Faculty
Peter Kuhn
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Blood-based liquid biopsy: A promising noninvasive test in diagnosis, surveillance, and prognosis of patients with upper tract urothelial carcinomaUrol Oncol. 2024 04; 42(4):118. e9-118. e17. . View in PubMed
Phenotypic Biomarkers of Aqueous Extracellular Vesicles from Retinoblastoma Eyes Int J Mol Sci. 2024 Oct 30; 25(21). . View in PubMed
Polyploid cancer cells reveal signatures of chemotherapy resistance Res Sq. 2024 Oct 14. . View in PubMed
Circulation of rare events in the liquid biopsy for early detection of lung mass lesions Thorac Cancer. 2024 Oct; 15(29):2100-2109. . View in PubMed
Lexicon for blood-based early detection and screening: BLOODPAC consensus document Clin Transl Sci. 2024 Sep; 17(9):e70016. . View in PubMed
Polyploid cancer cells reveal signatures of chemotherapy resistance bioRxiv. 2024 Aug 23. . View in PubMed
Single-cell somatic copy number alteration profiling of vitreous humor seeds in retinoblastoma Ophthalmic Genet. 2024 Jul 17; 1-4. . View in PubMed
Cells in the Polyaneuploid Cancer Cell State are Pro-Metastatic bioRxiv. 2024 Jul 16. . View in PubMed
Determining the efficacy of ExThera Seraph100 blood filtration in patients diagnosed with pancreatic cancer through the liquid biopsy BJC Rep. 2024 Jun 27; 2(1):47. . View in PubMed
PSCA-CAR T cell therapy in metastatic castration-resistant prostate cancer: a phase 1 trial Nat Med. 2024 Jun; 30(6):1636-1644. . View in PubMed
Longitudinal tracking of circulating rare events in the liquid biopsy of stage III-IV non-small cell lung cancer patients Discov Oncol. 2024 May 03; 15(1):142. . View in PubMed
A Systematic Approach toward Enabling Maximal Targeting Efficiency of Cell Surface Proteins with Actively Targeted SERS Nanoparticles ACS Appl Mater Interfaces. 2024 Apr 03; 16(13):15847-15860. . View in PubMed
Cancer-related cells and oncosomes in the liquid biopsy of pancreatic cancer patients undergoing surgery NPJ Precis Oncol. 2024 Feb 15; 8(1):36. . View in PubMed
Liquid biopsy approach to monitor the efficacy and response to CAR-T cell therapy J Immunother Cancer. 2024 Feb 12; 12(2). . View in PubMed
Aqueous Humor Liquid Biopsy as a Companion Diagnostic for Retinoblastoma: Implications for Diagnosis, Prognosis, and Therapeutic Options: Five Years of Progress Am J Ophthalmol. 2024 07; 263:188-205. . View in PubMed
Targeted single-cell proteomic analysis identifies new liquid biopsy biomarkers associated with multiple myeloma NPJ Precis Oncol. 2023 Sep 18; 7(1):95. . View in PubMed
Cell State and Cell Type: Deconvoluting Circulating Tumor Cell Populations in Liquid Biopsies by Multi-Omics Cancers (Basel). 2023 Aug 03; 15(15). . View in PubMed
Simultaneous Copy Number Alteration and Single-Nucleotide Variation Analysis in Matched Aqueous Humor and Tumor Samples in Children with Retinoblastoma Int J Mol Sci. 2023 May 11; 24(10). . View in PubMed
Profile of the multicenter cohort of the German Cancer Consortium's Clinical Communication Platform Eur J Epidemiol. 2023 May; 38(5):573-586. . View in PubMed
Investigation of liquid biopsy analytes in peripheral blood of individuals after SARS-CoV-2 infection EBioMedicine. 2023 Apr; 90:104519. . View in PubMed
BLOODPAC: Collaborating to chart a path towards blood-based screening for early cancer detection Clin Transl Sci. 2023 01; 16(1):5-9. . View in PubMed
Plasticity of circulating tumor cells in small cell lung cancer Sci Rep. 2023 07 21; 13(1):11775. . View in PubMed
Single cell clonotypic and transcriptional evolution of multiple myeloma precursor diseaseCancer Cell. 2023 06 12; 41(6):1032-1047. e4. . View in PubMed
Comprehensive Single-Cell Immune Profiling Defines the Patient Multiple Myeloma Microenvironment Following Oncolytic Virus Therapy in a Phase Ib Trial Clin Cancer Res. 2023 12 15; 29(24):5087-5103. . View in PubMed
Characterization of BCMA Expression in Circulating Rare Single Cells of Patients with Plasma Cell Neoplasms Int J Mol Sci. 2022 Nov 03; 23(21). . View in PubMed
