Faculty
Hooman Allayee
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Ambient air pollution exposure is associated with liver fat and stiffness in Latino youth with a more pronounced effect in those with PNPLA3 genotype and more advanced liver disease Ecotoxicol Environ Saf. 2024 Oct 24; 286:117234. . View in PubMed
COVID-19 Is a Coronary Artery Disease Risk Equivalent and Exhibits a Genetic Interaction With ABO Blood Type Arterioscler Thromb Vasc Biol. 2024 Oct 09. . View in PubMed
Reply to Guyton, JR. & Boden, W. E. ; Schreiber, S. et al. Nat Med. 2024 Sep 05. . View in PubMed
Serum proteomic profiling of physical activity reveals CD300LG as a novel exerkine with a potential causal link to glucose homeostasis Elife. 2024 Aug 27; 13. . View in PubMed
Associations of dietary sugars with liver stiffness in Latino adolescents with obesity differ on PNPLA3 and liver disease severity Liver Int. 2024 Aug; 44(8):1768-1774. . View in PubMed
Comprehensive Clinical and Genetic Analyses of Circulating Bile Acids and Their Associations With Diabetes and Its Indices Diabetes. 2024 Aug 01; 73(8):1215-1228. . View in PubMed
Publisher Correction: A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk Nat Med. 2024 Jun; 30(6):1791. . View in PubMed
Blocking CD226 regulates type 2 innate lymphoid cell effector function and alleviates airway hyperreactivityJ Allergy Clin Immunol. 2024 May; 153(5):1406-1422. e6. . View in PubMed
Effect of Hormone Therapy on Lipoprotein Subfractions in Early and Late Postmenopausal Women J Clin Endocrinol Metab. 2024 Mar 28. . View in PubMed
A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk Nat Med. 2024 Feb; 30(2):424-434. . View in PubMed
Genetics unravels protein-metabolite relationships Trends Endocrinol Metab. 2024 03; 35(3):183-184. . View in PubMed
Relationships and Mendelian Randomization of Gut Microbe-Derived Metabolites with Metabolic Syndrome Traits in the METSIM Cohort Metabolites. 2024 03 20; 14(3). . View in PubMed
Indole-3-Propionic Acid Protects Against Heart Failure With Preserved Ejection Fraction Circ Res. 2024 02 16; 134(4):371-389. . View in PubMed
Effect of Genetic and Dietary Perturbation of Glycine Metabolism on Atherosclerosis in Humans and Mice medRxiv. 2023 Dec 11. . View in PubMed
Effects of Dietary Sugar Reduction on Biomarkers of Cardiometabolic Health in Latino Youth: Secondary Analyses from a Randomized Controlled Trial Nutrients. 2023 Jul 27; 15(15). . View in PubMed
Trimethylamine N-Oxide Response to a Mixed Macronutrient Tolerance Test in a Cohort of Healthy United States Adults Int J Mol Sci. 2023 Jan 20; 24(3). . View in PubMed
Systems genetics approaches for understanding complex traits with relevance for human disease Elife. 2023 11 14; 12. . View in PubMed
Role of gut microbe-derived metabolites in cardiometabolic diseases: Systems based approach Mol Metab. 2022 10; 64:101557. . View in PubMed
Liver-heart cross-talk mediated by coagulation factor XI protects against heart failure Science. 2022 09 23; 377(6613):1399-1406. . View in PubMed
Effect of menopausal hormone therapy on methylation levels in early and late postmenopausal women Clin Epigenetics. 2022 07 18; 14(1):90. . View in PubMed
Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis Front Physiol. 2022; 13:909870. . View in PubMed
Near-roadway air pollution, immune cells and adipokines among obese young adults Environ Health. 2022 03 19; 21(1):36. . View in PubMed
Clinical Intervention to Reduce Dietary Sugar Does Not Affect Liver Fat in Latino Youth, Regardless of PNPLA3 Genotype: A Randomized Controlled Trial J Nutr. 2022 07 06; 152(7):1655-1665. . View in PubMed
PNPLA3 Genotype, Arachidonic Acid Intake, and Unsaturated Fat Intake Influences Liver Fibrosis in Hispanic Youth with Obesity Nutrients. 2021 May 12; 13(5). . View in PubMed
CD52-targeted depletion by Alemtuzumab ameliorates allergic airway hyperreactivity and lung inflammation Mucosal Immunol. 2021 07; 14(4):899-911. . View in PubMed
Bile acids profile, histopathological indices and genetic variants for non-alcoholic fatty liver disease progression Metabolism. 2021 03; 116:154457. . View in PubMed
