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RNA splicing is responsive to MBNL1 dose PLoS One. 2012; 7(11):e48825. . View in PubMed

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Expanded CUG repeats Dysregulate RNA splicing by altering the stoichiometry of the muscleblind 1 complex J Biol Chem. 2011 Nov 04; 286(44):38427-38438. . View in PubMed

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Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells Aging (Albany NY). 2011 Apr; 3(4):395-406. . View in PubMed

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Muscleblind-like 1 (Mbnl1) promotes insulin receptor exon 11 inclusion via binding to a downstream evolutionarily conserved intronic enhancer J Biol Chem. 2010 Aug 13; 285(33):25426-37. . View in PubMed

Muscleblind1, but not Dmpk or Six5, contributes to a complex phenotype of muscular and motivational deficits in mouse models of myotonic dystrophy PLoS One. 2010 Mar 25; 5(3):e9857. . View in PubMed

Altered nuclear functions in progeroid syndromes: a paradigm for aging research ScientificWorldJournal. 2009 Dec 16; 9:1449-62. . View in PubMed

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Perturbation of wild-type lamin A metabolism results in a progeroid phenotype Aging Cell. 2008 Jun; 7(3):355-67. . View in PubMed

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Cytoplasmic CUG RNA foci are insufficient to elicit key DM1 features PLoS One. 2008; 3(12):e3968. . View in PubMed

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Decreased expression of DMPK: correlation with CTG repeat expansion and fibre type composition in myotonic dystrophy type 1 Neurol Sci. 2005 Oct; 26(4):235-42. . View in PubMed

Myotonia and muscle contractile properties in mice with SIX5 deficiency Muscle Nerve. 2005 Apr; 31(4):503-5. . View in PubMed

Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum J Biol Chem. 2005 Mar 04; 280(9):8016-21. . View in PubMed

MBNL1 is the primary determinant of focus formation and aberrant insulin receptor splicing in DM1 J Biol Chem. 2005 Feb 18; 280(7):5773-80. . View in PubMed

In situ hybridization analysis of Dmpk mRNA in adult mouse tissues Neuromuscul Disord. 2004 Sep; 14(8-9):497-506. . View in PubMed

Six5 is required for spermatogenic cell survival and spermiogenesis Hum Mol Genet. 2004 Jul 15; 13(14):1421-31. . View in PubMed

Abnormal Na channel gating in murine cardiac myocytes deficient in myotonic dystrophy protein kinase Physiol Genomics. 2003 Jan 15; 12(2):147-57. . View in PubMed

Characterization of cardiac conduction system abnormalities in mice with targeted disruption of Six5 gene J Interv Card Electrophysiol. 2002 Oct; 7(2):127-35. . View in PubMed

Effects of age and gene dose on skeletal muscle sodium channel gating in mice deficient in myotonic dystrophy protein kinase Muscle Nerve. 2002 Jun; 25(6):850-7. . View in PubMed

Skeletal muscle Na currents in mice heterozygous for Six5 deficiency Physiol Genomics. 2001 Aug 28; 6(3):153-8. . View in PubMed

RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1 J Biol Chem. 2001 Mar 16; 276(11):7820-6. . View in PubMed

Skeletal muscle sodium channel gating in mice deficient in myotonic dystrophy protein kinase Hum Mol Genet. 2000 Sep 22; 9(15):2313-20. . View in PubMed

Progressive atrioventricular conduction block in a mouse myotonic dystrophy model J Interv Card Electrophysiol. 2000 Jun; 4(2):351-8. . View in PubMed

Heterozygous loss of Six5 in mice is sufficient to cause ocular cataracts Nat Genet. 2000 May; 25(1):110-4. . View in PubMed

Localization of the sites of conduction abnormalities in a mouse model of myotonic dystrophy J Cardiovasc Electrophysiol. 1999 Sep; 10(9):1214-20. . View in PubMed

DMPK dosage alterations result in atrioventricular conduction abnormalities in a mouse myotonic dystrophy model J Clin Invest. 1999 Feb; 103(4):R1-7. . View in PubMed

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Altered phosphorylation and intracellular distribution of a (CUG)n triplet repeat RNA-binding protein in patients with myotonic dystrophy and in myotonin protein kinase knockout mice Proc Natl Acad Sci U S A. 1997 Nov 25; 94(24):13221-6. . View in PubMed

Mice lacking the myotonic dystrophy protein kinase develop a late onset progressive myopathy Nat Genet. 1996 Jul; 13(3):325-35. . View in PubMed