Resistant Epilepsy World Neurosurg. 2021 05; 149:e535-e545. . View in PubMed

Cognitive outcomes following vagus nerve stimulation, responsive neurostimulation and deep brain stimulation for epilepsy: A systematic review Epilepsy Res. 2021 05; 172:106591. . View in PubMed

Commentary: Application of Augmented Reality in Percutaneous Procedures-Rhizotomy of the Gasserian Ganglion Oper Neurosurg (Hagerstown). 2021 08 16; 21(3):E224-E225. . View in PubMed

Gamified Dual-Task Training for Individuals with Parkinson Disease: An Exploratory Study on Feasibility, Safety, and Efficacy Int J Environ Res Public Health. 2021 11 25; 18(23). . View in PubMed

In Reply to the Letter to the Editor Regarding "Subdural Catheter Injection of Tissue Plasminogen Activator for Residual Hematoma Post Drainage of Acute-on-Chronic Subdural Hematoma: Novel Case Report of 2 Patients" World Neurosurg. 2020 02; 134:681. . View in PubMed

Subdural Catheter Injection of Tissue Plasminogen Activator for Residual Hematoma Post Drainage of Acute-on-Chronic Subdural Hematoma: Novel Case Report of 2 Patients World Neurosurg. 2020 Jan; 133:266-270. . View in PubMed

Medial septal stimulation increases seizure threshold and improves cognition in epileptic rats Brain Stimul. 2019 May - Jun; 12(3):735-742. . View in PubMed

Inferior thalamic peduncle deep brain stimulation for treatment-refractory obsessive-compulsive disorder: A phase 1 pilot trial Brain Stimul. 2019 Mar - Apr; 12(2):344-352. . View in PubMed

Successful pallidotomy for post-hyperglycemic hemichorea-ballism Parkinsonism Relat Disord. 2019 04; 61:228-230. . View in PubMed

Outcomes from stereotactic surgery for essential tremor J Neurol Neurosurg Psychiatry. 2019 04; 90(4):474-482. . View in PubMed

Corrigendum to 'Reoperation for Symptomatic Nonunions in Atlantoaxial (C1-C2) Fusions with and without Bone Morphogenetic Protein: A Cohort of 108 Patients with >2 Years Follow-Up' [World Neurosurgery 121 (2019) e458-e466] World Neurosurg. 2019 03; 123:476. . View in PubMed

Deep brain stimulation for pantothenate kinase-associated neurodegeneration: A meta-analysis Mov Disord. 2019 02; 34(2):264-273. . View in PubMed

Deep brain stimulation: potential for neuroprotection Ann Clin Transl Neurol. 2019 01; 6(1):174-185. . View in PubMed

Ultra-high-frequency deep brain stimulation at 10,000 Hz improves motor function Mov Disord. 2019 01; 34(1):146-148. . View in PubMed

Nucleus basalis of Meynert neuronal activity in Parkinson's disease J Neurosurg. 2019 02 22; 132(2):574-582. . View in PubMed

Reoperation for Symptomatic Nonunions in Atlantoaxial (C1-C2) Fusions with and without Bone Morphogenetic Protein: A Cohort of 108 Patients with >2 Years Follow-Up World Neurosurg. 2019 Jan; 121:e458-e466. . View in PubMed

Current and future directions of deep brain stimulation for neurological and psychiatric disorders J Neurosurg. 2019 08 01; 131(2):333-342. . View in PubMed

Long-term results after deep brain stimulation of nucleus accumbens and the anterior limb of the internal capsule for preventing heroin relapse: An open-label pilot study Brain Stimul. 2019 Jan - Feb; 12(1):175-183. . View in PubMed

Long-term relief of intractable hiccups with vagal nerve stimulation Brain Stimul. 2018 Nov - Dec; 11(6):1385-1387. . View in PubMed

Current surgical treatments for Parkinson's disease and potential therapeutic targets Neural Regen Res. 2018 Aug; 13(8):1342-1345. . View in PubMed

Neuromodulation for the treatment of eating disorders and obesity Ther Adv Psychopharmacol. 2018 Feb; 8(2):73-92. . View in PubMed

Cervical spine fractures in osteopetrosis: a case report and review of the literature J Biomed Res. 2018 Jan 18; 32(1):68-76. . View in PubMed

Pallidal deep brain stimulation modulates cortical excitability and plasticity Ann Neurol. 2018 02; 83(2):352-362. . View in PubMed

The Future of Surgical Treatments for Parkinson's Disease J Parkinsons Dis. 2018; 8(s1):S79-S83. . View in PubMed

Toward a Neuroscience of Adult Cognitive Developmental Theory Front Neurosci. 2018; 12:4. . View in PubMed

Review of the Neural Oscillations Underlying Meditation Front Neurosci. 2018; 12:178. . View in PubMed

Current Status of Deep Brain Stimulation for Alzheimer's Disease: From Chance Observation to Clinical Trials Cold Spring Harb Symp Quant Biol. 2018; 83:201-205. . View in PubMed

Effect of Stereoscopic Anaglyphic 3-Dimensional Video Didactics on Learning Neuroanatomy World Neurosurg. 2017 Nov; 107:35-39. . View in PubMed

Mycobacterium Genavense Granuloma Mimicking a Brain Tumor: A Case Report Cureus. 2017 Aug 07; 9(8):e1547. . View in PubMed

