The NIH’s new Genomic Data Sharing Policy, issued on August 27, 2014, has gone into effect, beginning with grant applications submitted for the January 25, 2015 due date. Applicants are expected to state in the cover letter when a proposed study will generate large-scale human and/or nonhuman genomic data, and include a genomic data sharing plan in the application, according to a reminder notice issued December 4, 2014 (http://grants.nih.gov/grants/guide/notice-files/NOT-OD-15-027.html). If sharing of human data is not possible, applicants should provide a justification explaining why data sharing is not possible and provide an alternative data-sharing plan.