Defining A Liquid Biopsy Profile of Circulating Tumor Cells and Oncosomes in Metastatic Colorectal Cancer for Clinical Utility Cancers (Basel). 2022 Oct 06; 14(19). . View in PubMed
Multianalyte liquid biopsy to aid the diagnostic workup of breast cancer NPJ Breast Cancer. 2022 Sep 27; 8(1):112. . View in PubMed
Identification of epithelial and mesenchymal circulating tumor cells in clonal lineage of an aggressive prostate cancer case NPJ Precis Oncol. 2022 Jun 21; 6(1):41. . View in PubMed
Liquid Biopsy Landscape in Patients with Primary Upper Tract Urothelial Carcinoma Cancers (Basel). 2022 Jun 18; 14(12). . View in PubMed
Potential of Aqueous Humor as a Liquid Biopsy for Uveal Melanoma Int J Mol Sci. 2022 Jun 02; 23(11). . View in PubMed
Disease characterization in liquid biopsy from HER2-mutated, non-amplified metastatic breast cancer patients treated with neratinib NPJ Breast Cancer. 2022 Feb 18; 8(1):22. . View in PubMed
Characterization of Cellular and Acellular Analytes from Pre-Cystectomy Liquid Biopsies in Patients Newly Diagnosed with Primary Bladder Cancer Cancers (Basel). 2022 Feb 01; 14(3). . View in PubMed
Circulating Tumor Cell Kinetics and Morphology from the Liquid Biopsy Predict Disease Progression in Patients with Metastatic Colorectal Cancer Following Resection Cancers (Basel). 2022 Jan 27; 14(3). . View in PubMed
Chromosome 6p amplification detected in blood cell-free DNA in advanced intraocular retinoblastoma Ophthalmic Genet. 2022 12; 43(6):866-870. . View in PubMed
Early detection of cancer Science. 2022 03 18; 375(6586):eaay9040. . View in PubMed
Single-cell spatial analysis of tumor immune architecture in diffuse large B-cell lymphoma Blood Adv. 2022 08 23; 6(16):4675-4690. . View in PubMed
Enrichment-Free Single-Cell Detection and Morphogenomic Profiling of Myeloma Patient Samples to Delineate Circulating Rare Plasma Cell Clones Curr Oncol. 2022 04 21; 29(5):2954-2972. . View in PubMed
A Randomized Trial of Fulvestrant, Everolimus, and Anastrozole for the Front-line Treatment of Patients with Advanced Hormone Receptor-positive Breast Cancer, SWOG S1222 Clin Cancer Res. 2022 02 15; 28(4):611-617. . View in PubMed
Early Breast Cancer Evolution by Autosomal Broad Copy Number Alterations Int J Genomics. 2022; 2022:9332922. . View in PubMed
Prediction of Metastatic Patterns in Bladder Cancer: Spatiotemporal Progression and Development of a Novel, Web-based Platform for Clinical Utility Eur Urol Open Sci. 2021 Oct; 32:8-18. . View in PubMed
Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy NPJ Precis Oncol. 2021 Jul 27; 5(1):73. . View in PubMed
Comprehensive Somatic Copy Number Analysis Using Aqueous Humor Liquid Biopsy for Retinoblastoma Cancers (Basel). 2021 Jul 03; 13(13). . View in PubMed
Health Economic Evidence for Liquid- and Tissue-based Molecular Tests that Inform Decisions on Prostate Biopsies and Treatment of Localised Prostate Cancer: A Systematic Review Eur Urol Open Sci. 2021 May; 27:77-87. . View in PubMed
Establishing the Clinical Utility of ctDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: The Aqueous Humor Liquid Biopsy Cancers (Basel). 2021 Mar 13; 13(6). . View in PubMed
Large Extracellular Vesicle Characterization and Association with Circulating Tumor Cells in Metastatic Castrate Resistant Prostate Cancer Cancers (Basel). 2021 Mar 02; 13(5). . View in PubMed
Platelet-Coated Circulating Tumor Cells Are a Predictive Biomarker in Patients with Metastatic Castrate-Resistant Prostate Cancer Mol Cancer Res. 2021 12; 19(12):2036-2045. . View in PubMed
Modeling the onset of symptoms of COVID-19: Effects of SARS-CoV-2 variant PLoS Comput Biol. 2021 12; 17(12):e1009629. . View in PubMed
Model Development of CDK4/6 Predicted Efficacy in Patients With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced or Metastatic Breast Cancer JCO Clin Cancer Inform. 2021 06; 5:758-767. . View in PubMed