Noise Exposure and Distortion Product Otoacoustic Emission Suprathreshold Amplitudes: A Genome-Wide Association Study Audiol Neurootol. 2021; 26(6):445-453. . View in PubMed
Genetic evidence for independent causal relationships between metabolic biomarkers and risk of coronary artery diseases J Lipid Res. 2021; 62:100064. . View in PubMed
Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection J Lipid Res. 2021; 62:100061. . View in PubMed
Gene-Environment Interactions for Cardiovascular Disease Curr Atheroscler Rep. 2021 10 14; 23(12):75. . View in PubMed
APOE4 is associated with elevated blood lipids and lower levels of innate immune biomarkers in a tropical Amerindian subsistence population Elife. 2021 09 29; 10. . View in PubMed
Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality Eur Heart J. 2021 05 07; 42(18):1742-1756. . View in PubMed
Genome-wide analysis identifies novel susceptibility loci for myocardial infarction Eur Heart J. 2021 03 01; 42(9):919-933. . View in PubMed
The Genetics of Variation of the Wave 1 Amplitude of the Mouse Auditory Brainstem Response J Assoc Res Otolaryngol. 2020 08; 21(4):323-336. . View in PubMed
Toxicity of urban air pollution particulate matter in developing and adult mouse brain: Comparison of total and filter-eluted nanoparticles Environ Int. 2020 03; 136:105510. . View in PubMed
Dissecting the Genetic Architecture of Cystatin C in Diversity Outbred Mice G3 (Bethesda). 2020 07 07; 10(7):2529-2541. . View in PubMed
Adult mouse hippocampal transcriptome changes associated with long-term behavioral and metabolic effects of gestational air pollution toxicity Transl Psychiatry. 2020 07 07; 10(1):218. . View in PubMed
Association of Factor V Leiden With Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data Circulation. 2020 08 11; 142(6):546-555. . View in PubMed
Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma Nat Commun. 2020 04 15; 11(1):1776. . View in PubMed
A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity PLoS Genet. 2019 12; 15(12):e1008528. . View in PubMed
Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report Arterioscler Thromb Vasc Biol. 2019 06; 39(6):1045-1054. . View in PubMed
Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events Circ Genom Precis Med. 2019 04; 12(4):e002471. . View in PubMed
Subsequent Event Risk in Individuals With Established Coronary Heart Disease Circ Genom Precis Med. 2019 04; 12(4):e002470. . View in PubMed
Apolipoprotein E4 genotype in combination with poor metabolic profile is associated with reduced cognitive performance in healthy postmenopausal women: implications for late onset Alzheimer's disease Menopause. 2019 01; 26(1):7-15. . View in PubMed
Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease J Am Heart Assoc. 2019 05 21; 8(10):e011922. . View in PubMed
Exposure to Nanoscale Particulate Matter from Gestation to Adulthood Impairs Metabolic Homeostasis in Mice Sci Rep. 2019 02 12; 9(1):1816. . View in PubMed
Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes Nat Commun. 2019 02 12; 10(1):713. . View in PubMed
Effect of ApoE4 Genotype on the Association Between Metabolic Phenotype and Subclinical Atherosclerosis in Postmenopausal Women Am J Cardiol. 2019 10 01; 124(7):1031-1037. . View in PubMed
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk JCI Insight. 2018 03 22; 3(6). . View in PubMed
Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration Nat Genet. 2017 Sep; 49(9):1346-1353. . View in PubMed
Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions Circulation. 2017 Jun 13; 135(24):2336-2353. . View in PubMed
The Genetic Architecture of Coronary Artery Disease: Current Knowledge and Future Opportunities Curr Atheroscler Rep. 2017 Feb; 19(2):6. . View in PubMed
The in vivo T helper type 17 and regulatory T cell immune responses to Aggregatibacter actinomycetemcomitans Mol Oral Microbiol. 2017 12; 32(6):490-499. . View in PubMed
Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study Lancet Diabetes Endocrinol. 2017 07; 5(7):534-543. . View in PubMed
Apolipoprotein E4 is associated with improved cognitive function in Amazonian forager-horticulturalists with a high parasite burden FASEB J. 2017 04; 31(4):1508-1515. . View in PubMed