Temporary stabilization of unstable spine fractures Curr Rev Musculoskelet Med. 2017 Jun; 10(2):199-206. . View in PubMed

Stimulation of the medial septum improves performance in spatial learning following pilocarpine-induced status epilepticus Epilepsy Res. 2017 02; 130:53-63. . View in PubMed

Management and outcome of spontaneous cerebral venous sinus thrombosis in a 5-year consecutive single-institution cohort J Neurointerv Surg. 2017 Jan; 9(1):34-38. . View in PubMed

Cost Utility Analysis of the Cervical Artificial Disc vs Fusion for the Treatment of 2-Level Symptomatic Degenerative Disc Disease: 5-Year Follow-up Neurosurgery. 2016 Jul; 79(1):135-45. . View in PubMed

Stereotactic guidance for navigated percutaneous sacroiliac joint fusion J Biomed Res. 2016 Mar; 30(2):162-167. . View in PubMed

Making Waves in the Brain: What Are Oscillations, and Why Modulating Them Makes Sense for Brain Injury Front Syst Neurosci. 2016; 10:30. . View in PubMed

Septohippocampal Neuromodulation Improves Cognition after Traumatic Brain Injury J Neurotrauma. 2015 Nov 15; 32(22):1822-32. . View in PubMed

Dysphagia Secondary to Anterior Osteophytes of the Cervical Spine Global Spine J. 2015 Oct; 5(5):e78-83. . View in PubMed

Commentary on: "Postoperative Shingles Mimicking Recurrent Radiculopathy after Anterior Cervical Diskectomy and Fusion" Global Spine J. 2015 Jun; 5(3):224. . View in PubMed

Intraoperative computed tomography for intracranial electrode implantation surgery in medically refractory epilepsy J Neurosurg. 2015 Mar; 122(3):526-31. . View in PubMed

Antegrade rheolytic thrombectomy and thrombolysis for superior sagittal sinus thrombosis using burr hole access J Neurointerv Surg. 2015 Mar; 7(3):e11. . View in PubMed

Intradural extramedullary capillary hemangioma of the cauda equina: Case report and literature review Surg Neurol Int. 2015; 6(Suppl 3):S127-31. . View in PubMed

Intracerebroventricular opiate infusion for refractory head and facial pain World J Clin Cases. 2014 Aug 16; 2(8):351-6. . View in PubMed

Antegrade rheolytic thrombectomy and thrombolysis for superior sagittal sinus thrombosis using burr hole access BMJ Case Rep. 2014 Apr 01; 2014. . View in PubMed

A comparative study of human and rat hippocampal low-frequency oscillations during spatial navigation Hippocampus. 2013 Aug; 23(8):656-661. . View in PubMed

Medial septal nucleus theta frequency deep brain stimulation improves spatial working memory after traumatic brain injury J Neurotrauma. 2013 Jan 15; 30(2):131-9. . View in PubMed

Frontal bur hole through an eyebrow incision for image-guided endoscopic evacuation of spontaneous intracerebral hemorrhage J Neurosurg. 2012 Oct; 117(4):767-73. . View in PubMed

Decreased expression of the glial water channel aquaporin-4 in the intrahippocampal kainic acid model of epileptogenesis Exp Neurol. 2012 May; 235(1):246-55. . View in PubMed

Aquaporin-4-dependent edema clearance following status epilepticus Epilepsy Res. 2012 Feb; 98(2-3):264-8. . View in PubMed

Robert Bentley Todd's contribution to cell theory and the neuron doctrine J Hist Neurosci. 2011 Apr; 20(2):123-34. . View in PubMed

Characterization of inpatient moyamoya in the United States: 1988-2004 Front Neurol. 2011; 2:43. . View in PubMed

Factors predicting language lateralization in patients with perisylvian vascular malformationsClinical article. J Neurosurg. 2010 Oct; 113(4):723-30. . View in PubMed

Isolated amygdala neurocysticercosis in a patient presenting with déjà vu and olfactory aurasCase report. J Neurosurg Pediatr. 2009 Jun; 3(6):538-41. . View in PubMed

Intra-arterial calcium channel blocker infusion for treatment of severe vasospasm in traumatic brain injury: case report Neurosurgery. 2008 Nov; 63(5):E1004-6; discussion E1006. . View in PubMed

An algorithm for extracting intracranial pressure latency relative to electrocardiogram R wave Physiol Meas. 2008 Apr; 29(4):459-71. . View in PubMed

Mathematical models of cerebral hemodynamics for detection of vasospasm in major cerebral arteries Acta Neurochir Suppl. 2008; 102:63-9. . View in PubMed

Morphological changes of intracranial pressure pulses are correlated with acute dilatation of ventricles Acta Neurochir Suppl. 2008; 102:131-6. . View in PubMed

Potential role of the glial water channel aquaporin-4 in epilepsy Neuron Glia Biol. 2007 Nov; 3(4):287-97. . View in PubMed

Microinfusion into the rat brain of antibodies against Semliki Forest Virus produces changes in behavioral response to apomorphine J Neuroimmunol. 2007 Mar; 184(1-2):149-55. . View in PubMed

Intradural Chordoma of Cerebellopontine Angle: Case Report and ReviewWorld Neurosurg. 2017 Nov; 107:1052. e11-1052. e16. . View in PubMed

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Gisele Ragusa

Gisele Ragusa

Constantine Sideris

Constantine Sideris