Aqueous Humor as a Liquid Biopsy for Retinoblastoma: Clear Corneal Paracentesis and Genomic Analysis J Vis Exp. 2021 09 07; (175). . View in PubMed
Patient Empowerment During the COVID-19 Pandemic by Ensuring Safe and Fast Communication of Test Results: Implementation and Performance of a Tracking System J Med Internet Res. 2021 06 07; 23(6):e27348. . View in PubMed
Liquid Biopsy in Colorectal Carcinoma: Clinical Applications and Challenges Cancers (Basel). 2020 May 27; 12(6). . View in PubMed
Simultaneous identification of clinically relevant RB1 mutations and copy number alterations in aqueous humor of retinoblastoma eyes Ophthalmic Genet. 2020 12; 41(6):526-532. . View in PubMed
Treatment response and tumor evolution: lessons from an extended series of multianalyte liquid biopsies in a metastatic breast cancer patient Cold Spring Harb Mol Case Stud. 2020 12; 6(6). . View in PubMed
Phase Ib Study of Enzalutamide with or Without Sorafenib in Patients with Advanced Hepatocellular Carcinoma Oncologist. 2020 12; 25(12):e1825-e1836. . View in PubMed
Variability in retinoblastoma genome stability is driven by age and not heritability Genes Chromosomes Cancer. 2020 10; 59(10):584-590. . View in PubMed
Cell-Free DNA Tumor Fraction in the Aqueous Humor Is Associated With Therapeutic Response in Retinoblastoma Patients Transl Vis Sci Technol. 2020 09; 9(10):30. . View in PubMed
Use of Wearable Activity Tracker in Patients With Cancer Undergoing Chemotherapy: Toward Evaluating Risk of Unplanned Health Care Encounters JCO Clin Cancer Inform. 2020 09; 4:839-853. . View in PubMed
Chromosome 6p Amplification in Aqueous Humor Cell-Free DNA Is a Prognostic Biomarker for Retinoblastoma Ocular Survival Mol Cancer Res. 2020 08; 18(8):1166-1175. . View in PubMed
Quantified Kinematics to Evaluate Patient Chemotherapy Risks in Clinic JCO Clin Cancer Inform. 2020 06; 4:583-601. . View in PubMed
Aqueous Humor Is Superior to Blood as a Liquid Biopsy for Retinoblastoma Ophthalmology. 2020 04; 127(4):552-554. . View in PubMed
Minimum Technical Data Elements for Liquid Biopsy Data Submitted to Public Databases Clin Pharmacol Ther. 2020 04; 107(4):730-734. . View in PubMed
Preanalytical Variables for the Genomic Assessment of the Cellular and Acellular Fractions of the Liquid Biopsy in a Cohort of Breast Cancer Patients J Mol Diagn. 2020 03; 22(3):319-337. . View in PubMed
Feasibility of a large multi-center translational research project for newly diagnosed breast and ovarian cancer patients with affiliated biobank: the BRandO biology and outcome (BiO)-project Arch Gynecol Obstet. 2020 01; 301(1):273-281. . View in PubMed
Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes J Am Chem Soc. 2020 09 30; 142(39):16704-16715. . View in PubMed
Modeling the Onset of Symptoms of COVID-19 Front Public Health. 2020; 8:473. . View in PubMed
Single-Cell Circulating Tumor Cell Analysis Reveals Genomic Instability as a Distinctive Feature of Aggressive Prostate Cancer Clin Cancer Res. 2020 08 01; 26(15):4143-4153. . View in PubMed
Circulating Tumor Cells: High-Throughput Imaging of CTCs and Bioinformatic Analysis Recent Results Cancer Res. 2020; 215:89-104. . View in PubMed
Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer Oncotarget. 2019 Dec 17; 10(66):7016-7030. . View in PubMed
Patient reported outcomes can improve performance status assessment: a pilot study J Patient Rep Outcomes. 2019 Jul 16; 3(1):41. . View in PubMed
Prediction of Bone Metastasis in Inflammatory Breast Cancer Using a Markov Chain Model Oncologist. 2019 10; 24(10):1322-1330. . View in PubMed
Randomized Phase II Trial of Abiraterone Alone or With Dasatinib in Men With Metastatic Castration-resistant Prostate Cancer (mCRPC)Clin Genitourin Cancer. 2019 08; 17(4):241-247. e1. . View in PubMed
Histological Validation of 11Carbon-Acetate Positron Emission Tomography/Computerized Tomography in Detecting Lymph Node Metastases in Prostate Cancer J Urol. 2019 02; 201(2):332-341. . View in PubMed