Proceedings of the 11th Congress of the International Society of Nutrigenetics and Nutrigenomics (ISNN 2017) J Nutrigenet Nutrigenomics. 2017; 10(5-6):155-162. . View in PubMed
Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity J Nutrigenet Nutrigenomics. 2017; 10(1-2):43-62. . View in PubMed
Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice J Assoc Res Otolaryngol. 2016 Oct; 17(5):417-31. . View in PubMed
Cognitive effects of estradiol after menopause: A randomized trial of the timing hypothesis Neurology. 2016 Aug 16; 87(7):699-708. . View in PubMed
Nutrigenomics, the Microbiome, and Gene-Environment Interactions: New Directions in Cardiovascular Disease Research, Prevention, and Treatment: A Scientific Statement From the American Heart Association Circ Cardiovasc Genet. 2016 Jun; 9(3):291-313. . View in PubMed
Expanding role of gut microbiota in lipid metabolism Curr Opin Lipidol. 2016 Apr; 27(2):141-7. . View in PubMed
Does near-roadway air pollution contribute to childhood obesity? Pediatr Obes. 2016 Feb; 11(1):1-3.. View in PubMed
Choline metabolites: gene by diet interactions Curr Opin Lipidol. 2016 Feb; 27(1):33-9. . View in PubMed
Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease Nat Commun. 2016 Jan 29; 7:10558. . View in PubMed
Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium Diabetes. 2016 07; 65(7):2072-80. . View in PubMed
Lower omental t-regulatory cell count is associated with higher fasting glucose and lower ß-cell function in adults with obesity Obesity (Silver Spring). 2016 06; 24(6):1274-82. . View in PubMed
The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits J Lipid Res. 2016 06; 57(6):925-42. . View in PubMed
Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalized Nutrition: Part 2 - Ethics, Challenges and Endeavors of Precision Nutrition J Nutrigenet Nutrigenomics. 2016; 9(1):28-46. . View in PubMed
An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease Genome Biol. 2016 08 11; 17(1):171. . View in PubMed
Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalised Nutrition: Part 1 - Fields of Precision Nutrition J Nutrigenet Nutrigenomics. 2016; 9(1):12-27. . View in PubMed
Ambient Air Pollution Is Associated With the Severity of Coronary Atherosclerosis and Incident Myocardial Infarction in Patients Undergoing Elective Cardiac Evaluation J Am Heart Assoc. 2016 07 28; 5(8). . View in PubMed
The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction G3 (Bethesda). 2016 10 13; 6(10):3219-3228. . View in PubMed
Contribution of Gut Bacteria to Lipid Levels: Another Metabolic Role for Microbes? Circ Res. 2015 Oct 09; 117(9):750-4.. View in PubMed
The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency-Specific Genetic Determinants G3 (Bethesda). 2015 Sep 04; 5(11):2329-39. . View in PubMed
Selected vitamin D metabolic gene variants and risk for autism spectrum disorder in the CHARGE Study Early Hum Dev. 2015 Aug; 91(8):483-9. . View in PubMed
The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice Stem Cell Reports. 2015 Jul 14; 5(1):125-38. . View in PubMed
Correction: Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss PLoS Genet. 2015 Jun; 11(6):e1005293. . View in PubMed
Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss PLoS Genet. 2015 Apr; 11(4):e1005094. . View in PubMed
Identification of a Novel Mucin Gene HCG22 Associated With Steroid-Induced Ocular Hypertension Invest Ophthalmol Vis Sci. 2015 Apr; 56(4):2737-48. . View in PubMed
Salsalate treatment improves glycemia without altering adipose tissue in nondiabetic obese hispanics Obesity (Silver Spring). 2015 Mar; 23(3):543-51. . View in PubMed
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction Nature. 2015 Feb 05; 518(7537):102-6. . View in PubMed
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation Nat Genet. 2015 11; 47(11):1282-1293. . View in PubMed
Genetic variation in MTNR1B is associated with gestational diabetes mellitus and contributes only to the absolute level of beta cell compensation in Mexican Americans Diabetologia. 2014 Jul; 57(7):1391-9. . View in PubMed
