Faculty2016-07-08T07:55:56-07:00

Faculty

Qilong Ying

Qilong Ying

Professor of Stem Cell Biology and Regenerative Medicine
Medicine
BCC 512 1425 San Pablo Street Health Sciences Campus Los Angeles

International Society for Stem Cell Research: McEwen Award for Innovation, 2016

University of Southern California: Phi Kappa Phi Faculty Award, 2011

Relationship of PSC to embryos: Extending and refining capture of PSC lines from mammalian embryos Bioessays. 2024 Oct 14; e2400077. . View in PubMed

Kcnh2 deletion is associated with rat embryonic development defects via destruction of KCNH2-integrin ß1 complex Int J Mol Med. 2024 02; 53(2). . View in PubMed

A novel chemical genetic approach reveals paralog-specific role of ERK1/2 in mouse embryonic stem cell fate control Front Cell Dev Biol. 2024; 12:1415621. . View in PubMed

Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids bioRxiv. 2023 May 25. . View in PubMed

ERG1 plays an essential role in rat cardiomyocyte fate decision by mediating AKT signaling Stem Cells. 2021 04; 39(4):443-457. . View in PubMed

An optimized proliferation system of embryonic stem cells for generating the rat model with large fragment modification Biochem Biophys Res Commun. 2021 09 24; 571:8-13. . View in PubMed

Laminin promotes differentiation of rat embryonic stem cells into cardiomyocytes by activating the integrin/FAK/PI3K p85 pathway J Cell Mol Med. 2019 05; 23(5):3629-3640. . View in PubMed

Cytoplasmic and Nuclear TAZ Exert Distinct Functions in Regulating Primed Pluripotency Stem Cell Reports. 2017 09 12; 9(3):732-741. . View in PubMed

The Art of Capturing Pluripotency: Creating the Right Culture Stem Cell Reports. 2017 06 06; 8(6):1457-1464. . View in PubMed

A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3a and GSK3ß in Regulating Embryonic Stem Cell FateDev Cell. 2017 12 04; 43(5):563-576. e4. . View in PubMed

Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90a) to Survive a Hostile Hypoxic Environment Sci Rep. 2016 Feb 05; 6:20605. . View in PubMed

Wnt/ß-catenin and LIF-Stat3 signaling pathways converge on Sp5 to promote mouse embryonic stem cell self-renewal J Cell Sci. 2016 Jan 15; 129(2):269-76. . View in PubMed

Efficient Assessment of Developmental, Surgical and Pathological Lymphangiogenesis Using a Lymphatic Reporter Mouse and Its Embryonic Stem Cells PLoS One. 2016; 11(6):e0157126. . View in PubMed

Stem cell maintenance by manipulating signaling pathways: past, current and future BMB Rep. 2015 Dec; 48(12):668-76. . View in PubMed

New insights into the conserved mechanism of pluripotency maintenance Curr Opin Genet Dev. 2015 Oct; 34:1-9. . View in PubMed

Klf2 and Tfcp2l1, Two Wnt/ß-Catenin Targets, Act Synergistically to Induce and Maintain Naive Pluripotency Stem Cell Reports. 2015 Sep 08; 5(3):314-22. . View in PubMed

The stromal genome heterogeneity between breast and prostate tumors revealed by a comparative transcriptomic analysis Oncotarget. 2015 Apr 20; 6(11):8687-97. . View in PubMed

Dual Function of Wnt Signaling during Neuronal Differentiation of Mouse Embryonic Stem Cells Stem Cells Int. 2015; 2015:459301. . View in PubMed

Fluoxetine regulates neurogenesis in vitro through modulation of GSK-3ß/ß-catenin signaling Int J Neuropsychopharmacol. 2014 Dec 07; 18(5). . View in PubMed

Signaling pathways in induced naïve pluripotency Curr Opin Genet Dev. 2014 Oct; 28:10-5. . View in PubMed

Stat3 signaling regulates embryonic stem cell fate in a dose-dependent manner Biol Open. 2014 Sep 19; 3(10):958-65. . View in PubMed

STAT3 phosphorylation at tyrosine 705 and serine 727 differentially regulates mouse ESC fates Stem Cells. 2014 May; 32(5):1149-60. . View in PubMed

Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1 EMBO J. 2013 Oct 02; 32(19):2548-60. . View in PubMed

p53 promotes inflammation-associated hepatocarcinogenesis by inducing HMGB1 release J Hepatol. 2013 Oct; 59(4):762-8. . View in PubMed

Induced neural stem cells generated from rat fibroblasts Genomics Proteomics Bioinformatics. 2013 Oct; 11(5):312-9. . View in PubMed

DNA damage-induced sustained p53 activation contributes to inflammation-associated hepatocarcinogenesis in rats Oncogene. 2013 Sep 19; 32(38):4565-71. . View in PubMed

Gbx2, a LIF/Stat3 target, promotes reprogramming to and retention of the pluripotent ground state J Cell Sci. 2013 Mar 01; 126(Pt 5):1093-8. . View in PubMed

Modulation of ß-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal Nat Commun. 2013; 4:2403. . View in PubMed

Rats deficient for p53 are susceptible to spontaneous and carcinogen-induced tumorigenesis Carcinogenesis. 2012 Oct; 33(10):2001-5. . View in PubMed

Rapid and cost-effective gene targeting in rat embryonic stem cells by TALENs J Genet Genomics. 2012 Jun 20; 39(6):275-80. . View in PubMed

Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains PLoS One. 2012; 7(4):e35892. . View in PubMed

Monoamine oxidase A regulates neural differentiation of murine embryonic stem cells J Neural Transm (Vienna). 2011 Jul; 118(7):997-1001. . View in PubMed

Genetic manipulations in the rat: progress and prospects Curr Opin Nephrol Hypertens. 2011 Jul; 20(4):391-9. . View in PubMed

Generating gene knockout rats by homologous recombination in embryonic stem cells Nat Protoc. 2011 Jun; 6(6):827-44. . View in PubMed

Beyond knockout rats: new insights into finer genome manipulation in rats Cell Cycle. 2011 Apr 01; 10(7):1059-66. . View in PubMed

Production of p53 gene knockout rats by homologous recombination in embryonic stem cells Nature. 2010 Sep 09; 467(7312):211-3. . View in PubMed

Germline competent embryonic stem cells derived from rat blastocysts Cell. 2008 Dec 26; 135(7):1299-310. . View in PubMed

The ground state of embryonic stem cell self-renewal Nature. 2008 May 22; 453(7194):519-23. . View in PubMed

[Isolation and purification of human neutrophil elastase] Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1986 Oct; 8(5):376-81. . View in PubMed

Geographical variability of alpha-1-antitrypsin alleles in China: a study on six Chinese populations Hum Genet. 1985; 69(2):184-7. . View in PubMed

Alpha-1-antitrypsin types in five Chinese national minorities Hum Genet. 1985; 71(3):225-6. . View in PubMed

The gene frequency of serum albumin variants in Chinese and the electrophoretic characterization of several serum albumin variants Sci Sin. 1981 Nov; 24(11):1597-602. . View in PubMed

[Studies on polymorphisms of blood proteins in Chinese populationsII. Study on polymorphism of serum transferrin in Chinese (author's transl)]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1981 Mar; 3(1):1-5. . View in PubMed

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