Circulating tumor cells as a response monitor in stage IV non-small cell lung cancer J Transl Med. 2019 08 28; 17(1):294. . View in PubMed
A new anion exchange purification method for Cu stable isotopes in blood samples Anal Bioanal Chem. 2019 Jan; 411(3):765-776. . View in PubMed
Machine learning models for predicting post-cystectomy recurrence and survival in bladder cancer patients PLoS One. 2019; 14(2):e0210976. . View in PubMed
Single-Cell Analysis of Circulating Tumor Cells Methods Mol Biol. 2019; 1908:243-264. . View in PubMed
Multiplex protein detection on circulating tumor cells from liquid biopsies using imaging mass cytometry Converg Sci Phys Oncol. 2018 Mar; 4(1). . View in PubMed
Clonal diversity revealed by morphoproteomic and copy number profiles of single prostate cancer cells at diagnosis Converg Sci Phys Oncol. 2018 Mar; 4(1). . View in PubMed
Effect of Blood Collection Tube Type and Time to Processing on the Enumeration and High-Content Characterization of Circulating Tumor Cells Using the High-Definition Single-Cell Assay Arch Pathol Lab Med. 2018 Feb; 142(2):198-207. . View in PubMed
Genomic cfDNA Analysis of Aqueous Humor in Retinoblastoma Predicts Eye Salvage: The Surrogate Tumor Biopsy for Retinoblastoma Mol Cancer Res. 2018 11; 16(11):1701-1712. . View in PubMed
Low-dimensional dynamical characterization of human performance of cancer patients using motion data Clin Biomech (BristolAvon). 2018 07; 56:61-69. . View in PubMed
Prostate Cancer Disseminated Tumor Cells are Rarely Detected in the Bone Marrow of Patients with Localized Disease Undergoing Radical Prostatectomy across Multiple Rare Cell Detection Platforms J Urol. 2018 06; 199(6):1494-1501. . View in PubMed
Opportunities and Challenges in Implementation of Multiparameter Single Cell Analysis Platforms for Clinical Translation Clin Transl Sci. 2018 05; 11(3):267-276. . View in PubMed
Development of metastatic brain disease involves progression through lung metastases in EGFR mutated non-small cell lung cancer Converg Sci Phys Oncol. 2017 Sep; 3(3). . View in PubMed
Robotic salvage retroperitoneal and pelvic lymph node dissection for 'node-only' recurrent prostate cancer: technique and initial series BJU Int. 2017 09; 120(3):401-408. . View in PubMed
Potential of Aqueous Humor as a Surrogate Tumor Biopsy for Retinoblastoma JAMA Ophthalmol. 2017 11 01; 135(11):1221-1230. . View in PubMed
Paired High-Content Analysis of Prostate Cancer Cells in Bone Marrow and Blood Characterizes Increased Androgen Receptor Expression in Tumor Cell Clusters Clin Cancer Res. 2017 04 01; 23(7):1722-1732. . View in PubMed
The prothrombotic activity of cancer cells in the circulation Blood Rev. 2016 Jan; 30(1):11-9. . View in PubMed
Vasculogenic mimicry in small cell lung cancer Nat Commun. 2016 11 09; 7:13322. . View in PubMed
A Multicenter, Open-Label Phase II Clinical Trial of Combined MEK plus EGFR Inhibition for Chemotherapy-Refractory Advanced Pancreatic Adenocarcinoma Clin Cancer Res. 2016 Jan 01; 22(1):61-8. . View in PubMed
A physical sciences network characterization of circulating tumor cell aggregate transport Am J Physiol Cell Physiol. 2015 May 15; 308(10):C792-802. . View in PubMed
Fourier-ring descriptor to characterize rare circulating cells from images generated using immunofluorescence microscopy Comput Med Imaging Graph. 2015 Mar; 40:70-87. . View in PubMed
The thrombotic potential of circulating tumor microemboli: computational modeling of circulating tumor cell-induced coagulation Am J Physiol Cell Physiol. 2015 Feb 01; 308(3):C229-36. . View in PubMed
Limited genomic heterogeneity of circulating melanoma cells in advanced stage patients Phys Biol. 2015 Jan 09; 12(1):016008. . View in PubMed
Distinctive Structure of the EphA3/Ephrin-A5 Complex Reveals a Dual Mode of Eph Receptor Interaction for Ephrin-A5 PLoS One. 2015; 10(5):e0127081. . View in PubMed
