Faculty
Denis Evseenko
Contact
USC: USC Stevens Technology Advancement Grant, 2016
Wright Foundation: Wright Foundation Award, 2016
Arthritis National Research Foundation: James Klinenberg Award, 2015
Inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet bioRxiv. 2024 Apr 11. . View in PubMed
Influence of donor age and comorbidities on transduced human adipose-derived stem cell in vitro osteogenic potential Gene Ther. 2023 04; 30(3-4):369-376. . View in PubMed
Stability analysis of tranexamic acid in the presence of various antiseptic solutions J Orthop Res. 2023 03; 41(3):692-697. . View in PubMed
STAT3 promotes a youthful epigenetic state in articular chondrocytes Aging Cell. 2023 02; 22(2):e13773. . View in PubMed
Distinct human skeletal muscle-derived CD90 progenitor subsets for myo-fibro-adipogenic disease modeling and treatment in multiplexed conditions Front Cell Dev Biol. 2023; 11:1173794. . View in PubMed
Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis Sci Transl Med. 2023 03 22; 15(688):eabq2395. . View in PubMed
Author Correction: gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes Commun Biol. 2022 Feb 25; 5(1):200. . View in PubMed
gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes Commun Biol. 2022 01 17; 5(1):64. . View in PubMed
A new mouse model of post-traumatic joint injury allows to identify the contribution of Gli1+ mesenchymal progenitors in arthrofibrosis and acquired heterotopic endochondral ossification Front Cell Dev Biol. 2022; 10:954028. . View in PubMed
Cross-Communication Between Knee Osteoarthritis and Fibrosis: Molecular Pathways and Key Molecules Open Access J Sports Med. 2022; 13:1-15. . View in PubMed
Long-term repair of porcine articular cartilage using cryopreservable, clinically compatible human embryonic stem cell-derived chondrocytes NPJ Regen Med. 2021 Nov 23; 6(1):77. . View in PubMed
Zika virus NS3 protease induces bone morphogenetic protein-dependent brain calcification in human fetuses Nat Microbiol. 2021 04; 6(4):455-466. . View in PubMed
Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice Nat Commun. 2021 05 10; 12(1):2595. . View in PubMed
A Single-Cell Culture System for Dissecting Microenvironmental Signaling in Development and Disease of Cartilage Tissue Front Cell Dev Biol. 2021; 9:725854. . View in PubMed
A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells Cell Stem Cell. 2020 Jul 02; 27(1):181-185. . View in PubMed
Modulation of Hedgehog Signaling by Kappa Opioids to Attenuate Osteoarthritis Arthritis Rheumatol. 2020 08; 72(8):1278-1288. . View in PubMed
A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem CellsCell Stem Cell. 2020 07 02; 27(1):158-176. e10. . View in PubMed
Nomenclature Inconsistency and Selective Outcome Reporting Hinder Understanding of Stem Cell Therapy for the Knee J Bone Joint Surg Am. 2019 Jan 16; 101(2):186-195. . View in PubMed
Lentiviral Gene Therapy for Bone Repair Using Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Hum Gene Ther. 2019 07; 30(7):906-917. . View in PubMed
CaMKII inhibition in human primary and pluripotent stem cell-derived chondrocytes modulates effects of TGFß and BMP through SMAD signaling Osteoarthritis Cartilage. 2019 01; 27(1):158-171. . View in PubMed
In vitro behavior of tendon stem/progenitor cells on bioactive electrospun nanofiber membranes for tendon-bone tissue engineering applications Int J Nanomedicine. 2019; 14:5831-5848. . View in PubMed
Molecular characterization of physis tissue by RNA sequencing Gene. 2018 Aug 20; 668:87-96. . View in PubMed
Genetic ablation of adenosine receptor A3 results in articular cartilage degeneration J Mol Med (Berl). 2018 10; 96(10):1049-1060. . View in PubMed
Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair Ann Rheum Dis. 2018 05; 77(5):760-769. . View in PubMed
Correction to: Leukemia Inhibitory Factor Increases Survival of Pluripotent Stem Cell-Derived Cardiomyocytes J Cardiovasc Transl Res. 2018 02; 11(1):14. . View in PubMed
Leukemia Inhibitory Factor Increases Survival of Pluripotent Stem Cell-Derived Cardiomyocytes J Cardiovasc Transl Res. 2018 02; 11(1):1-13. . View in PubMed
ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs Nat Cell Biol. 2018 01; 20(1):46-57. . View in PubMed
A Small Molecule Mimetic of the Humanin Peptide as a Candidate for Modulating NMDA-Induced Neurotoxicity ACS Chem Neurosci. 2018 03 21; 9(3):462-468. . View in PubMed
Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes Nat Commun. 2018 09 07; 9(1):3634. . View in PubMed
Lactate dehydrogenase activity drives hair follicle stem cell activation Nat Cell Biol. 2017 Sep; 19(9):1017-1026. . View in PubMed
Perivascular Stem Cells Diminish Muscle Atrophy Following Massive Rotator Cuff Tears in a Small Animal Model J Bone Joint Surg Am. 2017 Feb 15; 99(4):331-341. . View in PubMed