Comparative genome-wide association studies in mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and L-carnitine Arterioscler Thromb Vasc Biol. 2014 Jun; 34(6):1307-13. . View in PubMed
Macrophages and fibrosis in adipose tissue are linked to liver damage and metabolic risk in obese children Obesity (Silver Spring). 2014 Jun; 22(6):1512-9. . View in PubMed
Modifying influence of dietary sugar in the relationship between cortisol and visceral adipose tissue in minority youth Obesity (Silver Spring). 2014 Feb; 22(2):474-81. . View in PubMed
J Nutr. 2014 Feb; 144(2):123-31. . View in PubMed
Adipose tissue 11ßHSD1 gene expression, ßcell function and ectopic fat in obese African Americans versus Hispanics Obesity (Silver Spring). 2014 Jan; 22(1):14-8. . View in PubMed
Cognition, mood, and physiological concentrations of sex hormones in the early and late postmenopause Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20290-5. . View in PubMed
Genetic and clinical markers of elevated liver fat content in overweight and obese Hispanic children Obesity (Silver Spring). 2013 Dec; 21(12):E790-7. . View in PubMed
Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia Hum Mol Genet. 2013 Aug 15; 22(16):3381-93. . View in PubMed
Two chromosome 9p21 haplotype blocks distinguish between coronary artery disease and myocardial infarction risk Circ Cardiovasc Genet. 2013 Aug; 6(4):372-80. . View in PubMed
ALOX5 polymorphism associates with increased leukotriene production and reduced lung function and asthma control in children with poorly controlled asthma Clin Exp Allergy. 2013 May; 43(5):512-20. . View in PubMed
Aspirin hydrolysis in plasma is a variable function of butyrylcholinesterase and platelet-activating factor acetylhydrolase 1b2 (PAFAH1b2) J Biol Chem. 2013 Apr 26; 288(17):11940-8. . View in PubMed
Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis J Am Coll Cardiol. 2013 Mar 05; 61(9):957-70. . View in PubMed
Nutrigenetic response to omega-3 fatty acids in obese asthmatics (NOOA): rationale and methods Contemp Clin Trials. 2013 Mar; 34(2):326-35. . View in PubMed
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation Cell Metab. 2013 Jan 08; 17(1):49-60. . View in PubMed
Seventy-five genetic loci influencing the human red blood cell Nature. 2012 Dec 20; 492(7429):369-75. . View in PubMed
Clinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2803-12. . View in PubMed
Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits Mamm Genome. 2012 Oct; 23(9-10):680-92. . View in PubMed
Metabolic syndrome is linked to chromosome 7q21 and associated with genetic variants in CD36 and GNAT3 in Mexican Americans Obesity (Silver Spring). 2012 Oct; 20(10):2083-92. . View in PubMed
CXCL5 polymorphisms are associated with variable blood pressure in cardiovascular disease-free adults Hum Genomics. 2012 Aug 02; 6:9. . View in PubMed
Arachidonate 5-lipoxygenase gene variants affect response to fish oil supplementation by healthy African Americans J Nutr. 2012 Aug; 142(8):1417-28. . View in PubMed
Association of a genetic risk score with prevalent and incident myocardial infarction in subjects undergoing coronary angiography Circ Cardiovasc Genet. 2012 Aug 01; 5(4):441-9. . View in PubMed
Genetic-related and carbohydrate-related factors affecting liver fat accumulation Curr Opin Clin Nutr Metab Care. 2012 Jul; 15(4):392-6. . View in PubMed
Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study Am J Clin Nutr. 2012 Jul; 96(1):80-9. . View in PubMed
Association of PLA2G4A with myocardial infarction is modulated by dietary PUFAs Am J Clin Nutr. 2012 Apr; 95(4):959-65. . View in PubMed
Clinical and genetic association of serum ceruloplasmin with cardiovascular risk Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2):516-22. . View in PubMed
New gene functions in megakaryopoiesis and platelet formation Nature. 2011 Nov 30; 480(7376):201-8. . View in PubMed
Subcutaneous adipose tissue macrophage infiltration is associated with hepatic and visceral fat deposition, hyperinsulinemia, and stimulation of NF-? B stress pathway. Diabetes. 2011 Nov; 60(11):2802-9.. View in PubMed
Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome BMC Med Genet. 2011 Sep 29; 12:127. . View in PubMed