Spatiotemporal progression of metastatic breast cancer: a Markov chain model highlighting the role of early metastatic sites NPJ Breast Cancer. 2015; 1:15018. . View in PubMed
Entropy, complexity, and Markov diagrams for random walk cancer models Sci Rep. 2014 Dec 19; 4:7558. . View in PubMed
Advancing cancer patient care by integrating circulating tumor cell technology to understand the spatial and temporal dynamics of cancer Drug Dev Res. 2014 Sep; 75(6):384-92. . View in PubMed
Circulating tumor microemboli diagnostics for patients with non-small-cell lung cancer J Thorac Oncol. 2014 Aug; 9(8):1111-9. . View in PubMed
Adrenal metastases in lung cancer: clinical implications of a mathematical model J Thorac Oncol. 2014 Apr; 9(4):442-6. . View in PubMed
Fluid phase biopsy for detection and characterization of circulating endothelial cells in myocardial infarction Phys Biol. 2014 Feb; 11(1):016002. . View in PubMed
Physical biology in cancer2. The physical biology of circulating tumor cells. Am J Physiol Cell Physiol. 2014 Jan 15; 306(2):C80-8. . View in PubMed
Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells PLoS One. 2014; 9(8):e101777. . View in PubMed
Spreaders and sponges define metastasis in lung cancer: a Markov chain Monte Carlo mathematical model Cancer Res. 2013 May 01; 73(9):2760-9. . View in PubMed
The GPCR Network: a large-scale collaboration to determine human GPCR structure and function Nat Rev Drug Discov. 2013 01; 12(1):25-34. . View in PubMed
A physical sciences network characterization of non-tumorigenic and metastatic cells Sci Rep. 2013; 3:1449. . View in PubMed
An observational study of circulating tumor cells and (18)F-FDG PET uptake in patients with treatment-naive non-small cell lung cancer PLoS One. 2013; 8(7):e67733. . View in PubMed
Circulating tumor cells in non-small cell lung carcinoma J Thorac Dis. 2012 Oct; 4(5):456-8. . View in PubMed
Fluid biopsy for solid tumors: a patient's companion for lifelong characterization of their disease Future Oncol. 2012 Aug; 8(8):989-98. . View in PubMed
Characterization of circulating endothelial cells in acute myocardial infarction Sci Transl Med. 2012 Mar 21; 4(126):126ra33. . View in PubMed
Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3731-6. . View in PubMed
Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers Phys Biol. 2012 Feb; 9(1):016003. . View in PubMed
A fluid biopsy as investigating technology for the fluid phase of solid tumors Phys Biol. 2012 Feb; 9(1):010301. . View in PubMed
High-definition imaging of circulating tumor cells and associated cellular events in non-small cell lung cancer patients: a longitudinal analysis Phys Biol. 2012 Feb; 9(1):016004. . View in PubMed
Cytometric comparisons between circulating tumor cells from prostate cancer patients and the prostate-tumor-derived LNCaP cell line Phys Biol. 2012 Feb; 9(1):016002. . View in PubMed
Characterization of circulating tumor cell aggregates identified in patients with epithelial tumors Phys Biol. 2012 Feb; 9(1):016001. . View in PubMed
Fluid biopsy for circulating tumor cell identification in patients with early-and late-stage non-small cell lung cancer: a glimpse into lung cancer biology Phys Biol. 2012 Feb; 9(1):016005. . View in PubMed
A stochastic Markov chain model to describe lung cancer growth and metastasis PLoS One. 2012; 7(4):e34637. . View in PubMed
Quantification of cellular volume and sub-cellular density fluctuations: comparison of normal peripheral blood cells and circulating tumor cells identified in a breast cancer patient Front Oncol. 2012; 2:96. . View in PubMed
Optical quantification of cellular mass, volume, and density of circulating tumor cells identified in an ovarian cancer patient Front Oncol. 2012; 2:72. . View in PubMed
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists Science. 2010 Nov 19; 330(6007):1066-71. . View in PubMed
Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10708-12. . View in PubMed