The Wnt5a Receptor, Receptor Tyrosine Kinase-Like Orphan Receptor 2, Is a Predictive Cell Surface Marker of Human Mesenchymal Stem Cells with an Enhanced Capacity for Chondrogenic Differentiation Stem Cells. 2017 11; 35(11):2280-2291. . View in PubMed
Parylene scaffold for cartilage lesion Biomed Microdevices. 2017 06; 19(2):26. . View in PubMed
Kappa opioid receptor signaling protects cartilage tissue against posttraumatic degeneration JCI Insight. 2017 01 12; 2(1):e88553. . View in PubMed
Right-Left Differences in Knee Extension Stiffness for the Normal Rat Knee: In Vitro Measurements Using a New Testing Apparatus J Biomech Eng. 2016 Apr; 138(4):044501. . View in PubMed
Chondrocytes Cocultured with Stromal Vascular Fraction of Adipose Tissue Present More Intense Chondrogenic Characteristics Than with Adipose Stem Cells Tissue Eng Part A. 2016 Feb; 22(3-4):336-48. . View in PubMed
Hypoxic culture conditions induce increased metabolic rate and collagen gene expression in ACL-derived cells J Orthop Res. 2016 06; 34(6):985-94. . View in PubMed
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors Stem Cells. 2016 05; 34(5):1239-50. . View in PubMed
Adventitial Cells and Perictyes Support Chondrogenesis Through Different Mechanisms in 3-Dimensional Cultures With or Without Nanoscaffolds J Biomed Nanotechnol. 2015 Oct; 11(10):1799-807. . View in PubMed
Ensemble multivariate analysis to improve identification of articular cartilage disease in noisy Raman spectra J Biophotonics. 2015 Jul; 8(7):555-66. . View in PubMed
Covalently conjugated transforming growth factor-ß1 in modular chitosan hydrogels for the effective treatment of articular cartilage defects Biomater Sci. 2015 May; 3(5):742-52. . View in PubMed
Lysophosphatidic acid mediates fibrosis in injured joints by regulating collagen type I biosynthesis Osteoarthritis Cartilage. 2015 Feb; 23(2):308-18. . View in PubMed
Visible-light-initiated hydrogels preserving cartilage extracellular signaling for inducing chondrogenesis of mesenchymal stem cells Acta Biomater. 2015 Jan; 12:30-41. . View in PubMed
TGF-ß1 conjugated chitosan collagen hydrogels induce chondrogenic differentiation of human synovium-derived stem cells J Biol Eng. 2015; 9:1. . View in PubMed
Platelets contain tissue factor pathway inhibitor-2 derived from megakaryocytes and inhibits fibrinolysis J Biol Chem. 2014 Nov 07; 289(45):31647-61. . View in PubMed
Extracellular matrix domain formation as an indicator of chondrocyte dedifferentiation and hypertrophy Tissue Eng Part C Methods. 2014 Feb; 20(2):160-8. . View in PubMed
Rigid microenvironments promote cardiac differentiation of mouse and human embryonic stem cells Sci Technol Adv Mater. 2013 Aug 01; 14(2). . View in PubMed
Novel aspects of parenchymal-mesenchymal interactions: from cell types to molecules and beyond Cell Biochem Funct. 2013 Jun; 31(4):271-80. . View in PubMed
Perivascular support of human hematopoietic stem/progenitor cells Blood. 2013 Apr 11; 121(15):2891-901. . View in PubMed
Human developmental chondrogenesis as a basis for engineering chondrocytes from pluripotent stem cells Stem Cell Reports. 2013; 1(6):575-89. . View in PubMed
Lysophosphatidic acid mediates myeloid differentiation within the human bone marrow microenvironment PLoS One. 2013; 8(5):e63718. . View in PubMed
Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cells PLoS One. 2012; 7(10):e45603. . View in PubMed
Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation Placenta. 2011 Oct; 32(10):745-51. . View in PubMed
Dysregulated gene expression during hematopoietic differentiation from human embryonic stem cells Mol Ther. 2011 Apr; 19(4):768-81. . View in PubMed
Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cells Proc Natl Acad Sci U S A. 2010 Aug 03; 107(31):13742-7. . View in PubMed
Identification of the critical extracellular matrix proteins that promote human embryonic stem cell assembly Stem Cells Dev. 2009 Jul-Aug; 18(6):919-28. . View in PubMed
The ABC transporter BCRP/ABCG2 is a placental survival factor, and its expression is reduced in idiopathic human fetal growth restriction FASEB J. 2007 Nov; 21(13):3592-605. . View in PubMed
Expression, localisation and activity of ATP binding cassette (ABC) family of drug transporters in human amnion membranes Placenta. 2007 Aug-Sep; 28(8-9):868-77. . View in PubMed
Independent regulation of apical and basolateral drug transporter expression and function in placental trophoblasts by cytokines, steroids, and growth factors Drug Metab Dispos. 2007 Apr; 35(4):595-601. . View in PubMed
The xenobiotic transporter ABCG2 plays a novel role in differentiation of trophoblast-like BeWo cells Placenta. 2007 Apr; 28 Suppl A:S116-20. . View in PubMed
ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast Am J Physiol Regul Integr Comp Physiol. 2006 May; 290(5):R1357-65. . View in PubMed
Active transport across the human placenta: impact on drug efficacy and toxicity Expert Opin Drug Metab Toxicol. 2006 Feb; 2(1):51-69. . View in PubMed