A novel g-1258G>A mutation in a conserved putative regulatory element of PAX9 is associated with autosomal dominant molar hypodontia. Clin Genet. 2011 Sep; 80(3):265-72. . View in PubMed
Prenatal vitamins, one-carbon metabolism gene variants, and risk for autism Epidemiology. 2011 Jul; 22(4):476-85. . View in PubMed
Genetic contribution of the leukotriene pathway to coronary artery disease Hum Genet. 2011 Jun; 129(6):617-27. . View in PubMed
ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation J Lipid Res. 2011 May; 52(5):991-1003. . View in PubMed
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease Nature. 2011 Apr 07; 472(7341):57-63. . View in PubMed
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease Nat Genet. 2011 Mar 06; 43(4):333-8. . View in PubMed
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project PLoS Genet. 2011 Feb 10; 7(2):e1001300. . View in PubMed
Genetic risk score and risk of myocardial infarction in Hispanics Circulation. 2011 Feb 01; 123(4):374-80. . View in PubMed
Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies Lancet. 2011 Jan 29; 377(9763):383-92. . View in PubMed
Inflammatory gene variants in the Tsimane, an indigenous Bolivian population with a high infectious load Biodemography Soc Biol. 2011; 57(1):33-52. . View in PubMed
Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption Am J Clin Nutr. 2010 Dec; 92(6):1522-7. . View in PubMed
Effects of PNPLA3 on liver fat and metabolic profile in Hispanic children and adolescents Diabetes. 2010 Dec; 59(12):3127-30. . View in PubMed
Lipoprotein(a) levels and long-term cardiovascular risk in the contemporary era of statin therapy J Lipid Res. 2010 Oct; 51(10):3055-61. . View in PubMed
Functional analysis of 5-lipoxygenase promoter repeat variants Hum Mol Genet. 2009 Dec 01; 18(23):4521-9. . View in PubMed
Additive effects of genetic variation in GCK and G6PC2 on insulin secretion and fasting glucose Diabetes. 2009 Dec; 58(12):2946-53. . View in PubMed
Evidence for sex-specific associations between variation in acid phosphatase locus 1 (ACP1) and insulin sensitivity in Mexican-Americans J Clin Endocrinol Metab. 2009 Oct; 94(10):4094-102. . View in PubMed
Genotyping the GGGCGG tandem repeat promoter polymorphism in the 5-lipoxygenase enzyme gene (ALOX5) by pyrosequencing assay Genet Test Mol Biomarkers. 2009 Jun; 13(3):361-5. . View in PubMed
Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans Obesity (Silver Spring). 2009 Apr; 17(4):729-36. . View in PubMed
A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus Hum Mol Genet. 2009 Feb 01; 18(3):569-79. . View in PubMed
Polyunsaturated fatty acids and cardiovascular disease: implications for nutrigenetics J Nutrigenet Nutrigenomics. 2009; 2(3):140-8. . View in PubMed
Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction Am J Clin Nutr. 2008 Oct; 88(4):934-40. . View in PubMed
Identification of ALOX5 as a gene regulating adiposity and pancreatic function Diabetologia. 2008 Jun; 51(6):978-88. . View in PubMed
Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease Hum Genet. 2008 May; 123(4):399-408. . View in PubMed
Allgrove syndrome in a Mexican American family is caused by an ancestral mutation derived from North Africa Clin Genet. 2008 Apr; 73(4):385-7. . View in PubMed
Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans Diabetes. 2008 Apr; 57(4):1048-56. . View in PubMed
Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk JAMA. 2008 Mar 19; 299(11):1265-76. . View in PubMed
Prevalence of common disease-associated variants in Asian Indians BMC Genet. 2008 Feb 04; 9:13. . View in PubMed
Non-conventional genetic risk factors for cardiovascular disease World Rev Nutr Diet. 2008; 98:62-76. . View in PubMed
FK506, a calcineurin inhibitor, prevents cadmium-induced testicular toxicity in mice Toxicol Sci. 2007 Dec; 100(2):474-85. . View in PubMed
The effect of montelukast and low-dose theophylline on cardiovascular disease risk factors in asthmatics Chest. 2007 Sep; 132(3):868-74. . View in PubMed
Genetics of gestational diabetes mellitus and type 2 diabetes Diabetes Care. 2007 Jul; 30 Suppl 2:S134-40. . View in PubMed
Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican Americans Diabetes. 2007 May; 56(5):1481-5. . View in PubMed
A new locus for autosomal dominant amelogenesis imperfecta on chromosome 8q243. Hum Genet. 2007 Jan; 120(5):653-62. . View in PubMed
Effect of obesity on clinical presentation and response to treatment in asthma J Asthma. 2006 Sep; 43(7):553-8. . View in PubMed
Nonconventional genetic risk factors for cardiovascular disease Curr Atheroscler Rep. 2006 May; 8(3):184-92. . View in PubMed
Using inbred mouse strains to identify genes for complex diseases Front Biosci. 2006 May 01; 11:1216-26. . View in PubMed
Influence of leukotriene pathway polymorphisms on response to montelukast in asthma Am J Respir Crit Care Med. 2006 Feb 15; 173(4):379-85. . View in PubMed
Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits Nat Genet. 2005 Nov; 37(11):1224-33. . View in PubMed
A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background Genomics. 2005 Sep; 86(3):259-70. . View in PubMed
The Collaborative Cross, a community resource for the genetic analysis of complex traits Nat Genet. 2004 Nov; 36(11):1133-7. . View in PubMed
Vascular cross-talk: a conversation Arterioscler Thromb Vasc Biol. 2004 Oct; 24(10):1748-9. . View in PubMed
Quantitative trait loci for apolipoprotein B, cholesterol, and triglycerides in familial combined hyperlipidemia pedigrees Arterioscler Thromb Vasc Biol. 2004 Oct; 24(10):1935-41. . View in PubMed
Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia Circ Res. 2004 Apr 16; 94(7):993-9. . View in PubMed
Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis N Engl J Med. 2004 Jan 01; 350(1):29-37. . View in PubMed
5-lipoxygenase and atherosclerosis Curr Opin Lipidol. 2003 Oct; 14(5):447-57. . View in PubMed
Using mice to dissect genetic factors in atherosclerosis Arterioscler Thromb Vasc Biol. 2003 Sep 01; 23(9):1501-9. . View in PubMed
Biochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia Circ Res. 2003 Jun 13; 92(11):1262-7. . View in PubMed
Combined analysis of genome scans of dutch and finnish families reveals a susceptibility locus for high-density lipoprotein cholesterol on chromosome 16q Am J Hum Genet. 2003 Apr; 72(4):903-17. . View in PubMed
Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice Circ Res. 2002 Jul 26; 91(2):120-6. . View in PubMed
Locus for elevated apolipoprotein B levels on chromosome 1p31 in families with familial combined hyperlipidemia Circ Res. 2002 May 03; 90(8):926-31. . View in PubMed
Understanding atherosclerosis through mouse genetics Curr Opin Lipidol. 2002 Apr; 13(2):181-9. . View in PubMed
Genome scan for blood pressure in Dutch dyslipidemic families reveals linkage to a locus on chromosome 4p Hypertension. 2001 Oct; 38(4):773-8. . View in PubMed
BiochemistryAn absorbing study of cholesterol. Science. 2000 Dec 01; 290(5497):1709-11. . View in PubMed
Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A Int J Obes Relat Metab Disord. 2000 Nov; 24(11):1381-91. . View in PubMed
Identification of TNFRSF1B as a novel modifier gene in familial combined hyperlipidemia Hum Mol Genet. 2000 Sep 01; 9(14):2067-74. . View in PubMed
A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2 J Lipid Res. 2000 Apr; 41(4):573-82. . View in PubMed
Contribution of the hepatic lipase gene to the atherogenic lipoprotein phenotype in familial combined hyperlipidemia J Lipid Res. 2000 Feb; 41(2):245-52. . View in PubMed
Linkage of a candidate gene locus to familial combined hyperlipidemia: lecithin:cholesterol acyltransferase on 16q Arterioscler Thromb Vasc Biol. 1999 Nov; 19(11):2730-6. . View in PubMed
A genome scan for familial combined hyperlipidemia reveals evidence of linkage with a locus on chromosome 11 Am J Hum Genet. 1999 Aug; 65(2):397-412. . View in PubMed
Novel genes for familial combined hyperlipidemia Curr Opin Lipidol. 1999 Apr; 10(2):113-22. . View in PubMed
Families with familial combined hyperlipidemia and families enriched for coronary artery disease share genetic determinants for the atherogenic lipoprotein phenotype Am J Hum Genet. 1998 Aug; 63(2):577-85. . View in PubMed
Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice J Clin Invest. 1994 Aug; 94(2):877-84. . View in PubMed