Serotype-specific structural differences in the protease-cofactor complexes of the dengue virus family J Virol. 2010 Mar; 84(6):3059-67. . View in PubMed
Cytomorphology of circulating colorectal tumor cells:a small case series J Oncol. 2010; 2010:861341. . View in PubMed
Nuclear magnetic resonance structure of the nucleic acid-binding domain of severe acute respiratory syndrome coronavirus nonstructural protein 3 J Virol. 2009 Dec; 83(24):12998-3008. . View in PubMed
Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam J R Soc Interface. 2009 Oct 06; 6 Suppl 5:S587-97. . View in PubMed
Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling J Virol. 2009 Oct; 83(19):10314-8. . View in PubMed
Circulating tumor cells from well-differentiated lung adenocarcinoma retain cytomorphologic features of primary tumor type Arch Pathol Lab Med. 2009 Sep; 133(9):1468-71. . View in PubMed
Mutations in LOXHD1, an evolutionarily conserved stereociliary protein, disrupt hair cell function in mice and cause progressive hearing loss in humans Am J Hum Genet. 2009 Sep; 85(3):328-37. . View in PubMed
A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells Proc Natl Acad Sci U S A. 2009 Mar 31; 106(13):5252-7. . View in PubMed
Nuclear magnetic resonance structure shows that the severe acute respiratory syndrome coronavirus-unique domain contains a macrodomain fold J Virol. 2009 Feb; 83(4):1823-36. . View in PubMed
Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1 J Mol Biol. 2008 Jul 25; 380(5):828-43. . View in PubMed
Enthalpy array analysis of enzymatic and binding reactions Anal Biochem. 2008 Jun 01; 377(1):33-9. . View in PubMed
Proteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3 J Virol. 2008 Jun; 82(11):5279-94. . View in PubMed
A specific cholesterol binding site is established by the 28 A structure of the human beta2-adrenergic receptor. Structure. 2008 Jun; 16(6):897-905. . View in PubMed
C-ME: a 3D community-based, real-time collaboration tool for scientific research and training PLoS One. 2008 Feb 20; 3(2):e1621. . View in PubMed
In situ X-ray analysis of protein crystals in low-birefringent and X-ray transmissive plastic microchannels Acta Crystallogr D Biol Crystallogr. 2008 Feb; 64(Pt 2):189-97. . View in PubMed
Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition J Biol Chem. 2007 Dec 14; 282(50):36505-13. . View in PubMed
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor Science. 2007 Nov 23; 318(5854):1258-65. . View in PubMed
Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus J Virol. 2007 Nov; 81(21):12049-60. . View in PubMed
Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression Protein Expr Purif. 2007 Nov; 56(1):85-92. . View in PubMed
Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models J Virol. 2007 Jun; 81(11):5637-48. . View in PubMed
Crystal structure of a monomeric form of severe acute respiratory syndrome coronavirus endonuclease nsp15 suggests a role for hexamerization as an allosteric switch J Virol. 2007 Jun; 81(12):6700-8. . View in PubMed
Remedial strategies in structural proteomics: expression, purification, and crystallization of the Vav1/Rac1 complex Protein Expr Purif. 2007 May; 53(1):51-62. . View in PubMed
Ribonucleocapsid formation of severe acute respiratory syndrome coronavirus through molecular action of the N-terminal domain of N protein J Virol. 2007 Apr; 81(8):3913-21. . View in PubMed
Case study of the morphologic variation of circulating tumor cells Hum Pathol. 2007 Mar; 38(3):514-9. . View in PubMed
Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity J Biol Chem. 2006 Sep 22; 281(38):28185-92. . View in PubMed
Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 206 angstrom resolution. Proteins. 2006 Aug 15; 64(3):808-13. . View in PubMed
Supramolecular architecture of severe acute respiratory syndrome coronavirus revealed by electron cryomicroscopy J Virol. 2006 Aug; 80(16):7918-28. . View in PubMed
Crystal structure of nonstructural protein 10 from the severe acute respiratory syndrome coronavirus reveals a novel fold with two zinc-binding motifs J Virol. 2006 Aug; 80(16):7894-901. . View in PubMed
Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 215 A resolution. Proteins. 2006 Jun 01; 63(4):1106-11. . View in PubMed
Crystal structure of TM1367 from Thermotoga maritima at 190 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold. Proteins. 2006 Jun 01; 63(4):1112-8. . View in PubMed
High speed detection of circulating tumor cells Biosens Bioelectron. 2006 Apr 15; 21(10):1893-9. . View in PubMed
Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity Structure. 2006 Feb; 14(2):321-30. . View in PubMed
In situ data collection and structure refinement from microcapillary protein crystallization J Appl Crystallogr. 2005 Dec; 38(6):900-905. . View in PubMed
Structural basis of severe acute respiratory syndrome coronavirus ADP-ribose-1''-phosphate dephosphorylation by a conserved domain of nsP3 Structure. 2005 Nov; 13(11):1665-75. . View in PubMed
Structural genomics of the severe acute respiratory syndrome coronavirus: nuclear magnetic resonance structure of the protein nsP7 J Virol. 2005 Oct; 79(20):12905-13. . View in PubMed
Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers J Virol. 2005 Aug; 79(15):9665-76. . View in PubMed
Crystal structure of an alanine-glyoxylate aminotransferase from Anabaena spat 1. 70 A resolution reveals a noncovalently linked PLP cofactor. Proteins. 2005 Mar 01; 58(4):971-5. . View in PubMed
Crystal structure of a formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 280 A resolution reveals a new fold. Proteins. 2005 Mar 01; 58(4):976-81. . View in PubMed
Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 185 A resolution. Proteins. 2005 Feb 15; 58(3):755-8. . View in PubMed
Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 200-A resolution reveals a new fold. Proteins. 2004 Aug 15; 56(3):607-10. . View in PubMed
Crystal structure of a putative NADPH-dependent oxidoreductase (GI: 18204011) from mouse at 210 A resolution. Proteins. 2004 Aug 15; 56(3):629-33. . View in PubMed
Crystal structure of a novel manganese-containing cupin (TM1459) from Thermotoga maritima at 165 A resolution. Proteins. 2004 Aug 15; 56(3):611-4. . View in PubMed
Crystal structure of an allantoicase (YIR029W) from Saccharomyces cerevisiae at 24 A resolution. Proteins. 2004 Aug 15; 56(3):619-24. . View in PubMed
Crystal structure of a PIN (PilT N-terminus) domain (AF0591) from Archaeoglobus fulgidus at 190 A resolution. Proteins. 2004 Aug 01; 56(2):404-8. . View in PubMed
Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 19 A resolution. Proteins. 2004 Aug 01; 56(2):396-400. . View in PubMed
Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 18 A resolution. Proteins. 2004 Aug 01; 56(2):387-91. . View in PubMed
Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 160 A resolution. Proteins. 2004 Jul 01; 56(1):167-70. . View in PubMed
Crystal structure of a type II quinolic acid phosphoribosyltransferase (TM1645) from Thermotoga maritima at 250 A resolution. Proteins. 2004 May 15; 55(3):768-71. . View in PubMed
Crystal structure of an HEPN domain protein (TM0613) from Thermotoga maritima at 175 A resolution. Proteins. 2004 Mar 01; 54(4):806-9. . View in PubMed
Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 20 A resolution. Proteins. 2004 Jan 01; 54(1):157-61. . View in PubMed
Shotgun crystallization strategy for structural genomics: an optimized two-tiered crystallization screen against the Thermotoga maritima proteome Acta Crystallogr D Biol Crystallogr. 2003 Jun; 59(Pt 6):1028-37. . View in PubMed
Functional analysis of substrate and cofactor complex structures of a thymidylate synthase-complementing protein Structure. 2003 Jun; 11(6):677-90. . View in PubMed
A low-dimensional deformation model for cancer cells in flow Phys Fluids (1994). 2012 Aug; 24(8):81903. . View in PubMed